Results 251 to 260 of about 71,029 (345)

Progress in Surface‐Enhanced Raman Scattering‐Based Volatile Organic Compounds Detection: Materials, Application, and Prospects

Rare Metals, EarlyView.
ABSTRACT The detection of volatile organic compounds (VOCs) holds significant implications in environmental monitoring and disease diagnosis. Traditional gas detection technologies are constrained by complex operation and high cost, thereby failing to satisfy real‐time detection demands.
Yuening Wang, Lin Qiu, Jian Yu, Wen Ma, Xiaoyu Song, Mingjian Zhang, Yujiao Xie, Aochi Liu, Li Sun, Xiangyu Meng, Jie Lin, Xiaotian Wang   +11 more
wiley   +1 more source

Phase-1 study of vamotinib (PF-114), a 3rd generation BCR::ABL1 tyrosine kinase-inhibitor, in chronic myeloid leukaemia. [PDF]

Ann Hematol
Turkina A, Vinogradova O, Lomaia E, Shatokhina E, Shukhov O, Chelysheva E, Shikhbabaeva D, Nemchenko I, Petrova A, Bykova A, Siordiya N, Shuvaev V, Mikhailov I, Novikov F, Shulgina V, Hochhaus A, Ottmann O, Cortes J, Gale RP, Chilov G.   +19 more
europepmc   +2 more sources

Real-world evidence of imatinib treatment in younger and older patients with chronic myeloid leukaemia: A retrospective single centre analysis. [PDF]

Oncol Lett
Graf R, Kreye G, Pecherstorfer M, Singer J.   +3 more
europepmc   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

DE-ESCALATION OF TYROSINE KINASE INHIBITOR THERAPY IS SAFE IN CHRONIC MYELOID LEUKAEMIA IN DURABLE MOLECULAR RESPONSE (>= MR3 FOR >= 12 MONTHS): INITIAL RESULTS IN THE BRITISH DESTINY STUDY [PDF]

, 2016
Apperley, J, Clark, R, Coffey, T, Copland, M, Foroni, L, O'Brien, S, Pocock, C, Polydoros, F, Salim, R, Smith, G   +9 more
core  

Nanomedicine Meets Immunotherapy: Transforming Chimeric Antigen Receptor T Cell Treatment for Solid Tumors

Small Science, EarlyView.
This review highlights recent advances in nanomedicine that enhance chimeric antigen receptor (CAR) T cell therapy against solid tumors. It discusses key barriers to CAR T cell efficacy and outlines nanotechnology‐based strategies to improve tumor targeting, remodel the immunosuppressive microenvironment, and integrate nanomaterials into CAR T cell ...
Stephen O’Rourke, Nuo Xu, Hongjun Wang, Hexin Chen   +3 more
wiley   +1 more source

Single‐cell RNA sequencing revealed the T‐cell heterogeneity and exhaustion subsets of Helicobacter pylori‐induced gastritis‐to‐cancer transformation

VIEW, EarlyView.
H. pylori infection is a major cause of stomach cancer, but its effect on immune cells in tumors is unclear. Using single‐cell sequencing, we mapped the stomach tumor environment and discovered a specific exhausted T‐cell subtype, marked by the FYB1 gene, that is abundant in H. pylori‐positive tumors and linked to patient prognosis. Our findings reveal
Yanhui Yang, Yanxia Liu, Xiaole Guo, Zhaorun Li, Ziyu Liu, Shuming Zhang, Yuma Yang, Jun Liu, Shoucheng Ma, Linke Ma, Xianmei Chen, Xue Li, Yuanyuan Tang, Xiaoling Ding, Xiaofei Li, Qian Hao, Yanjie You, Tingting Yang, Qingrui Li, Xue Zhang, Sihan Zhang, Hengjun Gao, Shengjuan Hu   +22 more
wiley   +1 more source

A novel imatinib analogue inhibitor of chronic myeloid leukaemia: design, synthesis and characterization-explanation of its folded conformation. [PDF]

R Soc Open Sci
Moreno-Fuquen R, Avellaneda-Tamayo JF, Arango-Daraviña K, Ellena J, Kennedy AR.   +4 more
europepmc   +1 more source

Asciminib for chronic myeloid leukaemia. [PDF]

Aust Prescr, 2022
europepmc   +1 more source

Interventional oncology in children: Where are we now?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel, Fernando Gómez Muñoz   +1 more
wiley   +1 more source