Results 201 to 210 of about 2,740,979 (275)

Daridorexant‐ Case Report of Possible Side‐Effect in Rare Mitochondrial Disorder

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT This case report describes a 40‐year‐old woman with maternally inherited diabetes and deafness (MIDD), a rare mitochondrial disorder, who received treatment with daridorexant due to severe chronic insomnia. She developed progression of her MIDD symptoms during treatment.
Sven Svedmyr, Joel Bergqvist
wiley   +1 more source

Cardiovascular Outcomes of GLP‐1–Based Medicines Among People With Overweight and Obesity: An Umbrella Review of Meta‐Analyses of Randomized Controlled Trials

open access: yesObesity Reviews, EarlyView.
ABSTRACT Introduction Cardiovascular (CV) outcomes of Glucagon‐like peptide‐1 (GLP‐1)–based medicines among people with overweight and obese (OW/OB) population have been investigated by meta‐analyses of randomized controlled trials (RCTs), but an overall summary is lacking.
Muhammed Rashid   +6 more
wiley   +1 more source

Targeting Overweight and Obesity Phenotypes for Secondary Prevention of Cardiovascular Disease: A Call to Action for the Middle East and Beyond

open access: yesObesity Reviews, EarlyView.
ABSTRACT Although there are conflicting clinical data on the efficacy of weight reduction in reducing secondary events in patients with comorbid overweight and obesity (OAO) and cardiovascular disease (CVD), there is excellent epidemiological and biological evidence of a cause–effect relationship between OAO, CVD, and other systemic complications ...
Wael Almahmeed   +19 more
wiley   +1 more source

Red‐Complex Bacterial DNA in Carotid Atheroma of Dentate and Long‐Term Edentulous Patients and Its Association With Mitochondrial DNA Copy Number

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective This study aimed to evaluate (i) the presence of red complex bacteria in carotid atheroma plaques of dentate and edentulous patients and (ii) the possible relationship between mitochondrial DNA copy number (mtDNA‐cn), an indicator of mitochondrial function, and periodontal disease.
Ayşe Toraman   +4 more
wiley   +1 more source

Expert Recommendations for Use of Combined Oral Contraceptives in Preadolescent and Young Adolescent Patients With Acne Vulgaris

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Acne vulgaris commonly presents in early adolescence with the onset of adrenarche. Treatments for acne in this age group typically mirror those in older adolescents. However, while combined oral contraceptives are an effective hormonal treatment for acne vulgaris in young women, the safety of using a systemic hormonal therapy in younger ...
Andrea L. Zaenglein   +18 more
wiley   +1 more source

Fatigue Interventions in Patients With Chronic Obstructive Pulmonary Disease and Heart Diseases: A Systematic Review and Meta‐Analysis

open access: yesPublic Health Nursing, EarlyView.
ABSTRACT Background Fatigue is a significant yet under‐addressed symptom in chronic obstructive pulmonary disease (COPD) and heart diseases, impairing quality of life. This systematic review aims to investigate the effectiveness of rehabilitation interventions, including exercise and psychosocial support, in managing fatigue in COPD, ischemic heart ...
Fie Grünfeld Holmgaard   +3 more
wiley   +1 more source

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