Results 1 to 10 of about 188,451 (293)

Alternative TEL-JAK2 fusions associated with T-cell acute lymphoblastic leukemia and atypical chronic myelogenous leukemia dissected in zebrafish [PDF]

Haematologica, 2012
Background Chromosomal translocations resulting in alternative fusions of the human TEL (ETV6) and JAK2 genes have been observed in cases of acute lymphoblastic leukemia and chronic myelogenous leukemia, but a full understanding of their role in disease ...
Sara M. N. Onnebo, Parisa Rasighaemi, Janani Kumar, Clifford Liongue, Alister C. Ward   +4 more
doaj   +6 more sources

Has the time for first-line treatment with second generation tyrosine kinase inhibitors in patients with chronic myelogenous leukemia already come? Systematic review and meta-analysis

Haematologica, 2013
Second generation tyrosine kinase inhibitors have recently been introduced as first-line treatment for chronic phase chronic myelogenous leukemia. We aimed to evaluate the efficacy and safety of 2nd generation tyrosine kinase inhibitors versus imatinib ...
Ronit Gurion, Anat Gafter-Gvili, Liat Vidal, Avi Leader, Ron Ram, Adi Shacham-Abulafia, Mical Paul, Isaac Ben-Bassat, Ofer Shpilberg, Pia Raanani   +9 more
doaj   +4 more sources

A case of chronic myelogenous leukemia in pregnancy characterized by a complex translocation t(9;22;11)(q34;q11.2;q13) [PDF]

Hematology Reports, 2011
The management of chronic myelogenous leukemia during pregnancy requires balancing the well-being of the mother with that of the fetus. We report a case of a 26-year-old lady who was diagnosed with chronic myelogenous leukemia (CML) at 15 weeks gestation
Surachit Kumar, Mariya Apostolova, Paul V. Woolley   +2 more
doaj   +2 more sources

A label free chemoproteomic-based platform to disclose cannabidiol molecular mechanism of action on chronic myelogenous leukemia cancer cells [PDF]

Heliyon
The discovery of the interactome of cannabidiol (CBD), a non-psychoactive cannabinoid from Cannabis sativa L., has been here performed on chronic myelogenous leukemia cancer cells, using an optimized chemo-proteomic stage, which links Drug Affinity ...
Sara Ceccacci, Lorenzo Corsi, Lucio Spinelli, Clarissa Caroli, Matilde Marani, Lisa Anceschi, Matteo Mozzicafreddo, Federica Pellati, Maria Chiara Monti   +8 more
doaj   +2 more sources

Successful treatment of myeloid blast phase chronic myelogenous leukemia with the JAK2 V617 F mutation by combination therapy with asciminib and ropeginterferon alfa-2b in an elderly patient. [PDF]

Int J Hematol
Oka S, Akagi Y, Mituyoshi T, Ono K.
europepmc   +3 more sources

Chronic myelogenous leukemia coexpressing V-e16a2, V-e13a2, e13a2, and e14a2 BCR::ABL1 fusion transcripts: a case report and review of the literature. [PDF]

Front Oncol
Xu Y, Fan Y, Liu S, Chang J, Guo C, Chen L, Guo W, Dang J, Wang H, Tan Y.   +9 more
europepmc   +3 more sources

Chronic Myelogenous Leukemia [PDF]

Journal of the National Comprehensive Cancer Network, 2012
Chronic myelogenous leukemia (CML) is the one of the most common chronic myeloproliferative disorders. It has become the paradigmatic disease for molecular diagnosis and monitoring for several reasons: (1) CML has a unitary molecular definition, requiring the demonstration of the t(9;22)(q34;q11) chromosomal translocation or its product, the BCR-ABL ...
Susan, O'Brien, Camille N, Abboud, Mojtaba, Akhtari, Jessica, Altman, Ellin, Berman, Daniel J, DeAngelo, Steven, Devine, Amir T, Fathi, Jason, Gotlib, Madan, Jagasia, Joseph O, Moore, Javier, Pinilla-Ibarz, Jerald P, Radich, Vishnu V B, Reddy, Neil P, Shah, Paul J, Shami, B Douglas, Smith, David S, Snyder, Meir, Wetzler, Furhan, Yunus   +19 more
openaire   +4 more sources

Granulocytic Sarcoma with Compressive Myelopathy: A Rare Presentation of Chronic Myelogenous Leukemia [PDF]

Journal of Clinical and Diagnostic Research, 2014
Granulocytic sarcoma occurs most commonly in acute myelogenous leukemia. The appearance of granulocytic sarcoma in chronic myelogenous leukemia signals accelerated phase/ blast transformation.
Abhijeet P. Ganapule, Auro Viswabandya, Anita Jasper, Palak Patel, Gautami Kokil   +4 more
doaj   +1 more source

Chronic Myelogenous Leukemia [PDF]

Hematology, 2002
Abstract The treatment options for chronic myelogenous leukemia (CML) continue to evolve rapidly. Imatinib mesylate (Gleevec, Glivec, formerly STI571) has continued to show remarkable clinical benefits and the updated results with this agent are reviewed.
Brian J, Druker, Stephen G, O'Brien, Jorge, Cortes, Jerald, Radich   +3 more
openaire   +3 more sources

Pharmacoeconomic modeling of target therapy of chronic myeloid leukemia in remission

Онкогематология, 2015
The article presents example of modeling for pharmacoeconomical-founded choice of chronic myelogenous leukemia treatment strategy related to therapeutic efficacy and economical rationality. The economic model of chronic myelogenous leukemia diagnosis and
V. A. Shuvaev, K. M. Abdulkadyrov, I. S. Martynkevich, M. S. Fominykh   +3 more
doaj   +3 more sources