Anti-SARS-CoV-2 antibody response in patients with chronic lymphocytic leukemia
Leukemia, 2020 Characterizing antibody (Ab)-mediated immune response to SARS-CoV-2 is fundamental to understanding COVID-19 epidemiology, reinfection potential, and vaccine development, particularly in immunocompromised patients. The first report of SARS-CoV-2 directed
L. Roeker +7 more
semanticscholar +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Study of serum antioxidant levels in patients with acute lymphocytic leukemia and chronic myelocytic leukemia before and after vincristine intake [PDF]
مجلة التربية والعلم, 2012 The study included the determination of the antioxidants levels of acute lymphocytic leukemia and chronic myelocytic leukemia patients in Mosul city (Before and after taking vincristine (Chemical drug)).
Noha altaalib
doaj +1 more source
Rituximab in combination with high-dose methylprednisolone for the treatment of chronic lymphocytic leukemia. [PDF]
, 2009 We observed that high-dose methylprednisolone (HDMP) and rituximab was well tolerated and had promising activity when used in combination to treat patients with fludarabine-refractory chronic lymphocytic leukemia (CLL).
Bole, J +6 more
core
Ibrutinib for Chronic Lymphocytic Leukemia with TP53 Alterations.
New England Journal of Medicine, 2020 Ibrutinib in CLL with TP53 Alterations Patients with chronic lymphocytic leukemia with chromosome 17 abnormalities have a worse prognosis than those without such alterations.
I. Ahn, X. Tian, A. Wiestner
semanticscholar +1 more source
FEBS Letters, EarlyView.Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley +1 more source
Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens. [PDF]
, 2015 BackgroundTo determine differentially expressed and spliced RNA transcripts in chronic lymphocytic leukemia specimens a high throughput RNA-sequencing (HTS RNA-seq) analysis was performed.MethodsTen CLL specimens and five normal peripheral blood CD19+ B ...
A Ameur +72 more
core +1 more source
Chronic lymphocytic leukemia: 2020 update on diagnosis, risk stratification and treatment
American journal of hematology/oncology, 2019 Chronic lymphocytic leukemia (CLL) is the commonest leukemia in western countries. The disease typically occurs in elderly patients and has a highly variable clinical course.
M. Hallek
semanticscholar +1 more source
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
The effects of splenic irradiation on lymphocyte subpopulations in chronic B-lymphocytic leukemia [PDF]
, 1988 We describe the effect of splenic irradiation (SI) (0,5–1 Gy weekly) on lymphocyte subpopulations for 7 patients with progressive B chronic B-lymphocytic leukemia (B-CLL).
Aabo +24 more
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