Results 211 to 220 of about 614,626 (358)

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

Non obstructive azoospermia as the only indicator of focal segmental glomerulosclerosis and chronic kidney failure: A case report. [PDF]

Urol Case Rep
Kaiyal RS, Aslih H, Sgayer I, Lowenstein L, Shlush E.   +4 more
europepmc   +1 more source

The risk of acute renal failure in patients with chronic kidney disease

, 2008
Chi‐yuan Hsu, Juan D. Ordoñez, Glenn M. Chertow, Dongjie Fan, Charles E. McCulloch, Alan S. Go   +5 more
openalex   +1 more source

Safety and tolerability of the novel non-steroidal mineralocorticoid receptor antagonist BAY 94-8862 in patients with chronic heart failure and mild or moderate chronic kidney disease: a randomized, double-blind trial [PDF]

, 2013
Bertram Pitt, Lars Køber, Piotr Ponikowski, Mihai Gheorghiade, Gerasimos Filippatos, Henry Krum, Christina Nowack, Peter Kolkhof, So Young Kim, Faı̈ez Zannad   +9 more
openalex   +1 more source

Unraveling the Role of MDK‐SDC4 Interaction in Pancreatic Cancer‐Associated New‐Onset Diabetes by Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
Midkine (MDK) is a mediator of the interaction between pancreatic cancer and beta cells. MDK, which originated from pancreatic ductal adenocarcinoma cells, exerted deleterious effects on paraneoplastic beta cells by binding to the SDC4 receptor on the beta cell surface and subsequently downregulating the Ras signaling pathway, thereby impairing insulin
Zengyu Feng, Jianyao Lou, Chuanshuai Lin, Haocheng Yu, Yuheng Tu, Jiali Gong, Xiawei Li, Yulian Wu   +7 more
wiley   +1 more source

The role of genomic disorders in chronic kidney failure of undetermined aetiology ≤50 years. [PDF]

Clin Kidney J
Granhøj J, Pedersen KV, Aagaard MM, Graakjaer JA, Lildballe DL, Birn H, Rasmussen M.   +6 more
europepmc   +1 more source

Chronic Kidney Disease and Outcomes in Heart Failure With Preserved Versus Reduced Ejection Fraction [PDF]

, 2013
David H. Smith, Micah L. Thorp, Jerry H. Gurwitz, David D. McManus, Robert J. Goldberg, Larry A. Allen, Grace Hsu, Sue Hee Sung, David J. Magid, Alan S. Go   +9 more
openalex   +1 more source

LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing

Advanced Science, EarlyView.
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang, Yuehui Xi, Qiaojun Fang, Sai Shi, Fei Wang, Fuyu Xian, Zhongyang Zhang, Yuxin Yang, Xishuo Jin, Xiaomin Wang, Chen Cao, Hailin Zhang, Nikita Gamper, Zhigang Xu, Haitao Shen, Ping Lv   +15 more
wiley   +1 more source

Determining the frequency of Helicobacter pylori in children with chronic kidney failure and its relationship to gastrointestinal symptoms. [PDF]

Clin Case Rep
Nezhad BN, Allahverdi B, Motamed F, Djalalinia S, Askarian F, Fahimi D, Bazargani B, Abbasi A, Moghtaderi M.   +8 more
europepmc   +1 more source

Modeling of Oxidized PTH (oxPTH) and Non-oxidized PTH (n-oxPTH) Receptor Binding and Relationship of Oxidized to Non-Oxidized PTH in Children with Chronic Renal Failure, Adult Patients on Hemodialysis and Kidney Transplant Recipients [PDF]

, 2013
Berthold Hocher, Dominik Oberthür, Torsten Slowinski, Uwe Querfeld, Franz Schaefer, Anke Doyon, Martin Tepel, Heinz Jürgen Roth, Hans Jürgen Grön, Christoph Reichetzeder, Christian Betzel, Franz Paul Armbruster   +11 more
openalex   +1 more source