Results 1 to 10 of about 138,819 (251)

Central sensitization in episodic and chronic migraine [PDF]

Headache Medicine, 2020
Introduction In chronic migraine, central sensitization (CS) may play a significant pathophysiological role, since it amplifies pain signals, causing increased pain and disability.
Marco Antonio Nihi, Paulo Sergio Faro Santos, Daniel Benzecry Almeida   +2 more
doaj   +2 more sources

Evaluating the efficacy of rimegepant as a preventive treatment for chronic and episodic migraine: a three-month longitudinal retrospective cohort study. [PDF]

Front Neurol
BackgroundRimegepant, an oral calcitonin gene-related peptide receptor antagonist approved for both acute and preventive migraine treatment, demonstrates efficacy in clinical trials, but real-world evidence remains limited.
Khan H, Khan MS, Khan S, Liu F, Feng Q, Ahmad I, Tan G.   +6 more
europepmc   +2 more sources

Episodic migraine is associated with a more atherogenic lipid profile rather than independent insulin resistance: a case-control study. [PDF]

Lipids Health Dis
Background Cardiometabolic factors may influence migraine biology through metabolic, inflammatory, and vascular mechanisms, but studies examining insulin resistance and dyslipidaemia in migraine have yielded inconsistent results, partly due to ...
Szabóová S, Duraníková O, Örzsik B, Glevická M, Straka I, Valkovič P.   +5 more
europepmc   +2 more sources

Association between sleep and awake bruxism in patients with migraine

Headache Medicine, 2021
Introduction When migraine undergoes transformation from episodic to chronic form it becomes more disabling due to the refractoriness in treatment and the emergence of comorbidities, with the establishment of a bidirectional relationship between sleep ...
Keryn Sporh Godk, Maria Luiza dos Santos, Marco Antonio Takashi Utiumi, João Guilherme Bochnia Küster, Luiz Carlos Canalli Filho, Nikolai José Eustátios Kotsifas, Bin Cheng Tan, Eldislei Mioto, Gabriel Eduardo Faria Colombani, Elcio Juliato Piovesan   +9 more
doaj   +1 more source

Comparison of static and dynamic balance measurements among chronic and episodic migraine patients

Arquivos de Neuro-Psiquiatria, 2021
Background: Migraine is one of the most frequent and incapacitating headaches, with a high degree of impairment of balance control and postural stability. Objective: To investigate the effects of episodic and chronic migraine on postural balance through
Seyhan Dumanlidağ, Aysel Milanlioğlu
doaj   +1 more source

Plasma level of calcitonin gene-related peptide in the diagnosis of episodic migraine with comorbid conditions

Zaporožskij Medicinskij Žurnal, 2022
Comorbid and co-occurring diseases are risk factors for the progression of episodic migraine to chronic migraine. Biomarkers for migraine could help with diagnosis and treatment selection and monitoring. Aim. To examine the role of the plasma level of
O. Ye. Dubenko, A. O. Chernenko
doaj   +1 more source

Chronic Migraine Pathophysiology and Treatment: A Review of Current Perspectives

Frontiers in Pain Research, 2021
Chronic migraine is a disabling neurological disorder that imposes a considerable burden on individual and socioeconomic outcomes. Chronic migraine is defined as headaches occurring on at least 15 days per month with at least eight of these fulfilling ...
Tiffani J. Mungoven, Luke A. Henderson, Noemi Meylakh   +2 more
doaj   +1 more source

Effect of galcanezumab on severity and symptoms of migraine in phase 3 trials in patients with episodic or chronic migraine

The Journal of Headache and Pain, 2021
Background Galcanezumab, a humanized monoclonal antibody that binds calcitonin gene-related peptide, has demonstrated a significant reduction in monthly migraine headache days compared with placebo. Here, we analyze data from 3 randomized clinical trials
Michael Ament, Kathleen Day, Virginia L Stauffer, Vladimir Skljarevski, Mallikarjuna Rettiganti, Eric Pearlman, Sheena K. Aurora   +6 more
doaj   +1 more source

The stigma of migraine. [PDF]

PLoS ONE, 2013
BACKGROUND: People who have a disease often experience stigma, a socially and culturally embedded process through which individuals experience stereotyping, devaluation, and discrimination.
William B Young, Jung E Park, Iris X Tian, Joanna Kempner   +3 more
doaj   +1 more source

Correlation of vestibular symptoms and headache in migraine patients: a clinical study of 424 cases

Di-san junyi daxue xuebao, 2021
Objective To evaluate the correlation between vestibular symptoms and headache in patients with migraine, and to explore the diagnostic value of vestibular symptoms in migraine.
LIU Juan, PAN Qi, ZHANG Yun, FAN Yulan, FAN Xiaoping, ZHANG Yixin, ZHOU Jiying   +6 more
doaj   +1 more source