Results 271 to 280 of about 71,029 (345)

Burden of haematological malignancies among children, adolescents and young adults: Global and high‐income region insights from the GBD 2021 study

British Journal of Haematology, EarlyView.
Summary This study provides a comprehensive assessment of haematological malignancies among children, adolescents and young adults aged 0–24 years, using data from the Global Burden of Disease 2021 across 204 countries from 1990 to 2021. We found that global incidence and prevalence remained relatively stable, with approximately 150 000 new cases and ...
Shujuan Xu, Baihua Yang, Xinxin Liu, Zhenshu Xu, Ping Weng   +4 more
wiley   +1 more source

Insights into existing and futuristic treatment approach for chronic myeloid leukaemia. [PDF]

Indian J Med Res
Tyagi S, Singh A, Sharma N, Chaturvedi R, Kushwaha HR.   +4 more
europepmc   +1 more source

Assessment of measurable residual disease in ovarian tissue collected for fertility preservation in patients in remission from acute myeloid leukaemia: A pilot study

British Journal of Haematology, EarlyView.
Summary Allogeneic haematopoietic stem cell transplantation (ASCT) is a curative treatment for acute myeloid leukaemia (AML) but carries a high risk of gonadotoxicity. Ovarian tissue cryopreservation (OTC) offers a fertility preservation option, yet its safety in AML remains uncertain due to the risk of leukaemic cell reintroduction. The FERTILAM pilot
Augustin Boudry, Florian Chevillon, Alice Marceau‐Renaut, Thorsten Braun, Thomas Boyer, Nathalie Helevaut, Elise Fournier, Sandrine Geffroy, Nicolas Boissel, Emmanuelle Clappier, Claude Preudhomme, Nicolas Duployez, Catherine Poirot, Laurène Fenwarth   +13 more
wiley   +1 more source

Challenges determining the best target duration of deep molecular response after which to attempt achieving therapy-free remission in chronic myeloid leukaemia. [PDF]

Leukemia
Gong X, Zhai X, Shen Q, Gale RP, Chen J.
europepmc   +1 more source

Hypomethylating agents in vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS): A systematic review

British Journal of Haematology, EarlyView.
Summary VEXAS syndrome (vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic) is an X‐linked, systemic, haemato‐inflammatory syndrome caused by somatic mutations in the UBA1 gene. No standardized treatment guidelines exist, but evidence is emerging that treatment with hypomethylating agents (HMAs) can induce improvement of the inflammatory symptoms,
Fieke W. Hoff, Roochi Trikha, Emma M. Groarke, Bhavisha A. Patel   +3 more
wiley   +1 more source

Phase II study of the triple combination of rabbit ATG, ciclosporin and eltrombopag in patients with transfusion‐dependent aplastic anaemia: West Japan Hematology Study Group (W‐JHS) AA02 trial

British Journal of Haematology, EarlyView.
Summary The efficacy of a triple combination of rabbit anti‐human thymocyte immunoglobulin (rATG), ciclosporin and eltrombopag (EPAG) was prospectively evaluated in patients with severe or transfusion‐dependent non‐severe aplastic anaemia (SAA) across 29 institutions in Japan. Sixty patients were enrolled, of whom 48 had SAA. The primary end‐point, the
Fumi Nakamura, Ken Ishiyama, Ritsuro Suzuki, Hiroyuki Maruyama, Yasushi Onishi, Kensuke Usuki, Hideo Koh, Katsuto Takenaka, Ryunosuke Saiki, Seishi Ogawa, Kana Matsumoto, Takuto Takahashi, Kazuyoshi Hosomichi, Yoshitaka Zaimoku, Kenichi Yoshimura, Itaru Matsumura, Koichi Akashi, Shinji Nakao   +17 more
wiley   +1 more source

Phenotypically plastic drug-resistant chronic myeloid leukaemia cell line displays enhanced cellular dynamics in a zebrafish xenograft model. [PDF]

J Cell Mol Med
Baykal S, Yuce Z, Ozhan G.
europepmc   +1 more source

The impact of scaRNA12 deregulation on p53‐mediated cellular stress response in B‐cell precursor acute lymphoblastic leukaemia

British Journal of Haematology, EarlyView.
Summary Small nucleolar ribonucleic acids (snoRNAs) are a class of small non‐coding RNAs involved in the post‐transcriptional modification of ribosomal RNAs (rRNA) and small nuclear RNAs (snRNA). Mounting evidence indicates that specific snoRNAs are drivers of oncogenesis, but their role in B‐cell precursor acute lymphoblastic leukaemia (BCP‐ALL) is ...
Martijn W. C. Verbeek, Mathijs A. Sanders, Dwin G. B. Grashof, Remco M. Hoogenboezem, Iris van Zuijen, Annemarieke Bos, Trui van Gulck, Rosan Olsman, Rishov Mukhopadhyay, Eric M. J. Bindels, Peter J. M. Valk, Harmen J. G. van de Werken, Vincent H. J. van der Velden, Stefan J. Erkeland   +13 more
wiley   +1 more source

Late presentation of chronic myeloid leukaemia patients in a low-income country: the prognostic implications and impact on treatment outcome. [PDF]

BMC Res Notes
Nelson EA, Ahmed IO, Bolarinwa RA, Adeagbo BA, Adegbola AJ, Salawu L, Bolaji OO, Durosinmi MA.   +7 more
europepmc   +1 more source