Results 171 to 180 of about 82,620 (274)

Mutant C/EBPα p30 alleviates immunosuppression of CD8+ T cells by inhibiting autophagy‐associated secretion of IL‐1β in AML

Cell Proliferation, Volume 55, Issue 12, December 2022., 2022
Mp30 suppresses autophagy‐associated IL‐β secretion, which ultimately alleviates the immunosuppression of CD8+ T cells in the microenvironment, contributing to favourable prognosis of AML patients. Abstract Objectives Mutant C/EBPα p30 (mp30), the product of C/EBPα double mutations (DM), lacks transactivation domain 1 and has C‐terminal loss‐of ...
Jun‐Dan Wang, Jue‐Qiong Xu, Xue‐Ning Zhang, Ze‐Wei Huang, Ling‐Ling Liu, Ling Zhang, Xin‐Xing Lei, Man‐Jie Xue, Jian‐Yu Weng, Zi‐Jie Long   +9 more
wiley   +1 more source

Chronic Lymphocytic Leukemia Infiltrating in the Brain. [PDF]

Cureus
Webb LM, Kenderian SS, Angeli AM, Howard MT, Wijdicks EF.   +4 more
europepmc   +1 more source

Fludarabine: a new agent with major activity against chronic lymphocytic leukemia [PDF]

, 1989
MJ Keating, H. Kantarjian, Moshe Talpaz, J R Redman, Charles Koller, Barthel Barlogie, William S. Velasquez, William Plunkett, EJ Freireich, KB McCredie   +9 more
openalex   +1 more source

Fatty acid metabolism shapes immune responses in chronic lymphocytic leukemia. [PDF]

Biomark Res
Zhang Y, Ma J, Li P, Lu K, Han Y, Hu X, Fang X, Wang X, Zhang Y.   +8 more
europepmc   +1 more source

Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions

International Journal of Cancer, EarlyView.
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner, Jayant Y. Gadrey, Scott A. Armstrong, Michael W. M. Kühn   +3 more
wiley   +1 more source

A Distinctive Case of Hemophagocytic Lymphohistiocytosis in Chronic Lymphocytic Leukemia. [PDF]

J Investig Med High Impact Case Rep
Jayakumar J, Ginjupalli M, Khan F, Ayyazuddin M, Ashar Ali M, Isaac Coss G, Ullah A.   +6 more
europepmc   +1 more source

Phenotypes in chronic B-lymphocytic leukemia probed by monoclonal antibodies and immunoglobulin secretion studies: identification of stages of maturation arrest and the relation to clinical findings [PDF]

, 1983
J Gordon, H Mellstedt, Pierre Åman, P Biberfeld, M Bjorkholm, George Klein   +5 more
openalex   +1 more source

Epigenetic reprogramming in multiple myeloma—Challenges and opportunities

International Journal of Cancer, EarlyView.
Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar, Lev M. Kats, Emily Gruber   +2 more
wiley   +1 more source

A comprehensive review of Strongyloides stercoralis infection after solid organ and hematopoietic stem cell transplantation

Clinical Transplantation, Volume 36, Issue 11, November 2022., 2022
Abstract Background We reviewed the scientific literature to gain insight on the epidemiology and outcome of Strongyloides stercoralis infections after transplantation. Methods CINAHL, PUBMED, and OVID/MEDLINE were reviewed from inception through March 31, 2022 using key words Strongyloides and transplantation.
Cybele Lara R. Abad, Eric Bhaimia, Audrey N. Schuetz, Raymund R. Razonable   +3 more
wiley   +1 more source

Genomic characterization of chronic lymphocytic leukemia in patients of African ancestry. [PDF]

Blood Cancer J
Bonolo de Campos C, McCabe CE, Bruins LA, O'Brien DR, Brown S, Tschumper RC, Allmer C, Zhu YX, Rabe KG, Parikh SA, Kay NE, Yan H, Cerhan JR, Allan JN, Furman RR, Weinberg JB, Brander DM, Jelinek DF, Chesi M, Slager SL, Braggio E.   +20 more
europepmc   +1 more source