Results 221 to 230 of about 1,268,979 (296)

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

Advanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen, Zixing Xu, Zerun Hao, Yanming Chen, Kai Xie, Haofan Yin, Xueying Wang, Jie Min, Sihan Sun, Baiding Chen, Chengxiu Ling, Mingming Xu, Yizhao Chen, Gang Ruan   +13 more
wiley   +1 more source

Screening for Chronic Kidney Disease by Mobile Health Unit Outreach.

JAMA Netw Open
Brook RD, Korzeniewski SJ, Foster B, Kurian P, Reed B, Steinberg-Abreu A, Young JL, Levy PD.   +7 more
europepmc   +1 more source

Chronic kidney disease-associated pruritus: a perspective on skin barrier damage. [PDF]

Ren Fail
Zeng F, Zhu C, Ding L, Yang B, Liu N.
europepmc   +1 more source

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

Advanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño, Víctor M. de la Oliva Roque, Javier‐Ignacio Ramirez‐Lopez, David P. Kreil, Joaquín Dopazo, Carlos Loucera   +5 more
wiley   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

CHRONIC KIDNEY DISEASE

The Professional Medical Journal, 2018
Pooran Mal, Muhammad Nadeem Ahsan, Mehwish Bukhari, Abdul Manan Junejo   +3 more
openaire   +2 more sources

Difelikefalin in Chinese patients with chronic kidney disease-associated pruritus. [PDF]

Clin Kidney J
Zuo L, Gan L, Guan T, He W, Ye H, Peng Q, Liu B, Dai H, Ba Y, Xue L, Lowe M, Enoiu M.   +11 more
europepmc   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Chronic Kidney Disease Severity and Risk of Cognitive Impairment.

JAMA Netw Open
Huang Z, Yaffe K, Li C, Xiao C, Pan Y, Sun X, Anderson AH, He J, Jaar BG, Han H, Kiryluk K, Rahman M, Rao P, Ricardo AC, Shah VO, Srivastava A, Taliercio JJ, Kurella Tamura M, Unruh ML, Weir MR, Lash JP, Bazzano LA, Chen J, Mills KT, Kelly TN, Chronic Renal Insufficiency Cohort (CRIC) Study Investigators.   +25 more
europepmc   +1 more source