Results 121 to 130 of about 465,591 (312)

National chronic kidney disease fact sheet, 2014 [PDF]

open access: yes
Chronic kidney disease (CKD) is a condition in which your kidneys are damaged and cannot filter blood as well as healthy kidneys. Because of this, wastes from the blood remain in the body and may cause other health problems.CKD is common among adults in ...

core  

Evaluation of Variation in the Performance of GFR Slope as a Surrogate End Point for Kidney Failure in Clinical Trials that Differ by Severity of CKD

open access: yes, 2023
Background The GFR slope has been evaluated as a surrogate end point for kidney failure in meta-analyses on a broad collection of randomized controlled trials (RCTs) in CKD.
the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI)
core  

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang   +12 more
wiley   +1 more source

Cardiorenal syndrome

open access: yesSouthwest Respiratory and Critical Care Chronicles, 2013
Cardiovascular disease is the leading cause of death in patients with chronic kidney disease.  Heart failure may lead to acute kidney injury and vice versa. Chronic kidney disease may affect the clinical outcomes in patients with cardiovascular disorders.
Sabry Omar, Ahmed Zedan
doaj  

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

open access: yesAdvanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su   +10 more
wiley   +1 more source

Epidemiology of Chronic Kidney Failure

open access: yesRevista Finlay
Foundation: chronic kidney disease is among the twenty leading causes of years of life lost worldwide. Objective: to determine the clinical epidemiology of chronic kidney disease in affected individuals in the municipality of Banes, Holguín province ...
Julio Armando Sánchez Delgado   +1 more
doaj  

Comparative Analysis of Biochemical Parameters Across Different Stages of Kidney Disease: From Early Kidney Disease to Dialysis-Dependent Renal Failure [PDF]

open access: yesپیاورد سلامت
Background and Aim: This study investigated the biochemical profiles of individuals with different stages of kidney disease, including those with kidney disease without hemodialysis, chronic kidney disease without hemodialysis, and individuals with renal
Nabeel Taher Jameel Alghanim   +4 more
doaj  

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