Results 201 to 210 of about 1,924,182 (309)

The TLR7 agonist vesatolimod does not measurably induce SIV expression in macaques receiving combination antiretroviral therapy initiated during chronic infection. [PDF]

Antimicrob Agents Chemother
Swanstrom AE, Oswald K, Fast R, Shoemaker R, Thomas JA, Pyle C, Hull M, Bosche WJ, Li Y, Breed MW, Kramer JA, Donohue D, Trubey CM, Deleage C, Geleziunas R, Lifson JD, Del Prete GQ.   +16 more
europepmc   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

Gfi1 controls the formation of effector-like CD8⁺ T cells during chronic infection and cancer. [PDF]

Nat Commun
Ojo OA, Shen H, Ingram JT, Bonner JA, Welner RS, Lacaud G, Zajac AJ, Shi LZ.   +7 more
europepmc   +1 more source

Reconfigurable Magnetic Soft Microrobot for Acoustically Triggered Targeted Bacterial Sterilization

Advanced Functional Materials, EarlyView.
Reconfigurable magnetic soft microrobots integrate in situ‐grown piezoelectric zinc oxide nanorods that produce reactive oxygen species upon acoustic excitation. Combining magnetically guided transport with thermally induced planar reconfiguration, the microrobots achieve targeted delivery and enhanced bacterial sterilization through efficient on ...
Quan Gao, Fan Li, Jiajie Gao, Elric Zhang, Yingdong Su, Ni Qin, Hao Ye, Josep Puigmartí, Giuseppe Cantarella, Simone Schuerle, Jiang Wu, Bradley J. Nelson, Salvador Pané   +12 more
wiley   +1 more source

Inhibition of GPX4 by <i>Toxoplasma gondii</i> Promotes Ferroptosis and Enhances Its Proliferation in Acute and Chronic Infection. [PDF]

Cells
Gu Y, Niu Z, Lu HH, Li SA, Zhou DH.
europepmc   +1 more source

Chronic Infective Metritis.* [PDF]

BJOG: An International Journal of Obstetrics & Gynaecology, 1906
openaire   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Helicobacter pylori luxS mutants cause hyperinflammatory responses during chronic infection. [PDF]

Microbiol Spectr
Yang C, Rodriguez Y Baena A, Manso BA, Hu S, Lopez-Magaña R, Ohanyan M, Ottemann KM.   +6 more
europepmc   +1 more source

RNA‐Micelles as Self‐Assembling Structures for Efficient Co‐Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung Metastasis

Advanced Functional Materials, EarlyView.
Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin, Piotr Rychahou, Daniel W. Binzel, B. Mark Evers, Peixuan Guo   +4 more
wiley   +1 more source

<i>Toxoplasma gondii</i> PROP1 is critical for autophagy and parasite viability during chronic infection. [PDF]

mSphere
Thaprawat P, Wang F, Chalasani S, Schultz TL, Di Cristina M, Carruthers VB.   +5 more
europepmc   +1 more source