Results 11 to 20 of about 45,236 (268)
Parabrachial calcitonin gene-related peptide neurons sex-specifically modulate behavior in anxiety assays during alcohol withdrawal [PDF]
Parabrachial nucleus (PBN) neurons expressing Calcitonin Gene-Related Peptide (CGRP) modulate fear- and anxiety-like behavior. It is unknown if PBN(CGRP) neurons play a role in anxiety during withdrawal from alcohol or after repeated stress.
C. E. Van Doorn +9 more
doaj +2 more sources
Migraine has been estimated to be the seventh highest cause of disability worldwide, and the third most common disease worldwide after dental caries and tension type headache. However, the use of currently available acute and prophylactic medications to control this condition, such as 5-HT1 agonists (triptans) and beta-blockers, is limited by side ...
Cauchi, M., Robertson, Neil
openaire +2 more sources
Dear Editor,Concentrations of substances in plasma, in this case CGRP,can be presented in several different to ways, such as pmol/l[1–7], pg/ml [8, 9] and just recently as ng/ml [10]. Thesedifferent concentrations can be compared when one usesthe molecular weight of 3,790 for CGRP but it takes 5–10 min of arithmetic to do that.
Tfelt-Hansen, Peer, Ashina, Messoud
openaire +3 more sources
Anti-CGRP antibodies block CGRP-induced diarrhea in mice [PDF]
The multifunctional neuropeptide calcitonin gene-related peptide (CGRP) and its receptor are expressed throughout the gastrointestinal tract. Previous studies have shown that CGRP has roles in intestinal motility, water secretion, and inflammation. Furthermore, animal studies have demonstrated CGRP involvement in diarrhea secondary to C.
Eric A, Kaiser +6 more
openaire +2 more sources
It is known that calcitonin gene-related peptide (CGRP) plays a key role in pain modulation in the brain. There are high expressions of CGRP and CGRP receptor in anterior cingulate cortex (ACC), an important brain structure in pain modulation.
Ke-Sai Hou +5 more
doaj +1 more source
Axons Giving Rise to the Palisade Endings of Feline Extraocular Muscles Display Motor Features [PDF]
Palisade endings are nerve specializations found in the extraocular muscles (EOMs) of mammals, including primates. They have long been postulated to be proprioceptors. It was recently demonstrated that palisade endings are cholinergic and that in monkeys
Davis López de Carrizosa, María América +5 more
core +1 more source
Oralee J Varnado,1 Janna Manjelievskaia,2 Wenyu Ye,1 Allison Perry,2 Kory Schuh,1 Richard Wenzel1 1Value, Evidence, and Outcomes, Eli Lilly and Company, Indianapolis, IN, USA; 2Watson Health Life Sciences, Research & Analytics, IBM Watson Health ...
Varnado OJ +5 more
doaj
Background The clinical use of calcitonin gene-related peptide receptor (CGRP-R) antagonists and monoclonal antibodies against CGRP and CGRP-R has offered new treatment possibilities for migraine patients.
Sanne Hage La Cour +6 more
doaj +1 more source
Flavia Lo Castro,1 Simona Guerzoni,1 Lanfranco Pellesi2 1Medical Toxicology, Headache and Drug Abuse Research Center, Department of Specialized Medicine, AOU Policlinico di Modena, Modena, Italy; 2Danish Headache Center, Department of Neurology ...
Lo Castro F, Guerzoni S, Pellesi L
doaj
Introduction. Migraine is one of the most common disabling neurological disorders. Recently developed monoclonal antibodies to calcitonin gene-related peptide (CGRP) or its receptor are the first targeted medication for preventive therapy of both ...
N. V. Vashchenko +5 more
doaj +1 more source

