Results 11 to 20 of about 20,565,397 (156)
Objective: Viral hepatitis, particularly hepatitis B virus and hepatitis C virus, is the leading cause of global liver-related morbidity and mortality.
Alemu Gedefie +5 more
doaj +1 more source
Hepatitis C virus evasion mechanisms from neutralizing antibodies [PDF]
Hepatitis C virus (HCV) represents a major public health problem, affecting 3% of the world’s population. The majority of infected individuals develop chronic hepatitis, which can progress to cirrhosis and hepatocellular carcinoma.
Angus, Allan G.N. +5 more
core +1 more source
Response-guided therapy is of limited use in developing countries because hepatitis C virus RNA detection by sensitive molecular methods is time- and labor-consuming and expensive.
Bo Feng +8 more
doaj +1 more source
Evidence of viral adaptation to HLA class I-restricted immune pressure in chronic hepatitis C virus infection [PDF]
Cellular immune responses are an important correlate of hepatitis C virus (HCV) infection outcome. These responses are governed by the host's human leukocyte antigen (HLA) type, and HLA-restricted viral escape mutants are a critical aspect of this host ...
Cheng, Wendy +57 more
core +1 more source
The life cycle of hepatitis C virus (HCV) is highly dependent on host proteins for virus propagation. By transcriptome sequencing analysis, we identified host genes that were highly differentially expressed in HCV-infected cells.
Trang T. D. Luong +4 more
doaj +1 more source
A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C [PDF]
Background: To perform a comprehensive study on the relationship between vitamin D metabolism and the response to interferon-α-based therapy of chronic hepatitis C.
Jörg Bojunga +111 more
core +2 more sources
Hepatitis C virus infection [PDF]
Hepatitis C virus (HCV) results in more lost years of life and more illness than any infectious disease in Ontario.[1][1] Screening individuals born between 1945 and 1965 using an anti-HCV antibody test is currently recommended in the United States.[2][2] A similar approach appears to be cost-
Michael, Fralick, Jordan J, Feld
openaire +2 more sources
Background and aims: Hepatitis C virus (HCV) represents a major worldwide public health problem requiring global action for the diagnosis, treatment and prevention of this infection.
Sara Salvetti +2 more
doaj +1 more source
Introduction: The purpose of this study was to characterize hepatitis C virus screening and treatment access experiences among people in treatment for opioid use disorder in Arizona during COVID-19.
Beth E. Meyerson, PhD +13 more
doaj +1 more source
Hepatitis C virus and hepatocarcinogenesis
Hepatitis C virus (HCV) is an RNA virus that is unable to integrate into the host genome. However, its proteins interact with various host proteins and induce host responses. The oncogenic process of HCV infection is slow and insidious and probably requires multiple steps of genetic and epigenetic alterations, the activation of cellular oncogenes, the ...
Jeong, Soung Won +2 more
openaire +5 more sources

