Results 31 to 40 of about 33,931 (282)

CGRP and migraine from a cardiovascular point of view: what do we expect from blocking CGRP? [PDF]

, 2019
Calcitonin gene-related peptide (CGRP) is a neuropeptide with a pivotal role in the pathophysiology of migraine. Blockade of CGRP is a new therapeutic target for patients with migraine. CGRP and its receptors are distributed not only in the central and
Paolo Martelletti, Verzina, A., Guglielmetti, M., Koniari, C., Martelletti, P., Marge Vaikjärv, Mavridis, T., Bart Zick, Al-Hassany, Linda, Sacco, S, Chrysoula Koniari, Giani, L., Verhagen, I., Butera, C., Theodoros Mavridis, den Boer, I., Zick, B., Luca Giani, Giani, L, Verzina, A, Iris Verhagen, Linda Al-Hassany, Vaikjarv, M, Martelletti, P, Valentina Favoni, Simona Sacco, Favoni, V, Guglielmetti, M, Zick, Bart, Verhagen, Iris, Favoni, V., Koniari, C, Al-Hassany, L., Butera, C, Al-Hassany, Linda; id_orcid, Boer, I, Angela Verzina, Asioli, GM, Mavridis, T, Asioli, G.M., Gian Maria Asioli, Sacco, S., Martina Guglielmetti, Vaikjarv, M., Irene de Boer, European Headache Federation School of Advanced Studies (EHF-SAS), Calogera Butera   +46 more
core   +5 more sources

Comparison of Early-onset Efficacy of Anti-calcitonin Gene-related Peptide Monoclonal Antibodies for Patients with Migraine in Real-world Clinical Practice: Study Protocol for an Exploratory Clinical Trial

Neurologia Medico-Chirurgica
Three anti-calcitonin gene-related peptide monoclonal antibodies (CGRP-mAbs) are available in Japan: galcanezumab, fremanezumab, and erenumab. Early-onset efficacy has been demonstrated for each CGRP-mAb in comparison with placebo, but differences among ...
Takafumi TANEI, Satoshi MAESAWA, Yusuke NISHIMURA, Tomotaka ISHIZAKI, Yoshitaka NAGASHIMA, Miki HASHIDA, Shun YAMAMOTO, Masahiko ANDO, Yachiyo KUWATSUKA, Atsushi HASHIZUME, Toshihiko WAKABAYASHI, Ryuta SAITO   +11 more
doaj   +1 more source

Safety and Risk of Medication Overuse Headache in Lasmiditan and Second-Generation Gepants: A Rapid Review

Drug, Healthcare and Patient Safety, 2021
Flavia Lo Castro,1 Simona Guerzoni,1 Lanfranco Pellesi2 1Medical Toxicology, Headache and Drug Abuse Research Center, Department of Specialized Medicine, AOU Policlinico di Modena, Modena, Italy; 2Danish Headache Center, Department of Neurology ...
Lo Castro F, Guerzoni S, Pellesi L
doaj  

The PLGA nanoparticles for sustainable release of CGRP to ameliorate the inflammatory and vascular disorders in the lung of CGRP-deficient rats

Drug Delivery, 2021
The calcitonin gene-related peptide (CGRP) has been demonstrated relating to vascular and inflammatory regulations not only the nerve systems. As the anti-inflammation factor and the most potent vasodilator, the CGRP holds therapeutic potentials for the ...
Fang Wang, Yu Deng, Jieting Wang, Luying Yu, Fadian Ding, Wei Lian, Qicai Liu, Xinhua Lin   +7 more
doaj   +1 more source

CGRP in rat mesenteric artery and vein - receptor expression, CGRP presence and potential roles

, 2020
CGRP is a potent dilator of arteries and despite rich perivascular CGRP immunoreactivity in both arteries and veins the role of CGRP in veins remains unknown.
Grell, Anne Sofie,, Edvinsson, Lars,, Warfvinge, Karin,, Sams, Anette,, Le, Thi Lisa,, Sheykhzade, Majid,, Lund University.   +6 more
core   +2 more sources

Nociceptor Neurons are Involved in the Host Response to Escherichia coli Urinary Tract Infections

Journal of Inflammation Research, 2022
Zhengdong Gao,1,2,* Yaxiao Liu,1,2,* Lekai Zhang,1,2 Zizhuo Yang,1,2 Linchen Lv,1,2 Shuai Wang,1,2 Lipeng Chen,1,2 Nan Zhou,1,2 Yaofeng Zhu,1 Xuewen Jiang,1 Benkang Shi,1,2 Yan Li1,2 1Department of Urology, Qilu Hospital of Shandong University ...
Gao Z, Liu Y, Zhang L, Yang Z, Lv L, Wang S, Chen L, Zhou N, Zhu Y, Jiang X, Shi B, Li Y   +11 more
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The Anti-CGRP Antibody Fremanezumab Lowers CGRP Release from Rat Dura Mater and Meningeal Blood Flow [PDF]

, 2022
Monoclonal antibodies directed against the neuropeptide calcitonin gene-related peptide (CGRP) belong to a new generation of therapeutics that are effective in the prevention of migraine.
Messlinger, Karl, Dux, Mária, Birgit Vogler, Kuhn, Annette, Annette Kuhn, Vogler, Birgit, Mackenzie, Kimberly D., Karl Messlinger, Mária Dux, Kimberly D. Mackenzie, Stratton, Jennifer, Jennifer Stratton   +11 more
core   +1 more source

On Tribo-Test Machine Integrating Pin-on-Disc and Block-on-Ring

Tribology Online, 2007
A concept of integrating more than one tribo-technique, Pin-on-Disc (POD) and Block-on-Ring (BOR), working simultaneously under same test conditions against same counterface is introduced in a new multi-tribo-test-machine. In this machine, different wear
Belal F. Yousif, Nabil. S. M. El-Tayeb
doaj   +1 more source

An Investigation into the Prevalence of Migraine and Its Prophylactic Treatment Patterns in the Czech Republic: An Observational Study

Journal of Pain Research, 2020
David Dolezil,1 Jolana Markova,2 Jiri Klimes,3,4 Zuzana Pocikova,3,4 Filip Dostal,3,4 Radka Stepanova,5,6 Adam Svobodnik5,7 1Prague Headache Center, DADO MEDICAL s.r.o., Prague, Czech Republic; 2University Thomayer Hospital, Prague, Czech Republic ...
Dolezil D, Markova J, Klimes J, Pocikova Z, Dostal F, Stepanova R, Svobodnik A   +6 more
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Review of Tolerability of Fremanezumab for Episodic and Chronic Migraine

Neuropsychiatric Disease and Treatment, 2023
Shane Root,1– 3 Kevin Ahn,3 Jack Kirsch,3 Justin L Hoskin1– 3 1Department of Neurology, Barrow Neurological Institute, Phoenix, AZ, USA; 2University of Arizona School of Medicine, Phoenix, AZ, USA; 3Creighton University School of Medicine, Omaha, NE ...
Root S, Ahn K, Kirsch J, Hoskin JL
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