Results 341 to 350 of about 125,713 (396)

(−)‐Epigallocatechin‐3‐gallate induces cell apoptosis in chronic myeloid leukaemia by regulating Bcr/Abl‐mediated p38‐MAPK/JNK and JAK2/STAT3/AKT signalling pathways

Clinical and Experimental Pharmacology and Physiology, 2018
Epigallocatechin‐3‐gallate (EGCG), a major polyphenolic constituent of green tea, possesses remarkable chemopreventive and therapeutic potential against various types of cancer, including leukaemia.
Xiang Xiao, Kai-qi Jiang, Yun-xiao Xu, Hongling Peng, Zhihua Wang, Sufang Liu, Guangsen Zhang   +6 more
semanticscholar   +1 more source

Molecular pathogenesis of chronic myeloid leukaemia

Expert Reviews in Molecular Medicine, 2003
The abnormal haemopoietic precursor cells of chronic myeloid leukaemia (CML) carry the cytogenetic abnormality [t(9;22)(q34;q11)] – a reciprocal translocation that results in the expression of a chimaeric protein derived from the fused BCR and ABL genes.
Smith, D, Burthem, J, Whetton, Anthony
openaire   +4 more sources

PROMYELOCYTIC CRISIS OF CHRONIC MYELOID LEUKAEMIA

British Journal of Haematology, 1987
no ...
Emilia G, SACCHI, Stefano, Selleri L, Zucchini P, Artusi T, Torelli U.   +5 more
openaire   +4 more sources

Chronic Lymphocytic Leukaemia Developing in the Course of Chronic Myeloid Leukaemia

Leukemia & Lymphoma, 2002
Both chronic myeloid leukaemia (CML) and chronic lymphocytic leukaemia (CLL) are rare illnesses. Their co-existence has been previously reported, typically with CML following CLL. We report to our knowledge the first case of CLL developing some years after initial diagnosis of Philadelphia (Ph) chromosome positive CML.
Rahuman Salim, Ke Lin, Lihui Wang, Richard E. Clark   +3 more
openaire   +3 more sources

Chronic Myeloid Leukaemia

2018
Chronic myeloid leukaemia (CML) was recognized in the 1970s by Janet Rowley to be a genetically simple malignancy; resulting as a consequence of a balanced translocation between chromosome 9 and 22. This provided vital insights into the molecular aberration, in the 1990s, which ushered in the current ‘precision medicine’ era, not only for patients of ...
openaire   +1 more source

i. Some Observations on Chronic Myeloid Leukaemia

The British Journal of Radiology, 1953
Observations on patients made during a therapeutic trial of Myleran (1 : 4-dimethanesulphonyloxybutane) in chronic myeloid leukaemia lent support to the following views, which are presented for discussion. 1. Anaemia in this disease results from marrow replacement by leukaemic tissue. 2.
openaire   +3 more sources

Chronic Myeloid Leukaemia and a Myasthenic Syndrome

Acta Haematologica, 1979
This is the first report of a case of chronic myeloid leukaemia (CML) complicated by myasthenic syndrome. The patient suffered two prolonged periods of idiosyncratic busulphan-induced marrow aplasia, the first occurring 5 months after busulphan was stopped.
Miriam A. Wohl, Keith Wood
openaire   +3 more sources

Chronic myeloid leukaemia in a haemophiliac

Blut, 1987
The present report describes for the first time in the English literature adult type Philadelphia (Ph 1) chromosome positive chronic myeloid leukaemia (CML) in a 40 year old male haemophiliac who had been treated with transfusions of fresh blood and fresh frozen plasma since his childhood.
A. S. Deshpande, Kanjaksha Ghosh, K.C. Das, D. Mohanty   +3 more
openaire   +2 more sources

Why chronic myeloid leukaemia cannot be cured by tyrosine kinase-inhibitors

Leukemia, 2021
M. Baccarani, R. Gale
semanticscholar   +1 more source

Impact of tailored patient education on adherence of patients with chronic myeloid leukaemia to tyrosine kinase inhibitors: a randomized multicentre intervention study.

Journal of Advanced Nursing, 2016
AIMS The aim of this study was to evaluate the influence of tailored patient education on adherence to tyrosine kinase inhibitor medication among patients with chronic myeloid leukaemia.
M. Kekäle, T. Söderlund, Perttu Koskenvesa, K. Talvensaari, M. Airaksinen   +4 more
semanticscholar   +1 more source