Results 191 to 200 of about 2,830,257 (398)

Practical Insights on the Identification and Management of Patients with Chronic Migraine [PDF]

open access: gold, 2022
Andrew Blumenfeld   +5 more
openalex   +1 more source

Leukoencephalopathy, a Frequent Complication After High‐Dose Methotrexate in Treatment of Osteosarcoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Methotrexate‐associated leukoencephalopathy is poorly documented in osteosarcoma. Since 2007, our institution has monitored osteosarcoma patients with sequential magnetic resonance imaging (MRI) and neuropsychological evaluations during treatment and follow‐up.
Sandra Raimbault   +13 more
wiley   +1 more source

Predicting Pharmacological Treatment Response in Migraine Using AI/ML: A Scoping Review of the Evidence and Future Directions

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.
ABSTRACT The treatment of migraine is hampered by inter‐individual variability, leading to an inefficient “trial and error” approach. Artificial intelligence (AI) and machine learning (ML) offer a path towards precision medicine by predicting therapeutic outcomes.
Martina Giacon, Salvatore Terrazzino
wiley   +1 more source

Relief of pain associated with spasticity in adult patients after treatment with onabotulinumtoxinA: Post hoc observational results from the ASPIRE study

open access: yesPM&R, EarlyView.
Abstract Background Pain is often observed in patients with spasticity, but little is known about the relationship between pain and spasticity and the effectiveness of treating pain with botulinum toxins in these patients. Objective To explore onabotulinumtoxinA (onabotA) use and pain relief in patients with spasticity with pain at baseline.
Jörg Wissel   +5 more
wiley   +1 more source

Chronic Migraine: Diagnosis, Characteristics, Lifestyle Modification, Trigger Reduction and Treatment

open access: yesJournal of Pharmacy and Bioallied Sciences
The most prevalent brain condition that impairs function is migraine. A chronic migraine is a very incapacitating disorder that is defined by having a migraine that lasts for at least 10 days every month.
Roshan Kumar Jha   +3 more
doaj   +1 more source

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen   +6 more
wiley   +1 more source

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