Results 121 to 130 of about 614,626 (358)

Randomized multicentre pilot study of sacubitril/valsartan versus irbesartan in patients with chronic kidney disease: United Kingdom Heart and Renal Protection (HARP)- III—rationale, trial design and baseline data [PDF]

, 2016
BACKGROUND: Patients with chronic kidney disease (CKD) are at risk of progression to end-stage renal disease and cardiovascular disease. Data from other populations and animal experiments suggest that neprilysin inhibition (which augments the ...
Baigent, C., Baxter, A., Bethel, A., Bowman, L., Brunskill, N., Cockwell, P., Dayanandan, R., Emberson, J., Haynes, R., Herrington, W.G., Hill, M., Judge, P.K., Kalra, P.A., Knott, C., Landray, M.J., McMurray, John J., Murphy, K., Roderick, P., Staplin, N., Storey, B.C., Taal, M., Tomson, C., Wheatley, K., Wheeler, D.C.   +23 more
core   +1 more source

Highly Sensitive Cuffless Blood Pressure Monitoring with Selective Laser‐Sintered Liquid Metal Conductors

Advanced Functional Materials, EarlyView.
A soft, compact, and cuffless system for continuous blood pressure monitoring using laser‐sintered liquid metal conductors is developed. The stretchability and sensitivity of the device enable real‐time, non‐invasive tracking of blood pressure, including recovery after exercise. This wearable device offers a practical solution for managing hypertension
Jung Jae Park, Sangwoo Hong, Yeongju Jung, Phillip Won, Carmel Majidi, Minwoo Kim, Seung Hwan Ko   +6 more
wiley   +1 more source

The alteration in peripheral neutrophils of patients with chronic kidney disease

Current Issues in Pharmacy and Medical Sciences, 2015
Recent findings have demonstrated the impaired functions of neutrophils of patients with chronic renal failure. The purpose of our research was to study oxidative modified proteins, as well as the histone spectrum in neutrophils drawn from patients with ...
Yevgenyevna Muravlyova Larissa, Molotov-Luchankiy Vilen Borisovich, Yemelyevna Bakirova Ryszhan, Akylbekovna Turmukhambetova Anar, Anatolyevich Klyuyev Dmitriy, Andreevna Demidchik Ludmila, Alexandrovna Kolesnikova Yevgeniya   +6 more
doaj   +1 more source

Prognostic robustness of serum creatinine based AKI definitions in patients with sepsis: a prospective cohort study [PDF]

, 2015
Background: It is unclear how modifications in the way to calculate serum creatinine (sCr) increase and in the cut-off value applied, influences the prognostic value of Acute Kidney Injury (AKI).
Dhondt, Annemieke, Lameire, Norbert, Van Biesen, Wim, Vanholder, Raymond, Vanmassenhove, Jill   +4 more
core   +2 more sources

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

Aphasia Associated With Acute on Chronic Kidney Failure in an Adolescent. [PDF]

Cureus, 2023
Jones JA, Cason RK, Chambers ET, Pizoli CE, Kumar KR.   +4 more
europepmc   +1 more source

Prevalence and correlates of depression among maintenance hemodialysis patients in Huhhot region， China： a cross-sectional study

Linchuang shenzangbing zazhi, 2022
ObjectiveTo explore the prevalence of depression in maintenance hemodialysis （MHD） patients in Huhhot， China and identify its independent related factors.MethodsFor this cross-sectional study， from July 2020 to October 2020， 315 MHD patients on ...
Zhang Yuan, Niu Jia-le, Qin Hua, Huang Liang-liang, Zhang Xiao-jun, Yu Lei, Yu Hong-yan, Yan Tao, Zhao Jian-rong, Meng Yan   +9 more
doaj  

INDICATORS OF CYTOKINE STATUS IN INFANTS WITH PERINATAL CNS DAMAGE TO MOTHERS WITH CHRONIC PLACENTAL NSUFFICIENCY

Медицинский вестник Юга России, 2015
Purpose: the study of cytokine status in infants with perinatal CNS damage from mothers with placental insufficiency.Materials and methods: were examined 95 newborns from mothers with chronic kidney disease.
M. A. Levkovich, V. A. Lindе, Т. G. Plakhotya   +2 more
doaj   +1 more source

Dual‐Nanoparticle Engineered Hydrogel Reverses Bicellular Oxidative Stress to Accelerate Diabetic Fracture Healing

Advanced Functional Materials, EarlyView.
CD105‐LNPs and PS‐LNPs can deliver α‐lipoic acid to bone marrow mesenchymal stem cells and bone marrow‐derived macrophages, reversing high glucose‐induced oxidative stress while enhancing osteogenesis and M2 polarization. Integrating both nanoparticles into glucose‐responsive hyaluronic acid hydrogel forms DLNPs@HA hydrogel, which accelerates diabetic ...
Yanzhi Zhao, Weixian Hu, Shengming Zhang, Yuheng Liao, Kangkang Zha, Chenyan Yu, Zhenhe Zhang, Wenqian Zhang, Bobin Mi, Faqi Cao, Guohui Liu, Wu Zhou   +11 more
wiley   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source