Results 1 to 10 of about 33,931 (282)
Calcitonin Gene-Related Peptide Monoclonal Antibody Utilization and Treatment Gaps in People with Migraine in Japan: Results from the OVERCOME (Japan) 2nd Study [PDF]
Drugs - Real World OutcomesBackground Calcitonin gene-related peptide monoclonal antibodies (CGRP mAbs) are an effective preventive treatment for migraine. However, their population-level utilization patterns and treatment gaps are underreported in Japan.
Yoshiki Hanaoka +9 more
doaj +2 more sources
Anti-CGRP antibodies block CGRP-induced diarrhea in mice [PDF]
Neuropeptides, 2017 The multifunctional neuropeptide calcitonin gene-related peptide (CGRP) and its receptor are expressed throughout the gastrointestinal tract. Previous studies have shown that CGRP has roles in intestinal motility, water secretion, and inflammation. Furthermore, animal studies have demonstrated CGRP involvement in diarrhea secondary to C.
Eric Kaiser +2 more
exaly +3 more sources
Vestibular Migraine: A Systematic Literature Search and Narrative Review of Diagnostic Criteria, Pathophysiology, Differential Diagnosis, and Treatment Approaches [PDF]
Medeniyet Medical JournalThis review aimed to summarize current evidence on the diagnostic criteria, pathophysiological mechanisms, differential diagnosis, and treatment approaches of vestibular migraine.
Ülkü Figen DEMIR +1 more
doaj +2 more sources
Клинический разбор в общей медицине, 2023 Background. Menstrual related migraine (MRM) occurs in 60% of women with migraine. These attacks are characterized by high intensity and poor response to abortive and prophylactic treatment.
Anna V. Berdnikova +4 more
doaj +1 more source
Journal of Neurology, 2016 Migraine has been estimated to be the seventh highest cause of disability worldwide, and the third most common disease worldwide after dental caries and tension type headache. However, the use of currently available acute and prophylactic medications to control this condition, such as 5-HT1 agonists (triptans) and beta-blockers, is limited by side ...
Cauchi, M., Robertson, Neil
openaire +2 more sources
The Journal of Headache and Pain, 2009 Dear Editor,Concentrations of substances in plasma, in this case CGRP,can be presented in several different to ways, such as pmol/l[1–7], pg/ml [8, 9] and just recently as ng/ml [10]. Thesedifferent concentrations can be compared when one usesthe molecular weight of 3,790 for CGRP but it takes 5–10 min of arithmetic to do that.
Tfelt-Hansen, Peer, Ashina, Messoud
openaire +3 more sources
Advances in CGRP monoclonal antibodies as migraine therapy: A narrative review
Saudi Journal of Medicine and Medical Sciences, 2023 Migraine is a potentially disabling disorder, yet it remains underdiagnosed and undertreated. The release of the neuropeptide calcitonin gene-related peptide (CGRP) in the trigemino-cerebrovascular system plays a vital role in the evolution of migraine ...
Suruchi Aditya, Aditya Rattan
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New strategies for migraine treatment and prevention
Aktualności Neurologiczne, 2019 Migraine is a neurological disorder characterised by recurrent attacks of headache accompanied by vegetative symptoms. It is estimated that 11–12% of the world’s population suffers from migraine.
Waldemar Brola, Piotr Sobolewski
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Serum calcitonin gene related peptide (CGRP) levels in migraine: A study on its clinical correlation and diagnostic efficacy [PDF]
Romanian Journal of Neurology, 2021 Migraine is a primary headache disorder marked by recurrent unilateral headache episodes. Calcitonin gene related peptide (CGRP) plays major role in migraine pathophysiology.
Sofia Khatoon +7 more
doaj +1 more source
The Management of High-Frequency Episodic and Chronic Migraines with Calcitonin Gene-Related Peptide Monoclonal Antibody [PDF]
Анналы клинической и экспериментальной неврологии, 2023 Introduction. High prevalence of migraine and its impact on quality of life requires the development of original agents. In 2020, fremanezumab, a new calcitonin gene-related peptide monoclonal antibody was authorized in Russia.
Larisa A. Dobrynina +4 more
doaj +1 more source