Results 261 to 270 of about 1,913,070 (304)
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Current Opinion in Hematology, 1997
Much progress has been made over the past year in our understanding of the cytogenesis, biology, and therapy of chronic lymphocytic leukemia (CLL). Further definition of common cytogenetic abnormalities in CLL make it appear that the identification of a new tumor suppressor gene is close at hand.
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Much progress has been made over the past year in our understanding of the cytogenesis, biology, and therapy of chronic lymphocytic leukemia (CLL). Further definition of common cytogenetic abnormalities in CLL make it appear that the identification of a new tumor suppressor gene is close at hand.
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Familial chronic lymphocytic leukemia
Current Hematologic Malignancy Reports, 2008The role of inherited genetic factors in the etiology of chronic lymphocytic leukemia (CLL) and other B-cell lymphoproliferative disorders is now well established. Significant familial aggregation of CLL and B-cell lymphoproliferative disorders has been demonstrated, but the mode of inheritance is unknown.
Richard S, Houlston, Daniel, Catovsky
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Management of Chronic Lymphocytic Leukemia
American Society of Clinical Oncology Educational Book, 2015Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL) is usually diagnosed in asymptomatic patients with early-stage disease. The standard management approach is careful observation, irrespective of risk factors unless patients meet the International Workshop on CLL (IWCLL) criteria for “active disease,” which requires treatment.
Stephan, Stilgenbauer +2 more
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Chronic Lymphocytic Leukemia in the Dog
Journal of the American Veterinary Medical Association, 1980SUMMARY Lethargy and weight loss were associated with chronic lymphocytosis in a dog. The bone marrow was infiltrated with large numbers of small lymphocytes, similar to those appearing in blood. Clinical and laboratory examinations led to a diagnosis of chronic lymphocytic leukemia.
E M, Hodgkins, J G, Zinkl, B R, Madewell
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Familial Chronic Lymphocytic Leukemia
Seminars in Oncology, 2006The role of inherited genetic factors in the etiology of chronic lymphocytic leukemia (CLL) and other B-cell lymphoproliferative disorders (LPDs) is now well established. Significant familial aggregation of CLL and B-cell LPDs has been demonstrated, but the mode of inheritance is unknown.
Gabrielle S, Sellick +2 more
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Familial Chronic Lymphocytic Leukemia
Annals of Internal Medicine, 1969Abstract A battery of laboratory tests was applied in the study of a family with chronic lymphocytic leukemia in three sibs, the progeny of a consanguineous mating.
J F, Fraumeni, C L, Vogel, V T, DeVita
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Chronic lymphocytic leukemia in china
American Journal of Hematology, 1987AbstractChronic lymphocytic leukemia (CLL) is a very common form of leukemia among middle‐aged and elderly persons in Western countries. In the Japanese, or in those with Japanese ancestry born and living in the USA, CLL is rather rare. It is also rare in China, but convincing data to support this statement are found primarily in the Chinese literature.
D R, Boggs +3 more
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Rituximab in Chronic Lymphocytic Leukemia
Seminars in Hematology, 2010Rituximab is a class I chimeric anti-CD20 antibody that has shown efficacy in chronic lymphocytic leukemia (CLL), both as a single agent and in combination with traditional chemotherapies. The modest activity demonstrated in early studies evaluating rituximab in relapsed CLL was improved with higher doses or more dose-intensive regimens that overcame ...
Samantha M, Jaglowski, John C, Byrd
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Pentostatin in chronic lymphocytic leukemia
Expert Opinion on Drug Metabolism & Toxicology, 2008Chronic lymphocytic leukemia (CLL) is a disease that typically afflicts older individuals with a median age of diagnosis in the eighth decade of life for which treatments available now are not curative. Although purine analogue based combinations produce complete responses (CRs) in many patients, the use of these combinations has been limited by ...
Craig, Sauter +2 more
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Allotransplantation for chronic lymphocytic leukemia
Hematology, 2009AbstractEfforts to develop curative treatment strategies for chronic lymphocytic leukemia (CLL) in recent years have focused on allogeneic stem cell transplantation (alloSCT). The crucial anti-leukemic principle of alloSCT in CLL appears to be the immune-mediated anti-host activities conferred with the graft (graft-versus-leukemia effects, GVL ...
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