Results 31 to 40 of about 71,029 (345)

A novel three-colour fluorescence in situ hybridization approach for the detection of t(7;12)(q36;p13) in acute myeloid leukaemia reveals new cryptic three way translocation t(7;12;16) [PDF]

, 2013
© 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).The t(7;12)(q36;p13 ...
Abdulbasit Naiel, Andreasson, Beverloo, Cho, Elena Fleischman, Grigory Tsaur, Hollington, Jochen Harbott, Michael Vetter, Olga Plekhanova, Olga Sokova, Raimondi, Sabrina Tosi, Wildenhain, Wlodarska   +14 more
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Dipeptidylpeptidase IV (CD26) defines leukemic stem cells (LSC) in chronic myeloid leukemia [PDF]

, 2014
Chronic myeloid leukemia (CML) is a stem cell (SC) neoplasm characterized by the BCR/ABL1 oncogene. Although mechanisms of BCR/ABL1-induced transformation are well-defined, little is known about effector-molecules contributing to malignant expansion and ...
Bilban, Martin, Blatt, Katharina, Cerny-Reiterer, Sabine, Herndlhofer, Susanne, Herrmann, Harald, Hoermann, Grego, Holyoake, Tessa L., Mannhalter, Christine, Mayerhofer, Matthias, Rulicke, Thomas, Sadovnik, Irina, Sperr, Wolfgang R., Stefanzl, Gabriele, Streubel, Berthold, Valent, Peter, Willmann, Michael   +15 more
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Body mass index does not impact on molecular response rate of chronic myeloid leukaemia patients treated frontline with second generation tyrosine kinase inhibitors. [PDF]

, 2017
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Alimena G, Breccia M., Canichella M, Colafigli G, Diverio D, Foà R, Latagliata R, Molica M   +7 more
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Chronic myeloid leukaemia with lymphosarcoma [PDF]

Journal of Clinical Pathology, 1963
The clinical and pathological features of two patients with chronic myeloid leukaemia who died from lymphosarcoma are described. Both had been treated with busulphan which, at the time of development of lymphosarcoma and at death, appeared to be controlling the leukaemia satisfactorily.
J S, HOWELL, A G, WHITFIELD
openaire   +2 more sources

A Trib2-p38 axis controls myeloid leukaemia cell cycle and stress response signalling [PDF]

, 2018
Trib2 pseudokinase is involved in the etiology of a number of cancers including leukaemia, melanoma, ovarian, lung and liver cancer. Both high and low Trib2 expression levels correlate with different types of cancer.
Carmody, Ruaidhri J., Chaudhury, Shahzya, Keeshan, Karen, Magee, Aoife, Salomé, Mara, Sarrou, Evgenia, Yalla, Krishna   +6 more
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A Case Report on the Progression of Myeloid Sarcoma to Form Multiple Metastatic Deposits without Developing Acute Myeloid Leukaemia

Case Reports in Hematology, 2015
Introduction. Myeloid sarcomas (MS) are rare tumours occurring at extramedullary sites. They are usually associated with other haematology disorders such as acute myeloid leukaemia, myelodysplastic syndrome, and chronic myeloproliferative neoplasms. They
Sunita Kohli, Mark Lee, Scott Marshall
doaj   +1 more source

Role of Angiogenesis and Endothelialmesenchymal Transition in Bone Marrow Fibrosis Associated with Haematopoietic Neoplasms: A Cross-sectional Immunohistochemical Analysis [PDF]

Journal of Clinical and Diagnostic Research
Introduction: The bone marrow examination is an essential investigation in the diagnosis and management of many haematological disorders. The integration of all investigations, including peripheral blood analysis, bone marrow aspirate, and trephine ...
Shweta Agarwal, Shruti Sharma, Monal Trisal, Zeeba S Jairajpuri, Sujala Kapur, Sumita Saluja, Purnima Paliwal   +6 more
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Unprecedented behaviour of chronic myeloid leukaemia [PDF]

Journal of Clinical and Scientific Research, 2016
We report the occurrence of leukaemic infiltration of cervical spinal cord secondary to chronic myeloid leukaemia (CML) in a 31-year-old male patient. He presented with left upper limb monoplegia.
Balambika RG, Vanakamamidi VS, Sudheer Reddy K, Ananth Pai, Reddy D, Meenaksisundaram M, Vijayalakshmidevi B, Patnayak R, Thota A   +8 more
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Identification of Bruton's tyrosine kinase as a therapeutic target in acute myeloid leukemia [PDF]

, 2014
Bruton's tyrosine kinase (BTK) is a cytoplasmic protein found in all hematopoietic cell lineages except for T cells. BTK mediates signalling downstream of a number of receptors.
Advani, Alam, Ashino, Baba, Bendall, Billottet, Burger, Burger, Byrd, Chang, Cordle, Dasmahapatra, David J. MacEwan, de Weers, Dos Santos, Doyle, Fiedler, Gallay, Grandage, Gu, Guzman, Hahn, Herman, Herrmann, Honda, Honigberg, Horwood, Ishii, Juliusson, Kawakami, Kim, Kojima, Kristian M. Bowles, Kvinlaug, Lyubov Zaitseva, Megan Y. Murray, Min, Mohamed, Nanri, Park, Quek, Renneville, Rushworth, Rushworth, Rushworth, Shinners, Sivina, Spiekermann, Stuart A. Rushworth, Sujobert, Tai, Tamburini, Tomasson, Tsukada, Vellenga, Venkataraman, Vetrie, Welch, Westermann, Zaitseva   +59 more
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Targeting PI3Kδ and PI3Kγ signalling disrupts human AML survival and bone marrow stromal cell mediated protection [PDF]

, 2016
Phosphoinositide-3-kinase (PI3K) is an enzyme group, known to regulate key survival pathways in acute myeloid leukaemia (AML). It generates phosphatidylinositol-3,4,5-triphosphate, which provides a membrane docking site for protein kinaseB activation ...
Alves, Arcaro, Asou, Bouscary, Bouscary, Bouscary, Bowles, Carroll, Carroll, DiPersio, Druker, Esmaeili-Mahani, Finan, Gandhi, Giese, Gilliland, Hirsch, Johnson, Jordan, Kahl, Khwaja, Khwaja, Ko, Konopleva, MacEwan, MacEwan, Niitsu, Pettitt, Pocock, Preudhomme, Recher, Ronnstrand, Rushworth, Solary, Ulrich, Wei, Wymann, Wymann   +37 more
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