Results 71 to 80 of about 188,451 (293)

AS1041, a Novel Synthesized Derivative of Marine Natural Compound Aspergiolide A, Arrests Cell Cycle, Induces Apoptosis, and Inhibits ERK Activation in K562 Cells

open access: yesMarine Drugs, 2017
AS1041 is a novel synthesized anthraquinone lactone derivative of marine natural compound aspergiolide A (ASP-A) with new structure skeleton and marked cytotoxicity in cancer cells.
Fengli Yuan   +8 more
doaj   +1 more source

Chronic myeloid leukemia-clinical, experimental and health economic studies with special reference to imatinib treatment [PDF]

open access: yes, 2013
CML is a malignant disease that originates in the bone marrow stem cell, carrying the Philadelphia chromosome with the BCR-ABL fusion gene. This gene translates into an active tyrosine kinase, Bcr-Abl, affecting hematopoiesis, particularly resulting in ...
Ohm, Lotta
core   +1 more source

Trends in US Hematology/Oncology Physician Perceptions and Referral Practices for Hematopoietic Cell Transplant: A National Survey Conducted by NMDP

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background To evaluate trends in allogeneic hematopoietic cell transplant (HCT) referral perceptions and practices, we compared surveys of Hematology‐Oncology (Hem‐Onc) physicians conducted in 2015 (N = 150), 2019 (N = 302), and 2024 (N = 183) and reported changes over time.
Aye Mon Thida   +7 more
wiley   +1 more source

Chloroma of the Testis After Allogeneic Peripheral Blood Stem Cell Transplantation: A Case Report

open access: yesKaohsiung Journal of Medical Sciences, 2004
Chloroma, or granulocytic sarcoma, is a rare extramedullary solid hematologic cancer that affects many sites, usually in concert with acute myeloid leukemia.
Shih-Wen Hu   +2 more
doaj   +1 more source

Chronic Myelogenous Leukemia [PDF]

open access: yesLaboratory Medicine, 2000
Chronic myelogenous leukemia (CML) is the most common and best studied of the chronic myeloproliferative disorders, resulting from a characteristic Philadelphia chromosomal abnormality, t(9;22)(q34q11). The molecular consequence of this chromosomal translocation is production of a hybrid BCR-ABL (breakpoint cluster region–Abelson leukemia virus) fusion
Karl Gaal, Daniel A. Arber
openaire   +1 more source

Comparison of total body irradiation-based or non-total body irradiation-based conditioning regimens for allogeneic stem cell transplantation in pediatric leukemia patients [PDF]

open access: yes, 2010
Purpose : This study aims to compare the outcome of total body irradiation (TBI)- or non-TBI-containing conditioning regimens for leukemia in children. Methods : We retrospectively evaluated 77 children conditioned with TBI (n=40) or non-TBI (n= ...
Dong Kyun Han   +6 more
core   +1 more source

Total Synthesis of the Cyanobacterial Alkaloid Nostodione A

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 2, January 16, 2026.
The total synthesis of the alkaloid nostodione A is successfully achieved utilizing 3,4‐dihydrocyclopenta[b]indole‐1,2‐dione as a key intermediate. The sensitive benzylidene moiety is introduced via a Knoevenagel condensation with p‐hydroxybenzaldehyde.
Oscar F. Casadiego‐Díaz   +3 more
wiley   +1 more source

Chronic myelogenous leukemia on target

open access: yesCancer Medicine, 2018
Chronic myelogenous leukemia (CML) is commonly treated with tyrosine kinase inhibitors (TKIs) that inhibit the pro‐leukemic activity of the BCR‐ABL1 oncoprotein.
Veronika Némethová, Filip Rázga
doaj   +1 more source

Induction of Apoptosis, G0/G1 Phase Arrest and Microtubule Disassembly in K562 Leukemia Cells by Mere15, a Novel Polypeptide from Meretrix meretrix Linnaeus

open access: yesMarine Drugs, 2012
Mere15 is a novel polypeptide from Meretrix meretrix Linnaeus with cytotoxicity in solid cancer cells. In this study, we investigated its activity on human K562 chronic myelogenous leukemia cells.
Xiukun Lin   +8 more
doaj   +1 more source

Chronic Myelogenus Leukemia: approaches to pharmacological resistance [PDF]

open access: yes, 2017
Chronic myelogenous leukemia (CML) is a clonal myeloproliferative disorder characterized by the reciprocal t (9:22) chromosomal translocation. This rearrangement produces the socalled Philadelphia chromosome carrying the chimeric Bcr-Abl oncoprotein ...
Corrado, C.
core   +1 more source

Home - About - Disclaimer - Privacy