A common HLA-DPA1 variant is associated with hepatitis B virus infection but fails to distinguish active from inactive Caucasian carriers [PDF]
, 2012 Background and Aims: Chronic infection with the hepatitis B virus (HBV) is a major health issue worldwide. Recently, single nucleotide polymorphisms (SNPs) within the human leukocyte antigen (HLA)-DP locus were identified to be associated with HBV ...
Vermehren, Johannes +7 more
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Describing Chronic Malaria Infections [PDF]
The American Journal of Tropical Medicine and Hygiene, 2019 Taylor-Robinson, AW orcid:0000-0001-7342-8348 ; I read with interest the recent thought-provoking article by Dennis Shanks [1]. This discusses the state of anti-disease resistance that may be eventually achieved by a person if s/he is repeatedly exposed to infection with Plasmodium falciparum, assuming that no infectious episode has a fatal outcome ...
openaire +6 more sources
Molecules, 2022 The heterocyclic indole structure has been shown to be one of the most promising scaffolds, offering various medicinal advantages from its wide range of biological activity. Nonetheless, the significance of 3-oxindole has been less known.
Dong-Eun Kim +7 more
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Urinary porphyrin excretion in hepatitis C infection [PDF]
, 1999 A high prevalence of hepatitis C virus infection in porphyria cutanea tarda in some populations suggests a close link between viral hepatitis and alteration of porphyrin metabolism.
Jacob, Karl +2 more
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Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection. [PDF]
, 2020 Mucosa-associated invariant T (MAIT) cell loss in chronic HIV-1 infection is a significant insult to antimicrobial immune defenses. Here we investigate the response of MAIT cells during acute HIV-1 infection utilizing the RV217 cohort with paired ...
Ananworanich, Jintanat +23 more
core
A laminar flow model of aerosol survival of epidemic and non-epidemic strains of Pseudomonas aeruginosa isolated from people with cystic fibrosis [PDF]
, 2008 Cystic fibrosis (CF) is an inherited multi-system disorder characterised by chronic airway infection with pathogens such as Pseudomonas aeruginosa. Acquisition of P. aeruginosa by patients with CF is usually from the environment, but recent studies have
Beggs, Clive B. +4 more
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Prostaglandin E2 promotes features of replicative senescence in chronically activated human CD8+ T cells. [PDF]
, 2014 Prostaglandin E2 (PGE2), a pleiotropic immunomodulatory molecule, and its free radical catalyzed isoform, iso-PGE2, are frequently elevated in the context of cancer and chronic infection.
Chou, Jennifer P +4 more
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Decrease in health-related quality of life associated with awareness of hepatitis C virus infection among people who inject drugs in Scotland [PDF]
, 2013 Chronic hepatitis C virus (HCV) infection can significantly reduce health-related quality of life (QoL), but it is not clear if reduction is associated with the infection or with being aware of one's infection status.
Allen, Elizabeth +6 more
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Obstetrics and Gynecology International, 2013 Cervical cancer is the second most common cause of death from cancer in women worldwide, and the development of new diagnostic, prognostic, and treatment strategies merits special attention.
Oscar Peralta-Zaragoza +5 more
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Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model [PDF]
, 2016 Chronic obesity and Chagas disease (caused by the protozoan Trypanosoma cruzi) represent serious public health concerns. The interrelation between parasite infection, adipose tissue, immune system and metabolism in an obesogenic context, has not been ...
Andrada, Marta Cecilia +8 more
core +4 more sources