Results 171 to 180 of about 101,301 (311)

Characteristics, therapeutic pathway and the economic burden of patients with drug‐resistant epilepsy: A real‐world analysis following the introduction of cenobamate in Italy

open access: yesEpilepsia, EarlyView.
Abstract Objectives Drug‐resistant epilepsy (DRE) remains a major clinical challenge, affecting approximately one‐third of patients with epilepsy. Cenobamate, a novel antiseizure medication (ASM) approved in Italy in 2022, has shown promise in clinical trials. However, real‐world data on its use, especially economic evaluations, remain limited.
Valentina Perrone   +27 more
wiley   +1 more source

Anti‐seizure medications in patients with post‐stroke epilepsy: A survival analysis study

open access: yesEpilepsia, EarlyView.
Abstract Objective The role of antiseizure medications (ASMs) in patients with post‐stroke epilepsy (PSE) is still debated. Although a few studies have compared the efficacy of different ASMs on mortality in patients with PSE, overall evidence on the impact of ASM use on survival is limited.
Ippazio Cosimo Antonazzo   +9 more
wiley   +1 more source

Extracellular vesicle proteomics identifies novel blood biomarkers for the early diagnosis of status epilepticus

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to identify novel blood‐based biomarkers associated with the early diagnosis of status epilepticus (SE) by exploring proteomic alterations in plasma extracellular vesicles (EVs). Methods We conducted an observational and prospective study in a two‐phase design: a discovery proteomic analysis of plasma EVs ...
Estevo Santamarina   +11 more
wiley   +1 more source

Spreading depolarization and its influence on epileptiform activity

open access: yesEpilepsia, EarlyView.
Abstract Spreading depolarization (SD) is a transient disruption of electrographic activity that slowly propagates through the gray matter by chemical contiguity, and it is characterized by a large depolarization of neurons and glial cells. SD, which is associated with massive changes in ion homeostasis, including extreme increases in [K+]o, was shown ...
Maxime Lévesque   +2 more
wiley   +1 more source

Improving the detection of chronic migraine: Development and validation of Identify Chronic Migraine (ID-CM)

open access: hybrid, 2015
Richard B. Lipton   +15 more
openalex   +1 more source

BDNF gene polymorphysm RS2049046 in episodic and chronic migraine [PDF]

open access: gold, 2013
Yu. É. Azimova   +2 more
openalex   +1 more source

Gray Matter Structural Alterations in Chronic and Episodic Migraine: A Morphometric Magnetic Resonance Imaging Study [PDF]

open access: bronze, 2020
Álvaro Planchuelo‐Gómez   +5 more
openalex   +1 more source

Proposed criteria of levels of evidence for co‐occurring epilepsy in people with functional/dissociative seizures

open access: yesEpilepsia, EarlyView.
Abstract Objective This work was undertaken to describe the level of evidence for co‐occurring epileptic seizures in patients with known functional/dissociative seizures (FDS) using stratification criteria analogous to the International League Against Epilepsy criteria for functional seizures.
Shruti N. Iyer   +16 more
wiley   +1 more source

Safety and Efficacy of 10 kHz Spinal Cord Stimulation for the Treatment of Refractory Chronic Migraine: A Prospective Long‐Term Open‐Label Study

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Background Refractory chronic migraine (rCM) is a highly disabling condition for which novel safe and effective treatments are needed. Safety and long‐term efficacy of paresthesia‐free high cervical 10 kHz spinal cord stimulation (SCS) were here prospectively evaluated for the treatment of rCM.
Adnan Al‐Kaisy   +7 more
wiley   +1 more source

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