Results 151 to 160 of about 1,913,070 (304)

Osmotic Remodeling of Extracellular Vesicles for Precision Nanomedicine

Small, EarlyView.
Hypotonic lysis in bidistilled water is used to remodel B lymphocyte–derived extracellular vesicles into cargo‐depleted, structurally preserved nanovesicles. The process reduces intraluminal proteins and nucleic acids, reshapes membrane composition, and enhances tumor‐cell uptake in vitro, while allowing proof‐of‐concept reloading with exogenous agents,
Francesca Susa, Lorenzo Arnaboldi, Veronica De Giorgis, Marco Ghirimoldi, Elettra Barberis, Marco Brucale, Francesco Valle, Mario Malerba, Marta Vallino, Angelo Musicò, Roberto Frigerio, Alessandro Gori, Vera Mugoni, Claudia Voena, Roberto Pisano, Fabrizio Pirri, Silvia Arpicco, Marcello Manfredi, Tania Limongi   +18 more
wiley   +1 more source

A Biomimetic Breast Tumor‐On‐Chip Platform Reveals Mesenchymal Marker Upregulation Following Gold Nanorod Photothermal Therapy

Small, EarlyView.
A biomimetic microfluidic tumor‐on‐chip platform was designed to uncover subtype‐dependent responses to nanoparticle‐mediated photothermal therapy in breast cancer spheroids. The platform establishes a physiologically relevant and controllable 3D system for precision evaluation of nanophotothermal cancer therapies.
Camila A. Salvego, Hasti Honari, Anastasiia Dubrova, Stéphanie Descroix, Martha S. Ribeiro, Aurore V. Walle, Claire Wilhelm   +6 more
wiley   +1 more source

Studying Chronic Lymphocytic Leukemia Microenvironment in the Multi Omics Era. [PDF]

Hematol Oncol
Bucci A, Notarpietro G, Apollonio B, Vegliante MC, Pappagallo SA, Mondelli P, Scattone A, Donati B, Ponzoni M, Frenquelli M, Ghia P, Minoia C.   +11 more
europepmc   +1 more source

Chronic Lymphocytic Leukemia [electronic resource] : Methods and Protocols /

This book aims to provide scientists with tools and well-researched protocols to enable their research and to facilitate further progress in this common leukemia.
SpringerLink (Online service), Malek, Sami N.editor.edthttp://id.loc.gov/vocabulary/relators/edt   +1 more
core   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

Incidence and clinical impact of absolute lymphocyte count-only progression in chronic lymphocytic leukemia. [PDF]

Blood Adv
Wu X, Shadman M, Voutsinas J, Hippe DS, Randolph TW, Ujjani CS, Crider C, Keshmiri S, Smith SD, Lynch RC, Di M, Huang JJ, Martin PS, Till BG, Gopal AK.   +14 more
europepmc   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Association between serum biomarkers and clinical stage in treatment-naïve chronic lymphocytic leukemia. [PDF]

Hematol Transfus Cell Ther
Khosravifarsani M, Parvizi S, Mohseni H, Tarbiat M, Zolfaghari B, Mostafaie M, Hosseini SF, Shafiee MA.   +7 more
europepmc   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source

Treatment of Cold Agglutinin Syndrome Secondary to Chronic Lymphocytic Leukemia With Sutimlimab and Obinutuzumab-Venetoclax. [PDF]

Case Rep Hematol
Lap CJ, Broome CM.
europepmc   +1 more source