Results 241 to 250 of about 71,029 (345)

Engineering Dosimetric Excellence In Total Body Irradiation: Tomotherapy‐Driven Protocols for Precision and Reproducibility

Precision Radiation Oncology, EarlyView.
• Objective: Assess helical Tomotherapy‐based TBI for clinical feasibility, dosimetric reproducibility, and in‐vivo accuracy using dual‐orientation simulation and patient‐specific QA. • Methodology: Implementation of ArcCHECK 3D diode array, ionization chamber verification, and in‐vivo dosimetry with OSLDs at 16 anatomical sites to ensure precise dose ...
Sandeep Singh, Dipesh, Supratik Sen, Abhay Kumar Singh, Mahipal, Manindra Bhushan, Jaskaran Singh Sethi, David K. Simson, Munish Gairola   +8 more
wiley   +1 more source

Semi‐mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 448-459, March 2025.
Abstract Myelodysplastic syndromes (MDS) represent a group of bone marrow disorders involving cytopenias, hypercellular bone marrow, and dysplastic hematopoietic progenitors. MDS remains a challenge to treat due to the complex interplay between disease‐induced and treatment‐related cytopenias.
Neha Thakre, Corinna Maier, Jiuhong Zha, Benjamin Engelhardt, Johannes E. Wolff, Sven Mensing   +5 more
wiley   +1 more source

BCR::ABL1-positive chronic myeloid leukaemia in a scenario of a remote diagnosis of JAK2-V617F-mutated polycythemia vera: a single patient experience with imatinib and ruxolitinib combination therapy. [PDF]

Ann Hematol
Bartolucci P, Gigli F, Tabanelli V, Valeriano A, Gregato G, Poletti C, Bertolini F, Derenzini E.   +7 more
europepmc   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said, Job R. Schippers, Leila Atmowihardjo, Yingxue Li, Mick S. van der Plas, Harm J. Bogaard, Lieuwe D. J. Bos, Ron A. A. Mathôt, Jurjan Aman, Eleonora L. Swart, Imke H. Bartelink   +10 more
wiley   +1 more source

Therapeutic drug monitoring of imatinib in paediatric chronic myeloid leukaemia: Data from a real-world setting. [PDF]

Br J Haematol
Suttorp M, Sembill S, Lensker P, Hildebrand V, Schirmer E, Karow A, Krumbholz M, Rauh M, Metzler M.   +8 more
europepmc   +1 more source

Detection of residual host cells after bone marrow transplantation using non-isotopic in situ hybridization [PDF]

, 1993
Cremer, Thomas, Knuutila, Sakari, Popp, Susanne, Ruutu, Tapani, Volin, L., Wessman, M.   +5 more
core  

Hepatic Portal Venous Gas Secondary to Intestinal Obstruction Complicated by Chronic Myeloid Leukaemia: A Case Report

Shidong Wang, Xianbin Liu, Shilei Li, Shuai Liu, T Solakoglu, S Sari, H Koseoglu, M Basaran, M Akar, 1 Buyukasik, S, P S413 Liebman, M Patten, J Manny, J Benfield, H Hechtman, Y Tong, J Zheng, S Su, Y Qiao, M Han, C Wang, Jin Xue, H Zhang, Y, W Fangfei, L Shaocheng, C Di, R Zhangyong, L Lixin, Qiang, H Kinoshita, M Shinozaki, H Tanimura, Y Umemoto, 7 Sakaguchi, S Takifuji, K, K Suto, T Hikichi, Y Shioya, N Ishizaki, S Saito, J Nakamura, C Seak, C Ng, D Yen, Y Wong, K Hsu, J Seak, T Seike, T Suda, N Oishi   +52 more
openalex   +2 more sources

The JAK2 V617F Mutation in Chronic Myeloid Leukaemia within a BCR-ABL Positive Cohort of Beninese Patients

, 2018
Simon Azonbakin, Bienvenu Houssou, I. Azannai, B Awede, Romaric Massi, Marius Adjagba, A Agbalinsou, Ludovic Anani, Raphaël Darboux, Flore Gangbo, A Lalèyè   +10 more
openalex   +1 more source

Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment

Rare Metals, EarlyView.
ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang, Jiatong Lin, Yi Peng, Zehua Wu, Yingying Liu, Wei Duan, Qiaolin Wei, Jia‐Wei Shen, Jiang‐Xing Chen, Yong Guo   +9 more
wiley   +1 more source

Mismatched related donor allogeneic haematopoietic cell transplantation compared to other donor types for Ph+ chronic myeloid leukaemia: A retrospective analysis from the Chronic Malignancies Working Party of the EBMT [PDF]

Francesco Onida, Luuk Gras, Junran Ge, Linda Köster, Rose‐Marie Hamladji, Jenny Byrne, Daniele Avenoso, Mahmoud Aljurf, Marie Robin, Kazimierz Hałaburda, Jakob Passweg, Urpu Salmenniemi, Henrik Sengeloev, Jane F. Apperley, Andrew Clark, Péter Reményi, Elena Morozova, Francesca Kinsella, Stig Lenhoff, Arnold Ganser, Ka Lung Wu, Antonio Pérez‐Martínez, Patrick Hayden, Kavita Raj, Joanna Drozd‐Sokołowska, Guillermo Ortí, Hugues de Lavallade, Ibrahim Yakoub‐Agha, Donal P. McLornan, Yves Chalandon   +29 more
openalex   +1 more source