Myocarditis is a common inflammatory cardiomyopathy, associated with cardiomyocyte apoptosis, which can lead to chronic left ventricular dysfunction. Under conventional heart failure therapy, inflammatory cardiomyopathy typically has a progressive course,
Kapka Miteva +3 more
doaj +2 more sources
Colchicine in patients with chronic inflammatory cardiomyopathy: rationale and design of the CMP-MYTHiC. [PDF]
Abstract Introduction Acute myocarditis can lead to chronic inflammatory cardiomyopathy (Infl-CMP), a condition characterized by increased risk of ventricular arrhythmias (VA), left ventricular (LV) systolic dysfunction (LVSD), and heart failure (HF).
Ammirati E +32 more
europepmc +7 more sources
Cardiovascular magnetic resonance (CMR) and positron emission tomography (PET) imaging in the diagnosis and follow-up of patients with acute myocarditis and chronic inflammatory cardiomyopathy : A review paper with practical recommendations on behalf of the European Society of Cardiovascular Radiology (ESCR). [PDF]
AbstractAdvanced cardiac imaging techniques such as cardiovascular magnetic resonance (CMR) and positron emission tomography (PET) are widely used in clinical practice in patients with acute myocarditis and chronic inflammatory cardiomyopathies (I-CMP).
Caobelli F +7 more
europepmc +5 more sources
The efficacy and safety of hydroxychloroquine in patients with chronic inflammatory cardiomyopathy: a multicenter randomized study (HYPIC trial). [PDF]
Chronic inflammatory cardiomyopathy (infl-CMP) is a long-term sequela caused by the chronicity of acute myocarditis, especially fulminant myocarditis (FM). Hydroxychloroquine (HCQ) may benefit these patients by inhibiting the excessive inflammatory response.In this multicenter, randomized trial, we evaluated the efficacy and safety of HCQ in patients ...
He W +9 more
europepmc +4 more sources
115 Prognostic significance of iron deficiency status in chronic inflammatory cardiomyopathy [PDF]
Abstract Aims Iron deficiency (ID) and associated anaemia (IDA) represent major comorbidities in chronic diseases. However, their prevalence and prognostic significance have never been investigated in chronic inflammatory cardiomyopathy (CIC).
Giovanni Peretto +2 more
openaire +1 more source
Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy [PDF]
Myocarditis can develop into inflammatory cardiomyopathy through chronic stimulation of myosin heavy chain 6-specific T helper (T-H)1 and T(H)17 cells. However, mechanisms governing the cardiotoxicity programming of heart-specific T cells have remained ...
Markus Arnoldini +86 more
core +3 more sources
Although the frequency of myocarditis in the general population is very difficult to accurately determine due to the large number of asymptomatic cases, the incidence of this disease is increasing significantly due to better defined criteria for ...
Ratko Lasica +8 more
doaj +1 more source
Immunohistological evidence for a chronic intramyocardial inflammatory process in dilated cardiomyopathy. [PDF]
OBJECTIVE: To determine whether immunohistochemical analysis of cardiac biopsies from patients presenting clinically as dilated cardiomyopathy (DCM) show a chronic inflammatory process. DESIGN: Comparative case control study. SETTING: Tertiary referral centre.
U, Kühl +3 more
openaire +2 more sources
Macrophage DCLK1 promotes obesity-induced cardiomyopathy via activating RIP2/TAK1 signaling pathway
Obesity increases the risk for cardiovascular diseases and induces cardiomyopathy. Chronic inflammation plays a significant role in obesity-induced cardiomyopathy and may provide new therapeutic targets for this disease. Doublecortin-like kinase 1 (DCLK1)
Bin Yang +8 more
doaj +1 more source
Summary: Takotsubo cardiomyopathy is an acute stress-induced heart failure syndrome for which the exact pathogenic mechanisms are unclear, and consequently, no specific treatment exists.
Heather M. Wilson, BSc, PhD +8 more
doaj +1 more source

