Results 71 to 80 of about 1,268,979 (296)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Chronic Anticoagulation in Chronic Kidney Disease∗

open access: yesJournal of the American College of Cardiology, 2014
Bleeding in patients with chronic kidney disease (CKD) or “uremic bleeding” is a well-recognized complication. It has been described as far back as 1907 by Reisman [(1)][1], classically as a complication of Bright disease.
Ball, Timothy   +2 more
openaire   +2 more sources

Pengaruh Penyakit Ginjal Kronik Terhadap Disfungsi Ereksi Pria [PDF]

open access: yes, 2014
: Chronic kidney disease is decreased in kidney function that persistent and irreversible. Chronic kidney disease can lead to problems in the erectile function of men because of disorders on some factors, that are the endocrine system, the vascular ...
Simanjuntak, B. N. (Boni)
core  

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Emphysematous pyelonephritis in a diabetic child: a case report and review of the literature

open access: yesJournal of Medical Case Reports
Introduction Emphysematous pyelonephritis is a life-threatening condition characterized by gas accumulation within the kidney and the surrounding tissues, often resulting in tissue necrosis.
Behnaz Bazargani   +4 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

A case report of NPHP1 deletion in Chinese twins with nephronophthisis

open access: yesBMC Medical Genetics, 2020
Background Nephronophthisis (NPHP) is a rare autosomal recessive inherited disorder with high heterogeneity. The majority of NPHP patients progress to end-stage renal disease (ESRD) within the first three decades of life.
Feng Chen   +6 more
doaj   +1 more source

Retrospective analysis of crescent score in clinical prognosis of IgA nephropathy

open access: yesOpen Medicine, 2022
The scoring of crescents (Cs) was recently added to the Oxford classification for IgA nephropathy (IgAN). Because of the short-term use of the C score in clinical practice, its validity and applicability need to be verified. We, retrospectively, analyzed
Chen Ying   +5 more
doaj   +1 more source

Chronic kidney disease and cardiovascular risk in six regions of the world (ISN-KDDC): a cross-sectional study [PDF]

open access: yes, 2016
Background Chronic kidney disease is an important cause of global mortality and morbidity. Data for epidemiological features of chronic kidney disease and its risk factors are limited for low-income and middle-income countries.
Bikbov, Boris   +7 more
core  

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