Results 11 to 20 of about 20,565,397 (156)

Hepatitis B and C virus infections and associated factors among HIV-positive and HIV-negative tuberculosis patients in public health facilities, Northeast Ethiopia: A comparative cross-sectional study

open access: yesSAGE Open Medicine, 2023
Objective: Viral hepatitis, particularly hepatitis B virus and hepatitis C virus, is the leading cause of global liver-related morbidity and mortality.
Alemu Gedefie   +5 more
doaj   +1 more source

Hepatitis C virus evasion mechanisms from neutralizing antibodies [PDF]

open access: yes, 2011
Hepatitis C virus (HCV) represents a major public health problem, affecting 3% of the world’s population. The majority of infected individuals develop chronic hepatitis, which can progress to cirrhosis and hepatocellular carcinoma.
Angus, Allan G.N.   +5 more
core   +1 more source

Early predictive efficacy of core antigen on antiviral outcomes in genotype 1 hepatitis C virus infected patients

open access: yesBrazilian Journal of Infectious Diseases, 2015
Response-guided therapy is of limited use in developing countries because hepatitis C virus RNA detection by sensitive molecular methods is time- and labor-consuming and expensive.
Bo Feng   +8 more
doaj   +1 more source

Evidence of viral adaptation to HLA class I-restricted immune pressure in chronic hepatitis C virus infection [PDF]

open access: yes, 2006
Cellular immune responses are an important correlate of hepatitis C virus (HCV) infection outcome. These responses are governed by the host's human leukocyte antigen (HLA) type, and HLA-restricted viral escape mutants are a critical aspect of this host ...
Cheng, Wendy   +57 more
core   +1 more source

Hepatitis C Virus Exploits Death Receptor 6-mediated Signaling Pathway to Facilitate Viral Propagation

open access: yesScientific Reports, 2017
The life cycle of hepatitis C virus (HCV) is highly dependent on host proteins for virus propagation. By transcriptome sequencing analysis, we identified host genes that were highly differentially expressed in HCV-infected cells.
Trang T. D. Luong   +4 more
doaj   +1 more source

A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C [PDF]

open access: yes, 2012
Background: To perform a comprehensive study on the relationship between vitamin D metabolism and the response to interferon-α-based therapy of chronic hepatitis C.
Jörg Bojunga   +111 more
core   +2 more sources

Hepatitis C virus infection [PDF]

open access: yesCanadian Medical Association Journal, 2015
Hepatitis C virus (HCV) results in more lost years of life and more illness than any infectious disease in Ontario.[1][1] Screening individuals born between 1945 and 1965 using an anti-HCV antibody test is currently recommended in the United States.[2][2] A similar approach appears to be cost-
Michael, Fralick, Jordan J, Feld
openaire   +2 more sources

Performance study of the automated immunoassay test anti-hepatitis C virus VIDAS® for the qualitative detection of antibodies anti-hepatitis C virus

open access: yesMicrobiologia Medica, 2016
Background and aims: Hepatitis C virus (HCV) represents a major worldwide public health problem requiring global action for the diagnosis, treatment and prevention of this infection.
Sara Salvetti   +2 more
doaj   +1 more source

Opportunities and Challenges: Hepatitis C Testing and Treatment Access Experiences Among People in Methadone and Buprenorphine Treatment During COVID-19, Arizona, 2021

open access: yesAJPM Focus, 2023
Introduction: The purpose of this study was to characterize hepatitis C virus screening and treatment access experiences among people in treatment for opioid use disorder in Arizona during COVID-19.
Beth E. Meyerson, PhD   +13 more
doaj   +1 more source

Hepatitis C virus and hepatocarcinogenesis

open access: yesClinical and Molecular Hepatology, 2012
Hepatitis C virus (HCV) is an RNA virus that is unable to integrate into the host genome. However, its proteins interact with various host proteins and induce host responses. The oncogenic process of HCV infection is slow and insidious and probably requires multiple steps of genetic and epigenetic alterations, the activation of cellular oncogenes, the ...
Jeong, Soung Won   +2 more
openaire   +5 more sources

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