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Chronic obstructive pulmonary disease
Nature Reviews Disease Primers, 2015Chronic obstructive pulmonary disease (COPD) is a common disease with high global morbidity and mortality. COPD is characterized by poorly reversible airway obstruction, which is confirmed by spirometry, and includes obstruction of the small airways (chronic obstructive bronchiolitis) and emphysema, which lead to air trapping and shortness of breath in
Peter J, Barnes +6 more
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Chronic Obstructive Pulmonary Disease
Comprehensive Physiology, 2014AbstractCOPD is characterized by airflow limitation that is not fully reversible. The morphological basis for airflow obstruction results from a varying combination of obstructive changes in peripheral conducting airways and destructive changes in respiratory bronchioles, alveolar ducts, and alveoli. A reduction of vascularity within the alveolar septa
BRUSASCO, VITO, Martinez, Fernando
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Chronic obstructive pulmonary disease
The Lancet, 2017Chronic obstructive pulmonary disease (COPD) kills more than 3 million people worldwide every year. Despite progress in the treatment of symptoms and prevention of acute exacerbations, few advances have been made to ameliorate disease progression or affect mortality.
Klaus F, Rabe, Henrik, Watz
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Chronic obstructive pulmonary disease
Nursing Standard, 2002Chronic obstructive airways disease is a chronic, progressive disorder characterised by airways obstruction. The author discusses the management of patients with this condition, and examines the use of bronchodilator therapy, inhaled steroids, smoking cessation and pulmonary rehabilitation.
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Chronic Obstructive Pulmonary Disease
Journal of the American Academy of Nurse Practitioners, 2001Each month the Journal of the American Academy of Nurse Practitioners' clinical practice guideline (CPG) column reviews a different set of clinical recommendations. It is important that those in practice be aware of guidelines applicable to the needs of their patients and judge the available guidelines.
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Chronic Obstructive Pulmonary Disease
Clinics in Geriatric Medicine, 1986Morbidity and mortality associated with chronic airway disease are expected to continue to rise over the coming years. Accordingly, increased attention will need to be directed toward the diagnosis and treatment of COPD in the elderly population. Cessation of cigarette smoking should be pursued in all patients regardless of age.
D A, Mahler, P B, Barlow, R A, Matthay
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Update on the Pathogenesis of Chronic Obstructive Pulmonary Disease.
New England Journal of Medicine, 2019Update on the Pathogenesis of COPD A pair of review articles examines our current understanding of the biology, diagnosis, and treatment of chronic obstructive pulmonary disease.
A. Agustí, J. Hogg
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Update on Clinical Aspects of Chronic Obstructive Pulmonary Disease.
New England Journal of Medicine, 2019Update on Clinical Aspects of COPD A pair of review articles examines our current understanding of the biology, diagnosis, and treatment of chronic obstructive pulmonary disease.
B. Celli, J. Wedzicha
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Severe Chronic Obstructive Pulmonary Disease
Clinical Reviews in Allergy & Immunology, 2003Chronic obstructive pulmonary disease (COPD) exacts a heavy toll on society, yet its prevention, diagnosis and treatment receives inadequate attention from both the medical community and from society at large. Guidelines released in 2001 from the Global Initiative for Chronic Obstructive Lung Disease (GOLD) are aimed at redressing this inequity.
Ken Y, Yoneda +2 more
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Chronic Obstructive Pulmonary Disease Pathogenesis
Clinics in Chest Medicine, 2020Chronic obstructive pulmonary disease (COPD) has been traditionally considered a self-inflicted disease caused by tobacco smoking. Current available evidence, however, indicates that the pathogenesis of COPD needs to consider the dynamic and cumulative nature of a series of environment (including smoking plus other exposures)-host interactions that ...
Alvar, Agusti, Rosa, Faner
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