Results 21 to 30 of about 1,936,563 (245)

Chronic lymphocytic leukemia and concurrent seminoma in the same testis [PDF]

open access: yesJournal of Pathology and Translational Medicine, 2022
A 59-year-old man presented with a painless testicular mass and underwent a radical orchiectomy. The resected specimen showed a 5-cm-sized, white-yellow and homogenous solid mass in the testicular parenchyma. Histologically, the central part of the tumor
Kosuke Miyai   +3 more
doaj   +1 more source

Disease-specific complications of chronic lymphocytic leukemia in binet stage a patients [PDF]

open access: yes, 2012
Disease-specific Complications of Chronic Lymphocytic Leukemia in Binet Stage A Patients: Analysis of Immunodeficiency, Autoimmune Constellations and Infections in the CLL1-Protocol.
Kwag, Doo Young
core   +1 more source

A retinoic acid-dependent stroma-leukemia crosstalk promotes chronic lymphocytic leukemia progression

open access: yesNature Communications, 2018
The stromal microenvironment plays a key role in the expansion of chronic lymphocytic leukemia. Here, the authors use the Eµ-TCL1 mouse model to show that leukemic B-cells induce the activation of retinoic acid synthesis in stromal cells of the lymphoid ...
Diego Farinello   +27 more
doaj   +1 more source

A high number of losses in 13q14 chromosome band is associated with a worse outcome and biological differences in patients with B-cell chronic lymphoid leukemia

open access: yesHaematologica, 2009
Background Among patients with B-cell chronic lymphoid leukemia, those with 13q14 deletion have a favorable outcome. However, whether the percentage of cells with 13q- influences the prognosis or the biological characteristics of this disease is unknown.
José Ángel Hernández   +17 more
doaj   +1 more source

PrPCWD lymphoid cell targets in early and advanced chronic wasting disease of mule deer [PDF]

open access: yes, 2002
Up to 15% of free-ranging mule deer in northeastern Colorado and southeastern Wyoming, USA, are afflicted with a prion disease, or transmissible spongiform encephalopathy (TSE), known as chronic wasting disease (CWD).
Keulen, L.J.M., van   +7 more
core   +1 more source

Prevalence of Leukemia and Associated Factors among Patients with Abnormal Hematological Parameters in Jimma Medical Center, Southwest Ethiopia: A Cross-Sectional Study

open access: yesAdvances in Hematology, 2020
Introduction. Leukemia is a heterogeneous group of hematological disorder which comprise several diverse and biologically distinct subgroups. Leukemia represents the 11th and 10th most frequent cause of cancer morbidity and mortality worldwide ...
Woldeteklehaymanot Kassahun   +5 more
doaj   +1 more source

Chronic myeloid leukemia stem cells display alterations in expression of genes involved in oxidative phosphorylation [PDF]

open access: yes, 2012
The mitochondrial respiratory chain (MRC) consists of protein complexes I, II, III, IV and V that support oxidative phosphorylation (OXPHOS), which depends on electron transport to generate adenosine triphosphate (ATP).
Flis, Krzysztof   +9 more
core   +1 more source

Plasma hepatic enzymes as biopredictors of type, metastasis, and prognostication of hematological malignancies

open access: yesJournal of Medical Sciences, 2018
Background and Aim: The present study evaluated the levels of some hepatic enzymes in the plasma of Nigerians affected with hematological malignancies, to determine if these enzymes could be established as predictors of possible metastasis to the liver ...
Abdulazeez Adelaja Akinlolu   +4 more
doaj   +1 more source

Dasatinib-Induced Colitis with Rectal Sparing in a Patient with Chronic Myeloid Leukemia (Chronic Phase) on Dasatinib as an Upfront Therapy: Case Report

open access: yesCase Reports in Oncology, 2021
Dasatinib is a BCR-ABL tyrosine kinase inhibitor which was approved in 2006 for the treatment of adults diagnosed with Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) in chronic phase (CP) and accelerated (myeloid or lymphoid blast)
Zakaria Maat   +2 more
doaj   +1 more source

Epigenetic Activation of SOX11 in Lymphoid Neoplasms by Histone Modifications [PDF]

open access: yes, 2011
Recent studies have shown aberrant expression of SOX11 in various types of aggressive B-cell neoplasms. To elucidate the molecular mechanisms leading to such deregulation, we performed a comprehensive SOX11 gene expression and epigenetic study in stem ...
Amador Virginia   +107 more
core   +1 more source

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