Results 191 to 200 of about 2,740,979 (275)

Trajectory of macrotroponin in a community cohort

Internal Medicine Journal, EarlyView.
Abstract Background Cardiac troponin I (cTnI) is a biomarker for myocardial injury. However, macrotroponin, a complex of cTnI and endogenous cardiac troponin autoantibodies, may artefactually elevate cTnI levels with potential to mislead clinicians, leading to inappropriate investigation and management.
Duncan J. Campbell, Fei Fei Gong, Michele McGrady, David L. Prior, Christopher M. Reid, Christina M. Trambas   +5 more
wiley   +1 more source

B-Cell Immune Responses in Myocarditis: Mechanisms, B-Cell Receptor Repertoire, and Clinical Translation. [PDF]

Cells
Lin X, Yao X, Li J.
europepmc   +1 more source

Frequent Premature Ventricular Complexes and Catheter Ablation for Atrial Fibrillation

Journal of Cardiovascular Electrophysiology, EarlyView.
Among 421 patients undergoing ablation of atrial fibrillation, frequent premature ventricular complexes (PVCs) > 1% were present in a significant proportion of patients at baseline. The PVC burden did not increase significantly in the post‐AF ablation period and was not associated with a higher rate of recurrent AF.
Abdulmohsen Alshakhs, Jason G. Andrade, Nathaniel M. Hawkins, Zachary W. Laksman, Richard G. Bennett, John A. Yeung‐Lai‐Wah, Santabhanu Chakrabarti, Matthew T. Bennett, Andrew D. Krahn, Marc W. Deyell   +9 more
wiley   +1 more source

Heart Failure with Recovered Ejection Fraction: EGPA-Associated Cardiomyopathy Treated with Benralizumab. [PDF]

J Clin Med
Bangari LR, Khand Y, Yadav V, Desai A, Muniz A, Ruiz J, Nativi-Nicolau J, Leoni J, Patel P, Goswami R.   +9 more
europepmc   +1 more source

LGR6 couples maresin 1 signaling to glycolytic flux and protein lactylation for the rescue of diabetic cardiomyopathy

Journal of Diabetes Investigation, EarlyView.
MaR1 activates LGR6‐AMPK signaling to restore metabolic flexibility in diabetic hearts. Glycolytic recovery replenishes intracellular lactate to rescue protective protein lysine lactylation, which reactivates PINK1/Parkin‐mediated mitophagy to eliminate damaged mitochondria.
Bin Feng, Chao Chen, Lin Chen, Yuqiong Chen, Wenjun Mao, Peiran Yu, Hao Yu, Bimin Shi, Nannan Zhang   +8 more
wiley   +1 more source

Inflammation and metabolic dysregulation in diabetic cardiomyopathy

Diabetic cardiomyopathy is characterized by structural and functional alterations in the heart muscle of people with diabetes that finally lead to heart failure.
Vázquez Carrera, Manuel, Palomer Tarridas, Francesc Xavier, Barroso Fernández, Emma   +2 more
core  

Expression of inflammatory mediators and differential progression of acute myocarditis and chronic experimental chagasic cardiomyopathy in Syrian hamsters infected with Trypanosoma cruzi [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 2006
openaire   +3 more sources

USP25 promotes ferroptosis in diabetic retinopathy by deubiquitinating p53 and suppressing the GPX4/SLC7A11 axis

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Objective To explore the expression of the deubiquitinase (DUB) USP25 in diabetic retinopathy (DR) and its mechanistic role in regulating ferroptosis. Methods Bioinformatics was used to screen for DR‐related DUB candidate genes. USP25 expression was validated in a streptozotocin‐induced diabetic mouse model and high glucose (HG)‐treated ARPE ...
Yanjun Gao, Wenjing Zhao, Qiannan Chai, Cunxi Ye   +3 more
wiley   +1 more source

Trypanosoma cruzi Cardiomyopathy Diagnosed via Explant Tissue 28S Ribosomal Gene Sequencing Following Orthotopic Heart Transplantation. [PDF]

Cureus
Fernandez AC, Berry GJ, Ahanonu R, Ferguson Toll J.   +3 more
europepmc   +1 more source

Cell Therapy for Periodontal, Soft‐Tissue, and Craniofacial Regeneration

Journal of Periodontal Research, EarlyView.
The clinical translation of mesenchymal stem/stromal cells (MSCs) represents a major advancement in dentistry, especially for periodontal, soft‐tissue, and craniofacial regeneration. However, several challenges remain to be addressed, including the absence of standardised protocols, limited scalability, regulatory hurdles, a lack of well‐controlled ...
Kamal Mustafa, Shuntaro Yamada, Nerea Sanchez, Magdalena Mayol, Cecilie Gjerde, Mariano Sanz   +5 more
wiley   +1 more source