Results 1 to 10 of about 4,104,552 (244)

The Influence of Chronic Liver Diseases on Hepatic Vasculature: A Liver-on-a-chip Review

Micromachines, 2020
In chronic liver diseases and hepatocellular carcinoma, the cells and extracellular matrix of the liver undergo significant alteration in response to chronic injury.
Alican Özkan, Danielle Stolley, Erik N. K. Cressman, Matthew McMillin, Sharon DeMorrow, Thomas E. Yankeelov, Marissa Nichole Rylander   +6 more
doaj   +3 more sources

Increased INR Values Predict Accelerating Deterioration and High Short-Term Mortality Among Patients Hospitalized With Cirrhosis or Advanced Fibrosis

Frontiers in Medicine, 2021
Background and Objective: An increase in the international normalized ratio (INR) is associated with increased mortality in patients with cirrhosis and other chronic liver diseases, while little is known about the quantitative relationship.
Ying Wang, Ying Wang, Fuchen Dong, Fuchen Dong, Shuning Sun, Shuning Sun, Xianbo Wang, Xianbo Wang, Xin Zheng, Xin Zheng, Yan Huang, Yan Huang, Beiling Li, Beiling Li, Yanhang Gao, Yanhang Gao, Zhiping Qian, Zhiping Qian, Feng Liu, Feng Liu, Xiaobo Lu, Xiaobo Lu, Junping Liu, Junping Liu, Haotang Ren, Haotang Ren, Yubao Zheng, Yubao Zheng, Huadong Yan, Huadong Yan, Guohong Deng, Guohong Deng, Liang Qiao, Liang Qiao, Yan Zhang, Yan Zhang, Wenyi Gu, Wenyi Gu, Xiaomei Xiang, Xiaomei Xiang, Yi Zhou, Yi Zhou, Baoyan Xu, Baoyan Xu, Yixin Hou, Yixin Hou, Qun Zhang, Qun Zhang, Yan Xiong, Yan Xiong, Congcong Zou, Congcong Zou, Jun Chen, Jun Chen, Zebing Huang, Zebing Huang, Xiuhua Jiang, Xiuhua Jiang, Tingting Qi, Tingting Qi, Sen Luo, Sen Luo, Yuanyuan Chen, Yuanyuan Chen, Na Gao, Na Gao, Chunyan Liu, Chunyan Liu, Wei Yuan, Wei Yuan, Xue Mei, Xue Mei, Jing Li, Jing Li, Tao Li, Tao Li, Rongjiong Zheng, Rongjiong Zheng, Xinyi Zhou, Xinyi Zhou, Weituo Zhang, Weituo Zhang, Hai Li, Hai Li, Zhongji Meng, Zhongji Meng   +85 more
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Heme oxygenase 1 alleviates nonalcoholic steatohepatitis by suppressing hepatic ferroptosis

Lipids in Health and Disease, 2023
Background Heme oxygenase 1 (HO-1) has an influential but insufficiently investigated effect on ferroptosis, which is a novel form of programmed cell death and may play an effect on nonalcoholic steatohepatitis (NASH).
Xiwei Yuan, Lu Li, Ying Zhang, Rong Ai, Dongdong Li, Yao Dou, Mengmeng Hou, Dandan Zhao, Suxian Zhao, Yuemin Nan   +9 more
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Baseline Neutrophil-to-Lymphocyte Ratio Is Independently Associated With 90-Day Transplant-Free Mortality in Patients With Cirrhosis

Frontiers in Medicine, 2021
Background: Patients with cirrhosis have an increased risk of short-term mortality, however, few studies quantify the association between neutrophil-to-lymphocyte ratio (NLR) and 90-day transplant-free mortality in cirrhotic patients.Methods: We ...
Jing Liu, Jing Liu, Hai Li, Hai Li, Jie Xia, Jie Xia, Xianbo Wang, Xianbo Wang, Yan Huang, Yan Huang, Beiling Li, Beiling Li, Zhongji Meng, Zhongji Meng, Yanhang Gao, Yanhang Gao, Zhiping Qian, Zhiping Qian, Feng Liu, Feng Liu, Xiaobo Lu, Xiaobo Lu, Junping Liu, Junping Liu, Guohong Deng, Guohong Deng, Yubao Zheng, Yubao Zheng, Huadong Yan, Huadong Yan, Liang Qiao, Liang Qiao, Xiaomei Xiang, Xiaomei Xiang, Qun Zhang, Qun Zhang, Ruochan Chen, Ruochan Chen, Jinjun Chen, Jinjun Chen, Sen Luo, Sen Luo, La Gao, La Gao, Liujuan Ji, Liujuan Ji, Jing Li, Jing Li, Xinyi Zhou, Xinyi Zhou, Haotang Ren, Haotang Ren, Sihong Lu, Sihong Lu, Sumeng Li, Sumeng Li, Weituo Zhang, Xin Zheng, Xin Zheng   +58 more
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Coagulopathy of Chronic Liver Disease [PDF]

New England Journal of Medicine, 2011
[No abstract available]
VIOLI, Francesco, FERRO, Domenico, BASILI, Stefania   +2 more
openaire   +5 more sources

Machine learning-based predictive and risk analysis using real-world data with blood biomarkers for hepatitis B patients in the malignant progression of hepatocellular carcinoma

Frontiers in Immunology, 2022
Hepatitis B Virus (HBV) infection may lead to various liver diseases such as cirrhosis, end-stage liver complications, and Hepatocellular carcinoma (HCC).
Yuemin Nan, Suxian Zhao, Xiaoxiao Zhang, Zhifeng Xiao, Ruihan Guo   +4 more
doaj   +1 more source

Avenues within the gut-liver-brain axis linking chronic liver disease and symptoms

Frontiers in Neuroscience, 2023
Symptoms of fatigue, social withdrawal and mood disturbances are commonly encountered in patients with chronic liver disease and have a detrimental effect on patient quality of life.
Henry H. Nguyen, Mark G. Swain
doaj   +1 more source

Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress

Frontiers in Molecular Biosciences, 2020
The study aimed to clarify the role and molecular mechanism of glutamate-cysteine ligase catalytic subunit (GCLC) in modulating Hepatitis C virus (HCV)-related liver fibrosis.
Na Fu, Na Fu, Dongdong Li, Dongdong Li, Wencong Li, Wencong Li, Wen Zhao, Wen Zhao, Siyu Zhang, Siyu Zhang, Lingdi Liu, Lingdi Liu, Suxian Zhao, Suxian Zhao, Jinghua Du, Jinghua Du, Lingbo Kong, Lingbo Kong, Rongqi Wang, Rongqi Wang, Yuguo Zhang, Yuguo Zhang, Yuemin Nan, Yuemin Nan   +23 more
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Dietary Copper Plays an Important Role in Maintaining Intestinal Barrier Integrity During Alcohol-Induced Liver Disease Through Regulation of the Intestinal HIF-1α Signaling Pathway and Oxidative Stress

Frontiers in Physiology, 2020
Impaired intestinal barrier function and oxidative stress injury play critical roles in the pathogenesis of alcoholic liver disease (ALD), and recent investigations have revealed a role for dietary copper in the liver and intestinal barrier function ...
Hongwei Lin, Dazhi Chen, Qianjing Du, Tongtong Pan, Hanxiao Tu, Yuedong Xu, Teng Teng, Jingjing Tu, Ji Li, Zhuo Lin, Xiaodong Wang, Lanman Xu, Yong-Ping Chen   +12 more
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Impact of Hepatic Encephalopathy on Clinical Characteristics and Adverse Outcomes in Prospective and Multicenter Cohorts of Patients With Acute-on-Chronic Liver Diseases

Frontiers in Medicine, 2021
Importance: Hepatic encephalopathy is a severe complication, and its contribution to clinical adverse outcomes in patients with acute-on-chronic liver diseases from the East is unclear.Objective: We aimed to investigate the impact of hepatic ...
Liyuan Long, Hai Li, Hai Li, Hai Li, Guohong Deng, Guohong Deng, Xianbo Wang, Xianbo Wang, Sihong Lu, Beiling Li, Zhongji Meng, Zhongji Meng, Yanhang Gao, Yanhang Gao, Zhiping Qian, Zhiping Qian, Feng Liu, Feng Liu, Feng Liu, Xiaobo Lu, Xiaobo Lu, Haotang Ren, Jia Shang, Hai Li, Shaoyang Wang, Yubao Zheng, Yubao Zheng, Huadong Yan, Huadong Yan, Shan Yin, Shan Yin, Wenting Tan, Qun Zhang, Xin Zheng, Xin Zheng, Jinjun Chen, Jinjun Chen, Sen Luo, Jinming Zhao, Wei Yuan, Tao Li, Rongjiong Zheng, Junping Liu, Xiaoxiao Liu, Wenyi Gu, Wenyi Gu, Sumeng Li, Xue Mei, Ruochan Chen, Yan Huang, Yan Huang   +50 more
doaj   +1 more source