Results 51 to 60 of about 41,447 (182)
ABSTRACT Objective To investigate the development of oral premalignant and malignant lesions as a major long‐term complication following hematopoietic stem cell transplantation. Methods This single‐center retrospective study identified 17 patients who developed 26 pathology‐confirmed oral premalignant and malignant lesions after hematopoietic stem cell
Pei Hsuan Lu +3 more
wiley +1 more source
Chronic myelogenous leukemia occurring in a chronic lymphocytic leukemia patient
Key Clinical Message Occurrence of two different hematological malignancies is very infrequent, and it is nevertheless important not to neglect basic examinations in patients follow‐up.
Jenny Beaud +3 more
doaj +1 more source
Background In this report, the isorhamnetin 3-o-robinobioside and its original extract, the ethyl acetate extract, from Nitraria retusa leaves, were evaluated for their ability to induce antioxidant and antigenotoxic effects in human chronic myelogenous ...
Boubaker Jihed +4 more
doaj +1 more source
Vacuolization as a Novel Approach to Cancer Therapy
This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak +9 more
wiley +1 more source
A semi‐automated approach for early prenatal diagnosis is developed for low‐cellularity samples from coelocentesis by exploiting biotin/streptavidin interaction to functionalize electrospun mats with antibodies. With potential microfluidic integration, the resulting platform enables fetal cell capture, offering a strategy toward improved efficiency and
Emanuela Muscolino +3 more
wiley +1 more source
HLA Class II Allele and Haplotype Frequencies in Iranian Patients with Leukemia
Previous studies demonstrated significant differences in a number of HLA allele frequencies in leukemia patients and normal subjects. In this study, we have analyzed HLA class II alleles and haplotypes in 110 leukemia patients (60 acute myelogenous ...
Farideh Khosravi +7 more
doaj
The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao +4 more
wiley +1 more source
Third‐Generation Nanopore Sequencing for Post‐Transplant Chimerism Monitoring
ABSTRACT Post‐transplant chimerism monitoring is a cornerstone of hematopoietic stem cell transplantation (HSCT) follow‐up, providing early and clinically actionable information on engraftment, graft rejection and disease relapse. Analytical strategies have progressively evolved from STR‐based assays towards more sensitive molecular approaches ...
Pascal Pedini +7 more
wiley +1 more source
The role of Lyn kinase in the development of imatinib resistance in chronic myelogenous leukemia
Imatinib mesylate, a small-molecule inhibitor of BCRABL tyrosine kinase activity, has emerged as the well-recognized standard of treatment for chronic myelogenous leukemia (CML). Indeed, both its efficacy, tolerability, as well as cost-effectiveness have
Camillo Porta, Federica Tagliani
doaj +1 more source
The authors report a case with pericardial effusion and cardiac tamponade as a rare clinical manifestation of chronic graft-versus-host disease in a young man with acute myelogenous leukemia submitted to an allogeneic hematopoietic stem cell ...
David Cavalcanti Ferreira +3 more
doaj +1 more source

