Results 51 to 60 of about 125,713 (396)

A novel three-colour fluorescence in situ hybridization approach for the detection of t(7;12)(q36;p13) in acute myeloid leukaemia reveals new cryptic three way translocation t(7;12;16) [PDF]

, 2013
© 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).The t(7;12)(q36;p13 ...
Abdulbasit Naiel, Andreasson, Beverloo, Cho, Elena Fleischman, Grigory Tsaur, Hollington, Jochen Harbott, Michael Vetter, Olga Plekhanova, Olga Sokova, Raimondi, Sabrina Tosi, Wildenhain, Wlodarska   +14 more
core   +2 more sources

Slovenian recommendations for the management of chronic myeloid leukaemia

Zdravniški Vestnik, 2018
The paper presents recommendations for the management of patients with chronic myeloid leukaemia. Clinical manifestations, diagnostics, treatment and monitoring of treatment are presented.
Irena Preložnik Zupan, Karla Rener, Helena Podgornik, Matjaž Sever, Martina Fink, Mateja Grat, Tadej Pajič   +6 more
doaj   +1 more source

Apoptotic effect of Bulbine Natalensis and Chlorophytum Comosum in myelogenous Leukemia K562 cell line

Brazilian Journal of Biology, 2021
Bulbine natalensis and Chorophytum comosum are potential medicinal source for the treatment of cancers. Chronic myeloid leukaemia is a hematopoietic stem cells disorder treated by tyrosine kinase inhibitors but often cause recurrence of the leukaemia ...
B. Padayachee, F. Odun-Ayo, L. Reddy
doaj   +1 more source

European LeukemiaNet recommendations for the management and avoidance of adverse events of treatment in chronic myeloid leukaemia

Leukemia, 2016
Most reports on chronic myeloid leukaemia (CML) treatment with tyrosine kinase inhibitors (TKIs) focus on efficacy, particularly on molecular response and outcome.
J. Steegmann, M. Baccarani, Massimo Breccia, L. F. Casado, Valentín García-Gutiérrez, A. Hochhaus, Dong-Kee Kim, Theo-D. Kim, H. Khoury, P. L. Coutre, J. Mayer, D. Milojkovic, K. Porkka, D. Réa, Giovanni Rosti, Susanne Saussele, Ruediger Hehlmann, Richard E. Clark   +17 more
semanticscholar   +1 more source

A Dasatinib-Induced Chylothorax Persisting After the Discontinuation of Dasatinib

European Journal of Case Reports in Internal Medicine, 2022
Dasatanib is a second-generation tyrosine kinase inhibitor with activity on the BCR-ABL fusion gene. it is used in the treatment of BCR-ABL positive chronic myeloid leukaemia and has the known side effect of pleural effusion.
Nicolas Bradt, Frederic Olbrechts, Patrick Alexander, Alexander Salembier   +3 more
doaj   +1 more source

Cardiovascular toxicity induced by TKIs in patients with chronic myeloid leukaemia: Are women and men different? [PDF]

ESC Heart Fail
This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Madaudo C, Di Lisi D, Cannatà A, Manfrè F, Vullo C, Santoro M, Botta C, Mancuso S, Siragusa S, Galassi AR, Novo G.   +10 more
europepmc   +2 more sources

Body mass index does not impact on molecular response rate of chronic myeloid leukaemia patients treated frontline with second generation tyrosine kinase inhibitors. [PDF]

, 2017
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Alimena G, Breccia M., Canichella M, Colafigli G, Diverio D, Foà R, Latagliata R, Molica M   +7 more
core   +1 more source

The antiproliferative activity of kinase inhibitors in chronic myeloid leukemia cells is mediated by FOXO transcription factors [PDF]

, 2014
Chronic myeloid leukemia (CML) is initiated and maintained by the tyrosine kinase BCR-ABL which activates a number of signal transduction pathways, including PI3K/AKT signaling and consequently inactivates FOXO transcription factors.
Bhatia, Birkenkamp, Breitling, Bruennert, Brunet, Burgering, Chomel, Chu, Copland, Corbin, Druker, Duy, Essafi, Fernandez de Mattos, Ghaffari, Goldman, Graham, Hamilton, Hurtz, Ito, Jorgensen, Kikuchi, Komatsu, Koschmieder, Mahon, Matsumoto, Miyamoto, Naka, Pellicano, Pellicano, Pellicano, Ross, Ross, Rowley, Sarbassov, Skorski, Tothova, Tothova, Trotman   +38 more
core   +2 more sources

Adoptive Immunotherapy in Chimeras with Donor Lymphocytes [PDF]

, 2003
Allogeneic stem cell transplantation has a well-defined indication in the treatment of hematological malignancies. The beneficial immune effect of allogeneic marrow transplantation has long been known, but only recently have methods been developed to ...
Chen, Xiao, Guenther, Wolfgang, Kolb, Hans-Jochem, Ledderose, Georg, Roskrow, Marie, Schleuning, Michael, Schmid, Christoph, Weber, Martin, Woiciechowski, Anja   +8 more
core   +1 more source

Inhibition of MDR1 does not sensitize primitive chronic myeloid leukemia CD34⁺ cells to imatinib [PDF]

, 2009
<p><b>Objective:</b> To investigate the interaction of imatinib mesylate (IM) with the clinically relevant adenosine triphosphate-binding cassette efflux transporter MDR1 (ABCB1) in cells from patients with chronic myeloid leukemia (CML)
Hatziieremia, S., Holyoake, T.L., Jordanides, N.E., Jorgensen, H.G., Mountford, J.C.   +4 more
core   +1 more source