Results 301 to 310 of about 200,211 (350)
Genetic Variants in Oxidative Stress-Related Genes and Their Impact on Prognosis and Treatment Response in Chronic Myeloid Leukemia Patients. [PDF]
Alves R+11 more
europepmc +1 more source
PTBP2 promotes cell survival and autophagy in chronic myeloid leukemia by stabilizing BNIP3. [PDF]
Barik B+7 more
europepmc +1 more source
Impact of CHEK2 germline variants on haematological malignancy risk and outcomes of allogeneic HSCT
British Journal of Haematology, EarlyView.
Atte K. Lahtinen+15 more
wiley +1 more source
Chronic Myeloid Leukemia [PDF]
Over the past twenty years, clinical and laboratory studies have led to important new insights into the biology of chronic myeloid leukemia. Basic science has defined the molecular pathogenesis of chronic myeloid leukemia (CML) as unregulated signal transduction by the Bcr-Abl tyrosine kinase.
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Current Opinion in Hematology, 1997
Progress has been made in understanding BCR-ABL-positive leukemias. A new transcript (p230BCR-ABL) has been characterized that is associated with Ph-positive chronic neutrophilic leukemia. The ATM protein appears to be a regulator of ABL activity in response to irradiation damage.
John M. Goldman, Michael W. Deininger
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Progress has been made in understanding BCR-ABL-positive leukemias. A new transcript (p230BCR-ABL) has been characterized that is associated with Ph-positive chronic neutrophilic leukemia. The ATM protein appears to be a regulator of ABL activity in response to irradiation damage.
John M. Goldman, Michael W. Deininger
openaire +4 more sources
Asciminib in chronic myeloid leukemia
Drugs of Today, 2022Despite the fact that, in the last years, life expectancy of chronic myeloid leukemia (CML) patients has reached that of the normal population, a significant proportion of CML patients is likely to fail treatment with first- or second-generation tyrosine kinase inhibitors (TKIs).
Assanto, Giovanni Manfredi+2 more
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