Results 171 to 180 of about 272,468 (312)

Association of chronic kidney graft failure with recipient blood pressure

, 1998
Gerhard Opelz, T. Wujciak, Eberhard Ritz, for the Collaborative Transplant Study   +3 more
openalex   +1 more source

IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation

Advanced Science, EarlyView.
LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu, Qing Lu, Zixuan Fan, Jiahui Lin, Nan He, Xin Zhang, Zhaoya Han, Tingting Zhu, Zhenzhen Wu, Yingying Xu, Yuming Wang   +10 more
wiley   +1 more source

Association of chronic kidney disease with outcomes in chronic heart failure: a propensity-matched study [PDF]

, 2008
Ruth Campbell, Xuemei Sui, Gerasimos Filippatos, T. E. Love, Claudia Wahle, Paul W. Sanders, Ali Ahmed   +6 more
openalex   +1 more source

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

Antioxidant Enzyme Gene Expression in Rats with Remnant Kidney Induced Chronic Renal Failure

, 2000
Christiane Van Den Branden, Bart Ceyssens, Dirk De Craemer, Pieter De Bleser, Karine Hellemans, Albert Geerts, D. Verbeelen   +6 more
openalex   +2 more sources

71-Year-Old Man With Chronic Kidney Failure and Sudden Change of Mental Status [PDF]

, 2009
Aaron S. Mansfield, Qi Qian
openalex   +1 more source

Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization

Advanced Science, EarlyView.
This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan, Donghui Chen, Shuangna Zhang, Chaofan Li, Qingyun Fang, Dinghua Chen, Jiabao Liu, Xin Jiang, Yingjie Zhang, Wanjun Shen, Guangyan Cai, Xiangmei Chen, Ping Li   +12 more
wiley   +1 more source

Chronic Kidney Disease – Where Next? : Predicting Outcomes And Planning Care Pathways [PDF]

, 2014
Peer reviewedPublisher ...
Black, Corri, Fluck, Nicholas, Marks, Angharad   +2 more
core   +1 more source

The Effect of Renin-Angiotensin System Inhibition on All-Cause Mortality in Hospitalized Elderly Systolic Heart Failure Patients with Chronic Kidney Disease [PDF]

, 2009
Ali Ahmed, Michael W. Rich, Richard M. Allman, Inmaculada Aban, Paul W. Sanders, Louis J. Dell’Italia, Donna K. Arnett, Thomas E. Love, George L. Bakris   +8 more
openalex   +1 more source

Tumor Microenvironment Triggered In Situ Coagulation of Supramolecularly Engineered Platelets for Precise Tumor Embolization

Advanced Science, EarlyView.
Occlusion of tumor blood vessels represents a promising yet challenging approach in cancer treatment. Herein, supramolecularly engineered platelets conjugated with morphology‐transformable nanoparticles is developed for precise tumor embolization. The engineered platelets actively accumulate at tumor sites following induced blood vessel injury.
Junyan Li, Ziyi Wang, Ruifeng Luo, Xingping Quan, Hong U Fong, Qian Cheng, Jianwen Wei, Leo Wang, Yonghua Zhao, Ruibing Wang   +9 more
wiley   +1 more source