Mixed lineage kinase 3 mediates SARS‐CoV‐2‐induced kidney injury via the Hsp70‐IL‐17A axis
Kidney samples from patients infected with severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) showed upregulated expression and activity of Mixed Lineage Kinase (MLK3). Based on the mechanistic studies, we identified MLK3 as a critical player in promoting SARS‐CoV‐2‐induced kidney injury.
Sandeep Kumar +18 more
wiley +1 more source
Molecular theranostics: principles, challenges and controversies
Molecular theranostics offers a powerful tool to drive precision medicine in nuclear oncology. While theranostics is not a new principle in nuclear medicine, recent advances in instrumentation and radiopharmacy have driven a reinvigoration and a broader suite of applications.
Geoffrey Currie
wiley +1 more source
Therapeutic Impact on Quality of Life in Adult Patients With Chronic Intestinal Pseudo-obstruction: A Multicenter, Cohort Study. [PDF]
Takahashi K +16 more
europepmc +1 more source
Chronic Intestinal Pseudo-Obstruction Due to Incidentally Found Thymoma. [PDF]
Castaneda D +5 more
europepmc +1 more source
Abstract The Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) recognized the need to define research priorities and identify knowledge gaps to guide future investigations in pediatric digestive health. Following international examples, SIGENP aimed to provide a structured framework that aligns scientific innovation with ...
Carlo Agostoni +46 more
wiley +1 more source
Potential role of pyridostigmine in the management of pediatric chronic intestinal pseudo-obstruction in a girl with ACTL6B mutation: a case report and a review of literature. [PDF]
Rulli I +7 more
europepmc +1 more source
New cine magnetic resonance imaging parameters for the differential diagnosis of chronic intestinal pseudo-obstruction. [PDF]
Sato H +8 more
europepmc +1 more source
Abstract Acute colonic pseudo‐obstruction or Ogilvie's syndrome is an acute dilatation of the large bowel without an obstructive lesion. Symptoms include abdominal distension, nausea and vomiting, constipation, and occasional dyspnea. The disorder most commonly involves the cecum and right colon and is most frequently seen in male patients above the ...
Kirby Lampe +3 more
wiley +1 more source
Gastrointestinal malrotation and chronic intestinal pseudo-obstruction in two pediatric patients with Baraitser-Winter cerebrofrontofacial syndrome. [PDF]
Lee V +4 more
europepmc +1 more source
Abstract Multiple Endocrine Neoplasia type 2B (MEN2B) is a rare hereditary cancer syndrome characterized by medullary thyroid carcinoma, mucosal neuromas, and pheochromocytoma. Gastrointestinal involvement is common and often manifests as diffuse intestinal ganglioneuromatosis (IGN), which can impair motility and lead to severe constipation, pseudo ...
Aldo Majluta Yeb +2 more
wiley +1 more source

