Results 101 to 110 of about 2,356,863 (206)

Prostanoids in patients with diabetes and chronic limb-threatening ischemia: a meta-analysis of randomized clinical trials for the development of the Italian guidelines for the treatment of diabetic foot syndrome

The incidence and prevalence of chronic limb-threatening ischemia (CLTI) are dramatically increasing among patients with diabetes [1]. CLTI is characterized by the presence of rest pain, gangrene, or lower limb ulceration > 2 weeks duration [1]
Scevola G., Uccioli L., Bordieri C., Tramonta R., Silverii A., Monge L., Miranda C., Scatena A., Monami M., De Cassai A., Lorenzoni V., Gargiulo M., Bernetti A., Medea G., Stefanon L., Cappella C., Volpe A., Stabile E., Vermigli C., Falcone M., Ragghianti B.   +20 more
core   +1 more source

Influence of age on the development of stress hyperglycemia during first‐onset ST‐elevation myocardial infarction

Journal of Diabetes Investigation, EarlyView.
Among 8,779 non‐diabetic patients with first‐onset STEMI, older age was associated with a higher likelihood of stress hyperglycemia. However, the excess mortality risk associated with stress hyperglycemia was greatest in younger patients and attenuated with advancing age, highlighting the possibility of age‐dependent prognostic significance.
Hon Jen Wong, Joy Xin Yi Au, Yao Hao Teo, Yao Neng Teo, Chen Ee Low, Chun En Yau, Norman H.Y. Lin, Pei Chia Eng, Li Feng Tan, Reshma A. Merchant, Ping Chai, Anand Adinath Ambhore, James W. L. Yip, Andrew Fu‐Wah Ho, David Foo, Pow‐Li Chia, Patrick Zhan‐Yun Lim, Khung Keong Yeo, Weien Chow, Daniel Thuan Tee Chong, Derek J. Hausenloy, Mark Y. Y. Chan, Ching‐Hui Sia   +22 more
wiley   +1 more source

Clinicogenetic Characterization of H Syndrome in a South African Child

Pediatric Dermatology, EarlyView.
ABSTRACT H syndrome is a rare autosomal recessive genodermatosis caused by loss‐of‐function SLC29A3 variants, combining hyperpigmented indurated plaques and hypertrichosis with life‐threatening autoinflammation. We report a 5‐year‐old South African girl of first‐cousin parents who presented with hyperinflammation mimicking macrophage activation ...
Tshimogo Tswelopele Sathekge, Claude Bailly   +1 more
wiley   +1 more source

PCSK9-Inhibition to Quench Vascular Injury in Chronic Limb Threatening Ischemia∗

JACC: Basic to Translational Science, 2023
Ross Okazaki, MD, Naomi M. Hamburg, MD, MS   +1 more
doaj   +1 more source

Neutrophil-to-Lymphocyte Ratio – Risk of Amputation and Mortality in Patients with Limb-Threatening Ischemia – a Systematic Review

Journal of Cardiovascular Emergencies
Acute limb ischemia (ALI) and chronic limb-threatening ischemia (CLTI) are severe vascular conditions that can be lethal. The inflammatory response in these diseases, characterized by increased levels of neutrophils and platelets, highlights the ...
Lăpădatu Bogdan Ioan, Russu Eliza
doaj   +1 more source

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

Experimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler, Pedro Rojas‐Morales, Roman‐Ulrich Müller   +2 more
wiley   +1 more source

A Comparative Analysis of Modifiable Risk Factors for Chronic Limb-threatening Ischemia

Indian Journal of Vascular and Endovascular Surgery
Aim: The purpose of the present study is to identify modifiable risk factors causing chronic limb-threatening ischemia (CLTI). On the basis of the findings, we believe that early detection of the modifiable risk factors and its timely management will be ...
Shreya Manojbhai Poshiya, Jayeshkumar Patel   +1 more
doaj   +1 more source

Small muscle mass aerobic exercise in health and disease: Unique insights into muscle vascular and metabolic control and performance

Experimental Physiology, EarlyView.
Abstract Studies of small muscle mass exercise (SMME) have revealed that the peripheral O2 transport–utilization cascade is a dynamically regulated system in which perfusive and diffusive components can be selectively amplified, redistributed and mechanically limited depending on contraction pattern, recruitment strategy and intramuscular pressure ...
Shunsaku Koga, David C. Poole, Thomas J. Barstow, Dai Okushima, Richie P. Goulding   +4 more
wiley   +1 more source

Spinal cord stimulation trial can control pain caused by chronic limb-threatening ischemia

Background: Patients with chronic limb-threatening ischemia experience long-duration pain during ulcer treatment. Hence, painkillers are gradually increased, but adverse events often occur.
Yuta Terabe
core   +1 more source

The acute and chronic effects of local aerobic exercise on cardiovascular physiology

Experimental Physiology, EarlyView.
Abstract Exercise training has beneficial effects for primary and secondary prevention of cardiovascular disease (CVD). Effects of exercise training have typically been studied in the form of whole‐body exercise training, partly driven by the assumption that larger effects of exercise training can be achieved by involving more and larger muscle groups.
Myrthe P. F. van de Ven, Janneke Vloet, Daphne Merkus, Dick H. J. Thijssen   +3 more
wiley   +1 more source