Results 171 to 180 of about 57,892 (307)

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Glucose dysregulation and glycemic phenotyping in chronic migraine. [PDF]

Front Neurol
Nelson CA, Reavely KW, Jennings MR, Burger BJ, Kim AC, Sant DW, Bills KB.   +6 more
europepmc   +1 more source

Gβγ subunit activation of KV7 and BKCa channels underlies calcitonin gene‐related peptide vasorelaxation in myogenic rat coronary resistance arteries

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose CGRP is a potent, clinically relevant coronary vasodilator known to play a role in cardioprotection. Here, we investigated the precise intracellular signalling pathways leading to vasodilation in small coronary arteries.
Lucy A. Donovan, JinHeng Lin, Milind Khashu, Christopher J. Garland, Kim A. Dora   +4 more
wiley   +1 more source

Sleep psychoeducation strategies for patients with chronic migraine and sleep quality complaints. [PDF]

Arq Neuropsiquiatr
Andreis DG, Rodrigues MLF, Zanatta A, Marchioro IJM, Kowacs PA.   +4 more
europepmc   +1 more source

Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley   +1 more source

Single-Nucleus RNA-Seq Reveals Neuroprotective Effects of Acupuncture in Chronic Migraine Through Modulation of Glial Subtypes. [PDF]

CNS Neurosci Ther
Sun S, Hu S, Sun M, Tang Z, Wang Y, Xu L, Cao P, Liu L, Wang R, Yuan J, Chen Y, Zhao L.   +11 more
europepmc   +1 more source

Chronic migraine [PDF]

Neurologie pro praxi, 2019
openaire   +1 more source

The mechanism of different microglial receptors mediating central inflammation in chronic migraine: a meta-analysis. [PDF]

J Headache Pain
Lin X, Yu W, Lou J, Cao Z, Song W.
europepmc   +1 more source

Long‐term neurological and psychiatric outcomes after paediatric arterial ischaemic stroke and cerebral sinovenous thrombosis

Developmental Medicine &Child Neurology, EarlyView.
Arterial ischemic stroke (AIS) or cerebral sinovenous thrombosis (CSVT) is a rare but serious event in children and adolescents. A descriptive long‐term (median 16 years) follow‐up study of patients revealed an increased risk of neurological and psychiatric diagnoses after AIS or CSVT, highlighting significant morbidity compared with the general ...
Jeanette Soenderlyng Springer, Søren Paaske Johnsen, Charlotte Olesen, Jan Brink Valentin, Ruta Tuckuviene   +4 more
wiley   +1 more source

Iron concentration in the ventral pallidum of chronic migraine with medication-overuse headache. [PDF]

J Headache Pain
Xu X, He J, Zhou M, Wu X, Zhao F, Fu J, Luo X, Li K, Zeng Q, Wang C, Guan X, Huang P, Zhang M, Liu K.   +13 more
europepmc   +1 more source