Results 11 to 20 of about 215,114 (209)

HCV and Lymphoproliferation [PDF]

Clinical and Developmental Immunology, 2012
Hepatitis C virus (HCV) infection is a serious public health problem because of its worldwide diffusion and sequelae. It is not only a hepatotropic but also a lymphotropic agent and is responsible not only for liver injury—potentially evolving to cirrhosis and hepatocellular carcinoma—but also for a series of sometimes severely disabling extrahepatic ...
ZIGNEGO, ANNA LINDA, GIANNINI, CARLO, GRAGNANI, LAURA   +2 more
openaire   +6 more sources

Screening for HCV [PDF]

Canadian Medical Association Journal, 2014
We agree with Shah and colleagues[1][1] that the growing burden of chronic hepatitis C virus (HCV) infection poses a substantial public health concern. Managing HCV is difficult, because HCV is clinically silent for the majority of those infected.
William W L, Wong, Murray, Krahn
openaire   +5 more sources

High prevalence of anti-HCV antibodies in two metropolitan emergency departments in Germany : a prospective screening analysis of 28,809 patients [PDF]

, 2012
Background and Aims: The prevalence of hepatitis C virus (HCV) antibodies in Germany has been estimated to be in the range of 0.4–0.63%. Screening for HCV is recommended in patients with elevated ALT levels or significant risk factors for HCV ...
Hintereder, Gudrun, Gudrun Hintereder, Karin Hensel-Wiegel, Stefan Zeuzem, Lehmann, Ralf, Tauber, Rudolf, Vermehren, Johannes, Möckel, Martin, Annemarie Berger, Sarrazin, Christoph, Norbert Haas, Müller, Christian, Elanjimattom, Sandra, Christoph Sarrazin, Johannes Vermehren, Schlosser, Beate, Thomas Berg, Rudolf Tauber, Haas, Norbert, Martin Möckel, Walcher, Felix, Christian Müller, Domke, Diana, Diana Domke, Felix Walcher, Hensel-Wiegel, Karin, Berger, Annemarie, Berg, Thomas, Beate Schlosser, Zeuzem, Stefan, Sandra Elanjimattom, Ralf Lehmann, Berger Annemarie, Müller Christian, Lehmann Ralf, Zeuzem Stefan, Domke Diana, Walcher Felix, Möckel Martin, Hintereder Gudrun, Vermehren Johannes, Berg Thomas, Sarrazin Christoph, Tauber Rudolf, Schlosser Beate, Hensel-Wiegel Karin, Elanjimattom Sandra, Haas Norbert   +47 more
core   +2 more sources

HCV and the kidney [PDF]

Liver International, 2016
AbstractChronic hepatitis C (CHC) is significantly associated with a risk of renal deterioration over time. Renal impairment, especially stage 4–5 chronic kidney disease, increases the risk of: (i) the prevalence and incidence (in dialysis/transplantation) of hepatitis C virus (HCV) infection; (ii) liver deterioration during kidney transplantation and (
Marion, Corouge, Anaïs, Vallet-Pichard, Stanislas, Pol   +2 more
openaire   +2 more sources

Constrained pattern of viral evolution in acute and early HCV infection limits viral plasticity [PDF]

, 2011
Cellular immune responses during acute Hepatitis C virus (HCV) and HIV infection are a known correlate of infection outcome. Viral adaptation to these responses via mutation(s) within CD8+ T-cell epitopes allows these viruses to subvert host immune ...
Paul Klenerman, Malte Heeg, John, Mina, James, Ian, Ulsenheimer, Axel, Helmut M. Diepolder, Lucas, A.D., Silvana Gaudieri, Ian James, John, M., Andri Rauch, Klenerman, P., Simon Mallal, Heeg, Malte, Mallal, Simon, Lucas, Andrew, Nolan, D., Lucas, M., Heeg, M., Michaela Lucas, Diepolder, H.M., Mallal, S., Gaudieri, S., Nolan, David, David Nolan, Klenerman, Paul, Diepolder, Helmut M., Pfafferott, K., Rauch, A., Ulsenheimer, A., Pfafferott, Katja, Lucas, Michaela, Katja Pfafferott, Andrew Lucas, Rauch, Andri, Diepolder, Helmut M, Axel Ulsenheimer, Mina John, Helmut M Diepolder, James, I., Gaudieri, Silvana, Lucas Andrew, Mallal Simon, Diepolder Helmut M., Pfafferott Katja, Gaudieri Silvana, John Mina, Klenerman Paul, Ulsenheimer Axel, Lucas Michaela, Nolan David, Rauch Andri, James Ian, Heeg Malte   +53 more
core   +3 more sources

HCV core antigen and HCV-RNA in HIV/HCV co-infected patients with different HCV genotypes [PDF]

BMC Infectious Diseases, 2014
A good correlation between HCV core antigen (HCVAg) and different HCV-RNA assays has been described, but little data are available in HCV/HIV co-infection. We aimed to evaluate HCVAg in comparison with HCV-RNA and to determine their kinetics during antiviral treatment in selected HCV/HIV co-infected patients.355 samples from 286 HCV/HIV co-infected ...
Garbuglia, Anna Rosa, Monachetti, Alessia, Galli, Claudio, Sabatini, Rosella, Ferreri, Monica Lucia, Capobianchi, Maria Rosaria, Bagnarelli, Patrizia   +6 more
openaire   +2 more sources

Excluding hepatitis C virus (HCV) infection by serology in young infants of HCV infected mothers

, 2005
Aim: To identify the age at which HCV infection can be accurately excluded by serology in young children born to HCV-infected mothers and to determine an appropriate schedule of antibody testing, most informative to clinical practice.
FALDELLA, GIACOMO, England, K, . . . ], LANARI, MARCELLO, Pembrey, L, European Paediatric HCV Network [. . ., Tovo, PA, Newell, ML   +7 more
core   +2 more sources

Hepatocellular Carcinoma Post Direct Anti Hepatitis C Viral Agents; Clinical Features [PDF]

African Journal of Gastroenterology and Hepatology, 2022
Background:Direct Anti Hepatitis C Viral Agents (DAAs) were introduced for Hepatitis C Virus (HCV) infection management, which resulted in high sustained virological response (SVR) in many countries and a low failure rate.
Nabila Ahmed, Amira Elwan, Essam Abdelrahman, Ahmed Embaby, Ahmed Mohammed   +4 more
doaj   +1 more source

Dual function of the NK cell receptor 2B4 (CD244) in the regulation of HCV-specific CD8+ T cells [PDF]

, 2011
The outcome of viral infections is dependent on the function of CD8+ T cells which are tightly regulated by costimulatory molecules. The NK cell receptor 2B4 (CD244) is a transmembrane protein belonging to the Ig superfamily which can also be expressed ...
Lunemann, Sebastian, Bektas, Hueseyin, Heiner Wedemeyer, Wedemeyer Heiner, Suneetha, Pothakamuri Venkata, Grabowski, Jan, Michael Peter Manns, Markus Cornberg, Sarrazin, Christoph, Julia Dietz, Hueseyin Bektas, Christoph Sarrazin, Helfritz Fabian, Schlaphoff, Verena, Lunemann Sebastian, Fabian Helfritz, Suneetha Pothakamuri Venkata, Dietz, Julia, Jaroszewicz, Jerzy, Wedemeyer, Heiner, Bektas Hueseyin, Sebastian Lunemann, Pothakamuri Venkata Suneetha, Sarrazin Christoph, Manns Michael Peter, Jaroszewicz Jerzy, Jerzy Jaroszewicz, Helfritz, Fabian Arnold, Cornberg, Markus, Jan Grabowski, Schlaphoff Verena, Dietz Julia, Manns, Michael P., Verena Schlaphoff, Grabowski Jan, Cornberg Markus   +35 more
core   +2 more sources

ASSOCIATION BEETWEEN IL-28β POLYMORPHISMS AND EFFECTIVENESS OF CONCOMITANT THERAPY OF HIV INFECTION IN PATIENTS WITH HCV/HIV CO-INFECTION DURING THE ANTIVIRAL THERAPY

Инфекция и иммунитет, 2014
. The aim of the study was  to evaluate the associations between the polymorphism rs8099917 IL-28β and changing of HIV viral load and the effectiveness of high active antiretroviral therapy during the treatment of chronic hepatitis C in HIV-infected ...
E. S. Kovaleva
doaj   +1 more source