Results 221 to 230 of about 168,862 (349)

Mapping VEXAS‐associated and rare UBA1 variants in the United Kingdom: Insights from patient cohorts and the general population

British Journal of Haematology, EarlyView.
VEXAS syndrome is a late‐onset inflammatory disorder with rheumatological and haematological features. Epidemiological studies of VEXAS syndrome so far have been limited. Analysis of various UK cohorts estimates the incidence of VEXAS to be 1.51/100 000, or 171 new cases in the population of men over the age of 50 who are being investigated for myeloid
Ana Martinez Rodriguez, Leon Chang, Dorota Rowczenio, Alexandra Smith, Ebun Omoyinmi, James A. Poulter, Andrew McGregor, Sebastian Francis, Roochi Trikha, Adam Al‐Hakim, Kar Lok Kong, David G. Kent, Helen Lachmann, Austin Kulasekararaj, Catherine Cargo, Sinisa Savic   +15 more
wiley   +1 more source

Identification of 4 autophagy-related genetic variants as risk factors for chronic lymphocytic leukemia. [PDF]

Blood Adv
Cabrera-Serrano AJ, Sánchez-Maldonado JM, Rodríguez-Sevilla JJ, Reyes-Zurita FJ, Collado R, Puiggros A, Cornejo-Calvo E, García-Martín P, Ter Horst R, Benavente Y, Jerez A, Landi S, Espinet B, Maffei R, López-Nevot MÁ, Ramos-Campoy S, González-Olmedo C, Chen-Liang TH, Moreno V, Jannus F, Marcos-Gragera R, Carretero-Fernández M, Sampaio-Marques B, Gámez I, García-Álvarez M, Camp NJ, Dierssen-Sotos T, Kamaso J, Pérez EM, Norman AD, Luppi M, Li Y, Alcoceba M, Campa D, de San José S, Marasca R, Ludovico P, Clay-Gilmour A, Canzian F, Ibañez M, Netea MG, McKay J, Casabonne D, Berndt SI, Slager SL, Sainz J.   +45 more
europepmc   +1 more source

Gene Immunotherapy of Chronic Lymphocytic Leukemia: A Phase I Study of Intranodally Injected Adenovirus Expressing a Chimeric CD154 Molecule [PDF]

, 2012
Januario E. Castro, Johanna Melo‐Cardenas, Mauricio Urquiza, Juan S. Barajas‐Gamboa, Ramin S. Pakbaz, Thomas J. Kipps   +5 more
openalex   +1 more source

The BH3‐only protein NOXA is essential for apoptosis induction by BH3‐mimetics targeting BCL2 or BCL‐XL in DLBCL

British Journal of Haematology, EarlyView.
Summary BCL2 inhibitors (BCL2i) have transformed the management of chronic lymphocytic leukaemia (CLL), but their use in more aggressive B‐cell malignancies such as diffuse large B‐Cell lymphoma (DLBCL) is complicated by the more heterogeneous nature of the disease.
Nahide Yildirim, Marius Anders, Victoria M. Smith, Sandrine Jayne, Moritz Assmann, Rebekah Jukes‐Jones, Martin J. S. Dyer, Meike Vogler   +7 more
wiley   +1 more source

Correction to "Realizing precision medicine in chronic lymphocytic leukemia: Remaining challenges and potential opportunities". [PDF]

Hemasphere
europepmc   +1 more source

Zanubrutinib as a salvage therapy for ibrutinib-resistant chronic lymphocytic leukemia: a case report. [PDF]

Front Oncol
Lv Z, Lu P, Jing C, Yi X, Wu X.
europepmc   +1 more source

Bortezomib blocks Bax degradation in malignant B cells during treatment with TRAIL [PDF]

, 2008
Adrian C. Newland, Aguilar-Santelises, Beckwith, Bosanquet, Breitschopf, Brooks, Chang, Chitambar, Chresta, Ciechanover, Clohessy, Dewson, Dohmen, Fandy, Fecker, Feng-Ting Liu, Hao, Hao, Hideshima, Hongtao Ye, Hsu, Inoue, Jia, Jia, Jia, John G. Gribben, Johnson, Kabore, Kelley, Kluin-Nelemans, Kuroda, Lashinger, Li, Li Jia, Liu, Liu, Lotan, Lundqvist, MacFarlane, McConkey, Ming-Qing Du, Mitsiades, Miyashita, Nikrad, Nishii, Pahler, Perez-Galan, Pigneux, Qin, Rudner, Samir G. Agrawal, Saxena, Sayers, Scheffner, Schmitt, Schwartz, Shah, Smolewski, Strauss, Sutheesophon, Upton, Willis   +61 more
core   +1 more source

Prognostic impact of valemetostat in relapsed/refractory adult T‐cell leukaemia‐lymphoma

British Journal of Haematology, EarlyView.
Summary The prognosis for patients with relapsed/refractory (R/R) adult T‐cell leukaemia‐lymphoma (ATL) remains dismal. Recently, valemetostat, a dual inhibitor for enhancer of zeste homologue (EZH) 1 and 2, was approved in Japan for R/R aggressive ATL. However, there is no real‐world data on the efficacy and prognosis of valemetostat.
Takafumi Shichijo, Hiro Tatetsu, Yusuke Higuchi, Toshikazu Miyakawa, Kisato Nosaka, Takahisa Nakamura, Shinya Endo, Asami Yamada, Atsushi Wada, Yuki Okamoto, Toshiro Kawakita, Hitoshi Suzushima, Masao Matsuoka, Jun‐ichirou Yasunaga   +13 more
wiley   +1 more source

Pilot evaluation of optical genome mapping in chronic lymphocytic leukemia: complementing FISH analysis. [PDF]

BMC Cancer
Erdem S, Bayrak Tokaç AG, Aday A, Karaca D, Mutlu MB, Çefle K, Yenerel MN, Öztürk Ş, Kalayoğlu Beşışık S.   +8 more
europepmc   +1 more source

Erratum to: Extensive next-generation sequencing analysis in chronic lymphocytic leukemia at diagnosis: clinical and biological correlations [PDF]

, 2016
Gian Matteo Rigolin, Elena Saccenti, Cristian Bassi, Laura Lupini, Francesca Maria Quaglia, Maurizio Cavallari, Sara Martinelli, Luca Formigaro, Enrico Lista, Maria Antonella Bardi, Eleonora Volta, Elisa Tammiso, Aurora Melandri, Antonio Urso, Francesco Cavazzini, Massimo Negrini, Antonio Cuneo   +16 more
openalex   +1 more source