Results 21 to 30 of about 20,565,397 (156)

Hepatitis C virus p7 protein is crucial for assembly and release of infectious virions [PDF]

open access: yes, 2007
Hepatitis C virus (HCV) infection is associated with chronic liver disease and currently affects about 3% of the world population. Although much has been learned about the function of individual viral proteins, the role of the HCV p7 protein in virus ...
Ralf Bartenschlager   +17 more
core   +1 more source

Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation [PDF]

open access: yes, 2010
End-stage liver disease caused by chronic hepatitis C virus (HCV) infection is a leading cause for liver transplantation (LT). Due to viral evasion from host immune responses and the absence of preventive antiviral strategies, reinfection of the graft is
Pessaux, Patrick   +38 more
core   +1 more source

Anti-hepatitis C virus treatment may prevent the progression of liver fibrosis in non-responder human immunodeficiency virus/hepatitis C virus coinfected patients

open access: yesBrazilian Journal of Infectious Diseases, 2014
Aim: To evaluate changes in liver histology in patients with human immunodeficiency virus/hepatitis C virus coinfection non-responders to a suboptimal Interferon + Ribavirine regimen. Materials and methods: We investigated 49 patients with two sequential
Caterina Sagnelli   +8 more
doaj   +1 more source

Geographical and chronological origin and evolution of Hepatitis C Virus. [PDF]

open access: yes, 2011
Hepatitis C Virus (HCV) infection is a major health problem that leads to cirrhosis and hepatocellular carcinoma. World over, more than 270-300 million people are estimated to be infected with the virus.
Sugunan V.S.   +2 more
core   +1 more source

Delayed Viral Clearance after 6-Week Treatment with Peginterferon Plus Ribavirin in a Patient with Chronic Hepatitis C Virus Genotype 1b

open access: yesCase Reports in Gastroenterology, 2016
Following interferon-based therapy for chronic hepatitis C, the negativity of hepatitis C virus RNA is essential to achieve viral clearance at the end of treatment.
Akira Sato   +5 more
doaj   +1 more source

Hepatitis C virus and autoimmunity [PDF]

open access: yesAutoimmunity Highlights, 2010
Hepatitis C virus infection is associated with several extrahepatic manifestations. About 60% of patients infected with HCV develop at least one extrahepatic manifestation. The majority of these diseases seem to be triggered through autoimmune mechanisms, such as autoantibody production, autoreactive T cells and complex autoimmune mechanisms leading to
Böckle, Barbara C., Sepp, Norbert T.
openaire   +2 more sources

Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors [PDF]

open access: yes, 2010
Hepatitis C virus (HCV) naturally infects only humans and chimpanzees. The determinants responsible for this narrow species tropism are not well defined.
Christiane Brohm   +25 more
core   +2 more sources

Hepatitis C action plan for Scotland : phase II (May 2008 - March 2011) [PDF]

open access: yes, 2008
In 2004, the Scottish Government recognised that 'Hepatitis C is one of the most serious and significant public health risks of our generation' [1]. By December 2006, Health Protection Scotland (HPS) estimated that 50,000 people in Scotland had been ...
Brown, G.   +8 more
core   +2 more sources

Factors associated with testing for hepatitis C in an internet-recruited sample of men who have sex with men.

open access: yes, 2001
BACKGROUND: Nearly 4 million individuals in the United States (1.8%) have been infected with hepatitis C virus, yet few are aware of their infection. GOAL: To identify correlates associated with hepatitis C virus testing among a sample of men who have ...
Diclemente, RJ   +7 more
core   +1 more source

Immune restoration in human immunodeficiency virus and hepatitis C virus coinfected patients after highly active antiretroviral therapy

open access: yesBrazilian Journal of Infectious Diseases, 2013
Objective: To evaluate the influence of hepatitis C virus on immunological and virological responses after highly active antiretroviral therapy initiation in human immunodeficiency virus/hepatitis C virus coinfected patients compared to monoinfected ...
Vicente Sperb Antonello   +4 more
doaj   +3 more sources

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