Development of Nanoflare Nanosensors for Monitoring Cellular Insulin mRNA in Beta Cells and Islets
This study presents the design and application of In2‐NF probes for detecting insulin mRNA in beta cells and islets. Using spherical nucleic acid‐coated gold nanoparticles, the probes offer strong fluorescent signals upon hybridization. Their performance is validated across 2D and 3D cultures and rat islets, demonstrating sensitive, real‐time mRNA ...
Yana Hu +7 more
wiley +1 more source
Gabapentin Toxicity in Patients with Chronic Kidney Disease; Series of Our Cases
Gabapentin is an anticonvulsant with analgesic and anxiolytic effects and also an agent used for treatment of a variety of chronic neuropathic pains. Because gabapentin is eliminated solely through the kidney, kidney failure poses a risk for gabapentin ...
Ali KARAGÖZ +4 more
doaj
Aphasia Associated With Acute on Chronic Kidney Failure in an Adolescent. [PDF]
Jones JA +4 more
europepmc +1 more source
Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou +4 more
wiley +1 more source
CHRONIC KIDNEY DISEASE RAAS blockade and diastolic heart failure in chronic kidney disease
New data from Ahmed et al. show that discharge prescriptions for renin-angiotensin-aldosterone inhibitor therapy are associated with a significant reduction in all-cause mortality in elderly patients with diastolic heart failure and chronic kidney ...
Franssen, Casper F. M. +4 more
core +1 more source
3D‐Nanoprinted Fluidically Steerable Soft Robotic Microcatheters
This work introduces a ∼3‐French (1 mm‐in‐diameter) soft robotic microcatheter fabricated by means of two‐photon direct laser writing. The 3D‐printed microcatheter enables remote, on‐demand steering via microfluidic actuation for guidewire‐free navigation of vascular networks as well as microcatheter‐mediated delivery of fluidic payloads to target ...
Bailey M. Felix +17 more
wiley +1 more source
The Genetic Cross-Talk between Periodontitis and Chronic Kidney Failure Revealed by Transcriptomic Analysis. [PDF]
Ren D +5 more
europepmc +1 more source
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin +3 more
wiley +1 more source
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang +13 more
wiley +1 more source
Alkaptonuria in an Elderly Presenting with Asynchronous Rupture of both Quadriceps Tendons and Chronic Kidney Failure: Case Report and Literature Review. [PDF]
Issa AMA, Alsager GA.
europepmc +1 more source

