Клинический разбор в общей медицине, 2023 Background. Menstrual related migraine (MRM) occurs in 60% of women with migraine. These attacks are characterized by high intensity and poor response to abortive and prophylactic treatment.
Anna V. Berdnikova +4 more
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Advances in CGRP monoclonal antibodies as migraine therapy: A narrative review
Saudi Journal of Medicine and Medical Sciences, 2023 Migraine is a potentially disabling disorder, yet it remains underdiagnosed and undertreated. The release of the neuropeptide calcitonin gene-related peptide (CGRP) in the trigemino-cerebrovascular system plays a vital role in the evolution of migraine ...
Suruchi Aditya, Aditya Rattan
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Serum calcitonin gene related peptide (CGRP) levels in migraine: A study on its clinical correlation and diagnostic efficacy [PDF]
Romanian Journal of Neurology, 2021 Migraine is a primary headache disorder marked by recurrent unilateral headache episodes. Calcitonin gene related peptide (CGRP) plays major role in migraine pathophysiology.
Sofia Khatoon +7 more
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The Management of High-Frequency Episodic and Chronic Migraines with Calcitonin Gene-Related Peptide Monoclonal Antibody [PDF]
Анналы клинической и экспериментальной неврологии, 2023 Introduction. High prevalence of migraine and its impact on quality of life requires the development of original agents. In 2020, fremanezumab, a new calcitonin gene-related peptide monoclonal antibody was authorized in Russia.
Larisa A. Dobrynina +4 more
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Calcitonin receptor-like receptor is expressed on gastrointestinal immune cells [PDF]
, 2002 Background/Aims: Pharmacological and morphological studies suggest that the gut mucosal immune system and local neuropeptide-containing neurones interact.
Göke, B. +5 more
core +1 more source
The role of ECL2 in CGRP receptor activation: a combined modelling and experimental approach [PDF]
, 2013 The calcitonin gene-related peptide (CGRP) receptor is a complex of a calcitonin receptor-like receptor (CLR), which is a family B G-protein-coupled receptor (GPCR) and receptor activity modifying protein 1.
Alex C. Conner +13 more
core +2 more sources
Recent advances in targeting calcitonin gene-related peptide for the treatment of menstrual migraine
Medicine, 2022 . Menstrual migraine (MM) has a longer duration and higher drug resistance than non-perimenstrual migraine. Calcitonin gene-related peptide (CGRP) and CGRP receptors are expressed in the peripheral and central nervous systems throughout the ...
Yan Jiang, MMed, Zhen-Lun Huang, BMed
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Triptans and CGRP blockade - impact on the cranial vasculature [PDF]
, 2017 The trigeminovascular system plays a key role in the pathophysiology of migraine. The activation of the trigeminovascular system causes release of various neurotransmitters and neuropeptides, including serotonin and calcitonin gene-related peptide ...
Alejandro Labastida-Ramírez +9 more
core +3 more sources
Structural and molecular characteristics of axons in the long head of the biceps tendon [PDF]
, 2020 The innervation of the long head of the biceps tendon (LHBT) is not sufficiently documented. This is a drawback since pathologies of the LHBT are a major source of shoulder pain.
Blumer, Roland +7 more
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Projection neurons in lamina III of the rat spinal cord are selectively innervated by local dynorphin-containing excitatory neurons [PDF]
, 2012 Large projection neurons in lamina III of the rat spinal cord that express the neurokinin 1 receptor are densely innervated by peptidergic primary afferent nociceptors and more sparsely by low-threshold myelinated afferents. However, we know little about
Baseer, N. +5 more
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