Results 321 to 330 of about 200,211 (350)
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Splenectomy in Chronic Myeloid Leukemia
Annals of Internal Medicine, 1978We review splenectomy in chronic myeloid leukemia, emphasizing recent studies that have evaluated early splenectomy during the chronic phase of the disease. Despite current interest in splenectomy in chronic myeloid leukemia, uncontrolled clinical trials to date suggest that the operation during the early phase neither delays the onset of blastic ...
David J. Wolf+2 more
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2012
It is estimated that 4,870 new cases of chronic myeloid leukemia (CML) will be diagnosed in 2010, representing approximately 11 % of all leukemias (Jemal et al. 2010). The median age of diagnosis reported in 2003–2007 was 65 years of age (Altekruse et al. 2010). The etiology of CML remains unclear; evidence is lacking demonstrating hereditary influence.
Kapil N. Bhalla+2 more
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It is estimated that 4,870 new cases of chronic myeloid leukemia (CML) will be diagnosed in 2010, representing approximately 11 % of all leukemias (Jemal et al. 2010). The median age of diagnosis reported in 2003–2007 was 65 years of age (Altekruse et al. 2010). The etiology of CML remains unclear; evidence is lacking demonstrating hereditary influence.
Kapil N. Bhalla+2 more
openaire +2 more sources
2007
In attempting to apply evidence-based medicine in the treatment of chronic myeloid leukemia (CML), it must be acknowledged that a randomized study comparing imatinib mesylate therapy and allogeneic stem cell transplantation (SCT) has not been conducted.
openaire +2 more sources
In attempting to apply evidence-based medicine in the treatment of chronic myeloid leukemia (CML), it must be acknowledged that a randomized study comparing imatinib mesylate therapy and allogeneic stem cell transplantation (SCT) has not been conducted.
openaire +2 more sources
Treatment of Chronic Myeloid Leukemia
Annual Review of Medicine, 1980Most known chemotherapy agents, used singly, may induce remission of CML. Those that best alleviate symptoms (anemia, splenomegaly, etc) do not change either the Ph' chromosome anomaly in the hemopoietic cells nor the median delay of 3--4 years before fatal blastic transformation.
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Ponatinib for Chronic Myeloid Leukemia
New England Journal of Medicine, 2012The treatment of patients with chronic myeloid leukemia (CML) must be ranked as one of the great medical success stories of the past 30 years. The demonstration that the Philadelphia (Ph) chromosome carries a fusion gene formed by the juxtaposition of BCR and ABL genetic sequences focused attention on the possibility that the tyrosine kinase activity ...
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Restoring metabolism of myeloid cells reverses cognitive decline in ageing
Nature, 2021Congcong Wang+2 more
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A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells
Cell, 2021Ziyi Li, Sijin Cheng, Ranran Gao
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