Results 181 to 190 of about 1,936,563 (245)

Pneumomediastinum and Subcutaneous Emphysema After Rapid Mediastinal Mass Regression

open access: yes
eJHaem, Volume 7, Issue 5, October 2026.
Fahad Alsayed   +2 more
wiley   +1 more source

Immune‐Cell Dynamics in the Tumor Microenvironment: Implications for Cancer Therapy

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Immune‐cell dynamics in the tumor microenvironment converge on four major barriers to effective therapy: failed immune access, defective antigen visibility and priming, loss of effector maintenance, and suppressive tissue remodeling. These barriers emerge from local hypoxic, cytokine, metabolic, and stromal signals.
Pin Guo   +8 more
wiley   +1 more source

Ineffectiveness of immune checkpoint inhibitors in prostate cancer: is it just a question of ‘‐mabs’?

open access: yesThe Journal of Pathology, Volume 270, Issue 2, Page 139-162, October 2026.
Abstract Prostate cancer (PCa) is the second most common type of neoplasm, currently treated with a variety of therapeutic agents. Although advances in treatment over the past decade have improved overall survival, patients with advanced PCa eventually progress from hormone‐sensitive PCa to metastatic castration‐resistant PCa.
Giuseppe Schepisi   +8 more
wiley   +1 more source

Cross‐Talk Between Histamine H2 Receptor and Glucocorticoid Receptor: Potential Implications in Acute Myeloid Leukemia Treatment

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT This study investigates the impact of histamine H2 receptor activation on glucocorticoid receptor (GR)‐mediated transcriptional activity, as well as its effects on leukemic cell proliferation and chemotherapy resistance. We demonstrate that activation of the histamine H2 receptor by its specific agonist, amthamine, enhances GR transcriptional ...
Valeria Torralba‐Agu   +5 more
wiley   +1 more source

High-dimensional spectral flow cytometry uncovers progressive T-cell exhaustion and myeloid cell reprogramming in a CLL mouse model. [PDF]

open access: yesHemasphere
Briesch H   +9 more
europepmc   +1 more source

Piper nigrum Has an Antitumor Effect Through Regulation of the Phosphatidylinositol 3‐Kinase Signaling Pathway in a Murine Model of Acute Myeloid Leukemia

open access: yesPhytotherapy Research, Volume 40, Issue 10, Page 5988-6004, October 2026.
Overview of the antileukemic effects of Piper nigrum extract in AML. P. nigrum reduced leukemic cell proliferation and glycolytic metabolism through modulation of the PI3K/AKT/mTOR pathway. In vivo, treatment reduced leukemic burden, improved hematological parameters, prolonged survival, and modulated antitumor immune responses.
Natalia Murillo   +3 more
wiley   +1 more source

Persistent SARS‐CoV‐2 RNA Positivity in a Chronic Lymphocytic Leukaemia Patient for 127 Days After Disease Onset: A Case Report

open access: yesRespirology Case Reports, Volume 14, Issue 10, October 2026.
This case report presents a 69‐year‐old woman with chronic lymphocytic leukaemia who exhibited prolonged SARS‐CoV‐2 RNA positivity for 127 days despite standard treatments. This case emphasises the profound immunodeficiency in CLL patients and highlights the necessity for tailored therapeutic strategies to manage persistent COVID‐19 infections ...
Farnoosh Khamseh   +3 more
wiley   +1 more source

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