Results 91 to 100 of about 125,713 (396)

Chronic Myeloid Leukaemia in Advanced Phase: An Analytical Evaluation

open access: yesJournal of Rawalpindi Medical College, 2019
Objective: To evaluate the clinical and morphological features in advanced phase chronic myeloid leukaemia. Methods: This descriptive observational study was conducted at the Pathology Unit of Fauji Foundation Hospital, Rawalpindi from June 2012 till ...
Sehar Khaliq
doaj  

A Novel C19orf47‐AKT2 Chimeric RNA Generated by Cis‐Splicing of Adjacent Genes Is Associated With Glioblastoma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Malignant gliomas pose significant therapeutic challenges. This study aimed to identify and characterize a novel chimeric RNA in glioma and assess its clinical and functional significance for precision treatment. Methods The C19orf47‐AKT2 chimeric RNAs were identified through RNA sequencing and validated by polymerase chain reaction.
Zihan Wang   +11 more
wiley   +1 more source

Haematological malignancy: are we measuring what is important to patients? A systematic review of quality of life instruments [PDF]

open access: yes, 2019
© 2018 The Authors. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for
Goswami, Pushpendra   +2 more
core   +2 more sources

The underestimated role of basophils in Ph+ chronic myeloid leukaemia

open access: yesEuropean Journal of Clinical Investigation, 2018
Chronic myeloid leukaemia (CML) is a hematopoietic neoplasm defined by the chromosome translocation t(9;22) and the related oncogene, BCR‐ABL1. In most patients, leukaemic cells can be kept under control using BCR‐ABL1‐targeting drugs.
P. Valent, H. Horny, M. Arock
semanticscholar   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

open access: yesAdvanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang   +5 more
wiley   +1 more source

Biomarkers of leukemia risk: benzene as a model. [PDF]

open access: yes, 1998
Although relatively rare, leukemias place a considerable financial burden on society and cause psychologic trauma to many families. Leukemia is the most common cancer in children.
Smith, MT, Zhang, L
core   +3 more sources

Chronic myeloid leukaemia: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

open access: yesAnnals of Oncology, 2017
Klinik für Innere Medizin II, H€amatologie/Onkologie, Universit€atsklinikum Jena, Jena; III. Medizinische Klinik, Universit€atsmedizin Mannheim, Fakult€at für Klinische Medizin Mannheim der Universit€at Heidelberg, Mannheim, Germany; Department of ...
A. Hochhaus   +7 more
semanticscholar   +1 more source

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

open access: yesAdvanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali   +5 more
wiley   +1 more source

Systemic mastocytosis with associated myeloproliferative disease and precursor B lymphoblastic leukaemia with t(13;13)(q12;q22) involving FLT3. [PDF]

open access: yes, 2008
Systemic mastocytoses represent neoplastic proliferations of mast cells. In about 20% of cases systemic mastocytoses are accompanied by clonal haematopoietic non-mast cell-lineage disorders, most commonly myeloid neoplasms.
Dirnhofer, S.   +7 more
core   +1 more source

Acute disseminated intravascular coagulation following surgical resection of a myeloid sarcoma in a 57-year-old male

open access: yesClinics and Practice, 2012
Myeloid sarcoma is a rare extramedullary tumour consisting of immature myeloid cells. It can arise at any anatomical location and often develops in the bowel.
Rohan Paul   +3 more
doaj   +1 more source

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