Results 121 to 130 of about 688,833 (358)

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer   +10 more
wiley   +1 more source

INDICATORS OF CYTOKINE STATUS IN INFANTS WITH PERINATAL CNS DAMAGE TO MOTHERS WITH CHRONIC PLACENTAL NSUFFICIENCY

open access: yesМедицинский вестник Юга России, 2015
Purpose: the study of cytokine status in infants with perinatal CNS damage from mothers with placental insufficiency.Materials and methods: were examined 95 newborns from mothers with chronic kidney disease.
M. A. Levkovich   +2 more
doaj   +1 more source

Penyakit Ginjal Kronis pada Anjing dan Kucing: Manajemen Terapi dan Diet [PDF]

open access: yes, 2017
Chronic kidney disease is a progressive impairment of renal function and irreversible. The kidneys fail to maintain metabolism and fluid and electrolyte balance, causing uremia.
Indarjulianto, S. (Soedarmanto)   +2 more
core   +3 more sources

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang   +9 more
wiley   +1 more source

Gambaran Kadar Kalsium Pada Pasien Penyakit Ginjal Kronik Stadium 5 Non Dialisis [PDF]

open access: yes, 2016
: Calcium is the largest mineral in the body and is necessary in most biological processes. The body\u27s calcium levels are influenced by a variety of renal disorders, one of which is chronic kidney disease.
Idris, N. A. (Nur)   +2 more
core  

p-Cresyl sulfate [PDF]

open access: yes, 2017
If chronic kidney disease (CKD) is associated with an impairment of kidney function, several uremic solutes are retained. Some of these exert toxic effects, which are called uremic toxins.
Glorieux, Griet   +3 more
core   +3 more sources

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer   +7 more
wiley   +1 more source

The alteration in peripheral neutrophils of patients with chronic kidney disease

open access: yesCurrent Issues in Pharmacy and Medical Sciences, 2015
Recent findings have demonstrated the impaired functions of neutrophils of patients with chronic renal failure. The purpose of our research was to study oxidative modified proteins, as well as the histone spectrum in neutrophils drawn from patients with ...
Yevgenyevna Muravlyova Larissa   +6 more
doaj   +1 more source

Wars, disasters and kidneys [PDF]

open access: yes, 2014
This paper summarizes the impact that wars had on the history of nephrology, both worldwide and in the Ghent Medical Faculty notably on the definition, research and clinical aspects of acute kidney injury.
Lameire, Norbert
core   +2 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

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