Results 171 to 180 of about 168,862 (349)

The Global Burden of Leukemia, 1990–2021: A Systematic Analysis of Prevalence, DALYs, and Risk Factors From the Global Burden of Disease Study

Med Research, EarlyView.
Using data from the Global Burden of Disease Study 2021, we systematically assessed leukemia prevalence and disability‐adjusted life years (DALYs) across 204 countries and territories from 1990 to 2021, stratified by subtype, demographics, and risk factors.
Yuping Wu, Haini Zhang, Shuang Luo, Xiangmei Zhang, Mei Tan, Jinmei Chen, Pei Huang, Yan Chen, Zuochen Du   +8 more
wiley   +1 more source

Interferon Alfa in the treatment of B-cell chronic lymphocytic leukemia [PDF]

, 1994
Adolf, D., Bergmann, L., Dietzfelbinger, H., Emmerich, B., Knauf, W. U., Langenmayer, Irmgard, Maubach, P. A., Mitrou, P. S., Nerl, C., Thiel, E., Ziegle-Heitbrock, H. W. L.   +10 more
core   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source

A novel presentation of ocular chronic lymphocytic leukemia. [PDF]

Am J Ophthalmol Case Rep
Nakhleh LA, Keen JA, Sledz E, Chaku M, Johnson B, Ghadiali LK.   +5 more
europepmc   +1 more source

Identification of a STAT5 Target Gene, Dpf3, Provides Novel Insights in Chronic Lymphocytic Leukemia

, 2013
Marina Theodorou, Matthaios Speletas, Antigoni Mamara, Georgia Papachristopoulou, Vassiliki Lazou, Andreas Scorilas, Eleni Katsantoni   +6 more
openalex   +2 more sources

Cryptococcal Meningoencephalitis in an Immunosuppressed Patient with Chronic Lymphocytic Leukemia

, 2021
Md Monirul Hoque, Sonia Chakraborty, Arif Ahmed Khan   +2 more
openalex   +2 more sources

Loss‐of‐Function Variants in CPT1C: No Support for a Causal Role in Hereditary Spastic Paraplegia

Movement Disorders, EarlyView.
Abstract Background Hereditary spastic paraplegias (HSPs) are neurodegenerative disorders characterized by lower‐limb spasticity. Pathogenic variants in CPT1C have been implicated in HSP. Objective The objective of this study was to assess whether CPT1C loss‐of‐function (LOF) variants are causally associated with HSP.
Rui Zhu, Lang Liu, Mehrdad A. Estiar, Farnaz Asayesh, Jamil Ahmad, Meron Teferra, Grace Yoon, Mark Tarnopolsky, Kym M. Boycott, Nicolas Dupre, Patrick A. Dion, Oksana Suchowersky, Albena Jordanova, Yi‐Chung Lee, Giovanni Stevanin, Stephan Zuchner, Guy A. Rouleau, Ziv Gan‐Or   +17 more
wiley   +1 more source

Neutrophils unveiled in chronic lymphocytic leukemia. [PDF]

Front Immunol
McManus S, Khare P, Bertilaccio MTS.
europepmc   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source

The mutational landscape of small lymphocytic lymphoma compared to non-early stage chronic lymphocytic leukemia

, 2017
Alejandra Martínez‐Trillos, Magda Pinyol, Julio Delgado, Marta Aymerich, Marı́a Rozman, Tycho Baumann, Marcos González, Jesús María Hernández‐Rivas, Miguel Alcoceba, A. Muntañola, María José Terol, Blanca Navarro, Eva Giné, Pedro Jares, Sı́lvia Beà, Alba Navarro, Dolors Colomer, Ferran Nadeu, Enrique Colado, Ángel Ramírez Páyer, Tomás García-Cerecedo, Xosé S. Puente, Carlos López‐Otín, Elı́as Campo, Armando López‐Guillermo, Neus Villamor   +25 more
openalex   +2 more sources