Results 211 to 220 of about 688,833 (358)

Okanin Suppresses the Growth of Colorectal Cancer Cells by Targeting at Peroxiredoxin 5

Advanced Science, EarlyView.
Okanin suppresses colorectal cancer growth by directly targeting PRDX5. This natural compound selectively binds peroxiredoxin 5 (PRDX5), inhibiting its activity and inducing WSB1‐mediated degradation. PRDX5 loss elevates ROS, suppresses GPX4 via SIAH2, and further triggers cell death (apoptosis and ferroptosis).
Ji Zhong Zhao, Yuan Fei Li, Fu Kang Yuan, Meng Lu Zhao, Ya Wen Han, Jia Xin Wang, Qi Yang, Han Ying Ye, Yu Cheng Lu, Shao Chin Lee   +9 more
wiley   +1 more source

HEPCIDIN, IRON STATUS AND RENAL FUNCTION IN CHRONIC RENAL FAILURE, KIDNEY TRANSPLANTATION AND HEMODIALYSIS.

, 2006
NULL AUTHOR_ID
openalex   +1 more source

Advanced Microfluidics for Single Cell‐Based Cancer Research

Advanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela, Miguel Xavier   +10 more
wiley   +1 more source

WCN24-651 PREVALENCE OF STAGE 3-5 CHRONIC KIDNEY DISEASE IN A FRENCH PACIFIC REMOTE ISLAND (NEW CALEDONIA)

Kidney International Reports
Jean-François CANTIN, ELODIE MAGNAT, MARINA CAUCHY, RAPHAEL COHEN, NOEMIE BAROUX, PASCALE DOMINGUE MENA   +5 more
doaj   +1 more source

PRDM16 Reduces Cellular Senescence by Upregulating GSTM1

Advanced Science, EarlyView.
Cellular senescence drives aging and aging‐related organ disorders, yet PRDM16's role remains unexplored. This work uncovers that PRDM16 decreases significantly in aged organs, while its loss accelerates cellular senescence and aging‐related organ injury.
Qian Yuan, Yuting Zhu, Ben Tang, Yaru Xie, Mingcun Hu, Hua Su, Youhua Liu, Chun Zhang   +7 more
wiley   +1 more source

Effect of evidence-based nursing supervision on hemodialysis patients with chronic kidney failure. [PDF]

Medicine (Baltimore)
Ren W, Chen Z, Liu X, Zhu X.
europepmc   +1 more source

Nephroprotective effects of ethanolic root extract of Azima tetracantha lam in adenine-induced chronic kidney failure in Wistar rats.

Indian J Pharmacol, 2021
Arunachalam R, Rao Konda VG, Eerike M, Radhakrishnan AK, Devi S.   +4 more
europepmc   +1 more source

The risk of acute renal failure in patients with chronic kidney disease

, 2008
Chi‐yuan Hsu, Juan D. Ordoñez, Glenn M. Chertow, Dongjie Fan, Charles E. McCulloch, Alan S. Go   +5 more
openalex   +1 more source

Chronic Kidney Disease and Outcomes in Heart Failure With Preserved Versus Reduced Ejection Fraction [PDF]

, 2013
David H. Smith, Micah L. Thorp, Jerry H. Gurwitz, David D. McManus, Robert J. Goldberg, Larry A. Allen, Grace Hsu, Sue Hee Sung, David J. Magid, Alan S. Go   +9 more
openalex   +1 more source

The Pathogenic Roles of Local Vitamin D Metabolism Defect in Valve Inflammation and Calcification

Advanced Science, EarlyView.
This study identifies the valvular interstitial cell populations responsible for valvular calcification induced by hyperphosphatemia and likely aging, uncovers local vitamin D metabolism defect‐induced inflammation as a critical pathogenic factor of calcific aortic valve disease, and highlights active vitamin D and ERK inhibitor as potential preventive
Ruichen Yang, Chong Han, Yangli Xie, Shoutao Qiu, Shaoyang Zhang, Jingjia He, Zejian Wang, Zhenlin Zhang, Huijuan Liu, Lin Chen, Baojie Li   +10 more
wiley   +1 more source