Results 141 to 150 of about 41,447 (182)
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Priapism in chronic myelogenous leukemia
The Indian Journal of Pediatrics, 1992Twelve year old boy, was admitted at the All India Institute of Medical Sciences, New Delhi in March 1990 with a history of left hypochondrial mass for six years and priapism for 2 days. He had an episode of priapi.~m one month ago, which spontaneously subsided within 8 hours Examination revealed mild pallor, sternal tenderness and gcneralized ...
P, Bhatia +4 more
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Juvenile Chronic Myelogenous Leukemia
Journal of Pediatric Hematology/Oncology, 1988Juvenile chronic myelogenous leukemia (JCML) is a malignant hematopoietic disorder of monocyte-histiocyte lineage that affects children less than 4 years of age. Since the disease represents only 2% of all childhood leukemias, experience with it has been limited even in large centers.
M H, Freedman, Z, Estrov, H S, Chan
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Immunity to chronic myelogenous leukemia
Hematology/Oncology Clinics of North America, 2004Given the high rate of cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia (CML), logical future treatment strategies will include combinations of tyrosine kinase inhibitors and immunotherapies such as vaccines. Increased understanding of highly specific immune responses will lead to novel and improved immunotherapy strategies ...
Dax, Kurbegov, Jeffrey J, Molldrem
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Treatment of chronic myelogenous leukemia
American Journal of Health-System Pharmacy, 2016Treatment options for chronic-phase chronic myelogenous leukemia (CML) based on medication-resistant mutations in BCR-ABL are reviewed.Imatinib, nilotinib, and dasatinib are first-line therapies for chronic-phase CML. Nilotinib or dasatinib can be used as first- or second-line treatment, with nilotinib preferred in patients with BCR-ABL F317 and V229 ...
Christine, Kujak, Jill M, Kolesar
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Chronic Myelogenous Leukemia in Infancy
Mayo Clinic Proceedings, 1944Chronic myelogenous leukemia is uncommon in childhood and rare in infancy. The disease seldom occurs in infants less than 6 months of age. In 1933, Cooke1reported 3 cases encountered in the St. Louis Children's Hospital during a period of fifteen years. The patients were 8 years old or older.
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Therapy of chronic myelogenous leukemia
Cancer, 1987While the demonstrated antiviral, antiproliferative, and immunomodulatory properties of interferons have led to a number of theories regarding their potential use in treating individuals with chronic myelogenous leukemia (CML), their limited availability has prevented thorough clinical investigation.
M, Talpaz +5 more
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Chronic myelogenous leukemia in children
The Journal of Pediatrics, 1953Summary Observations were reported on fifteenchildren with chronic myelogenous leukemia. During infancy the clinical manifestations were chiefly of a hemorrhagic character and associated with thrombocytopenia. In older children the disease was essentially the same as seen in adults. The best results in therapy were obtained by x-ray irradiation given
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Chronic myelogenous leukemia in chronic phase
Current Treatment Options in Oncology, 2001Chronic myelogenous leukemia (CML) is a clonal myeloproliferative disorder characterized by genomic instability leading to its inevitable clinical evolution from an easily controlled chronic phase to a terminal blastic phase. The molecular abnormality responsible for this disease--BCR-ABL--and the critical biochemical aberrations resulting from it have
R, Kurzrock, H, Kantarjian, M, Talpaz
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Coexistence of chronic myelogenous leukemia and chronic lymphocytic leukemia
Cancer, 1984A 55-year-old man is reported who initially developed chronic lymphocytic leukemia. Seven years later, after chemotherapy with chlorambucil, chronic myelogenous leukemia was diagnosed in addition to the chronic lymphocytic leukemia. Four previously reported cases with the same sequence of events are reviewed as well as cases of chronic myelogenous ...
Z A, Schreiber, M R, Axelrod, L S, Abebe
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Southern Medical Journal, 1980
A 25-year-old woman presented with classic features of chronic myelogenous leukemia. After 15 months of control with splenic irradiation, rising blood counts necessitated busulfan therapy, producing severe thrombocytopenia which persisted for nearly three years.
R S, Stein, J M, Flexner
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A 25-year-old woman presented with classic features of chronic myelogenous leukemia. After 15 months of control with splenic irradiation, rising blood counts necessitated busulfan therapy, producing severe thrombocytopenia which persisted for nearly three years.
R S, Stein, J M, Flexner
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