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Stem cells in chronic myeloid leukaemia [PDF]
Over the last decade, the stem cell field has been one of the most fascinating areas of medical research. In several types of malignancy, both haematological and solid tumours, tissue stem cells are now implicated as cancer initiating cells. Chronic myeloid leukaemia (CML) is a paradigm cancer in this field.
Tessa L. Holyoake, Francesca Pellicano
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Mechanisms of Resistance and Implications for Treatment Strategies in Chronic Myeloid Leukaemia
Simple Summary Chronic myeloid leukaemia (CML) is a type of blood cancer that is currently well-managed with drugs that target cancer-causing proteins. However, a significant proportion of CML patients do not respond to those drug treatments or relapse ...
Govinda Poudel+3 more
semanticscholar +1 more source
Chronic myeloid leukaemia presenting as acute small bowel gangrene: A case report
Rationale: Chronic myeloid leukaemia is a myeloproliferative disorder due to clonal hyperproliferation of myeloid cells within the bone marrow. It can present both pro- and anti-thrombotic states.
Jayabal Pandiaraja, Arumugam Shalini
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Treatment of blast phase chronic myeloid leukaemia: A rare and challenging entity
Despite the success of BCR‐ABL‐specific tyrosine kinase inhibitors (TKIs) such as imatinib in chronic phase (CP) chronic myeloid leukaemia (CML), patients with blast phase (BP)‐CML continue to have a dismal outcome with median survival of less than one ...
M. Copland
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Spinal Chloroma – Herald of blast crisis in a patient with chronic myeloid leukaemia: A case report
Myeloid sarcoma or chloroma is a localised tumour characterised by extramedullary proliferation of precursor myeloid cells. Commonly occurring in association with acute myeloid leukaemia, chloroma can occasionally be seen in myeloproliferative disorders ...
Stuti Chandola+3 more
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Leukaemic Ascites and Peritoneal Myeloid Sarcoma: Rare but Not Impossible
A myeloid sarcoma is an extramedullary tumour arising from infiltration by leukemic cells at an anatomic site other than the bone marrow. Most commonly it precedes acute myeloid leukaemia but occasionally occurs simultaneously.
Luís Landeiro+4 more
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Background Chronic myeloid leukaemia is characterised by genetic instability which results in additional cytogenetic aberrations that have been linked to progression to advanced phase.
Hend Attia, Dina Adel Fouad, Heba Samy
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Classification of Acute Leukaemia based on Blast Morphology, Cytochemistry and Flow Cytometry [PDF]
Introduction: Acute leukaemias are a heterogeneous group of malignancies due to the abnormal proliferation of immature cells. The classification of acute leukaemia has been transformed over a period.
P Jubit Paulose, J Latha Fathima
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Chronic myeloid leukaemia in India [PDF]
Pankaj Malhotra, Subhash Varma
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Leukaemia Cutis: Clinical Features and Outcomes of 56 Patients
Leukaemia is a malignant neoplasm of the haematopoietic system. Cutaneous manifestations of leukaemia are called leukaemia cutis, and are regarded as a sign of poorer prognosis and shorter survival time.
Hwa Jung Yook+8 more
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