Results 101 to 110 of about 31,501 (220)
Systemic Corticosteroids in the Management of Sinonasal Disease: An Evidence‐Based Expert Review
ABSTRACT Background Chronic rhinosinusitis (CRS) is a prevalent, heterogeneous inflammatory disease associated with significant morbidity. Systemic corticosteroids (SCS) are commonly prescribed for their anti‐inflammatory effects, but cumulative exposure carries risks, including metabolic, cardiovascular, and skeletal complications.
Andrew Thamboo +28 more
wiley +1 more source
Objective Eosinophilic granulomatosis with polyangiitis (EGPA) is a small vessel vasculitis characterized by eosinophilia, asthma, and ear, nose, and throat (ENT) involvement. Although glucocorticoids (GCs) are effective in controlling symptoms, relapses and GC dependence are common. The aim of this study was to develop predictive models for vasculitis
Matthias Papo +35 more
wiley +1 more source
ABSTRACT Background Non‐typeable Streptococcus pneumoniae (NT‐Sp) strains lack detectable capsules and are often missed by traditional serotyping. While associated primarily with asymptomatic carriage, NT‐Sp has emerged as a key player in antimicrobial resistance (AMR) gene dissemination and serotype replacement in the post‐vaccine era. This systematic
Robert K. Reeks +2 more
wiley +1 more source
Environmental toxicants may disrupt developmental pathways via strong molecular docking interactions with hub FGF proteins (FGF9 and FGF4) like dibenzo‐p‐dioxin (−7.2 kcal/mol) at the ASN146 residue of FGF9, driving congenital malformations as revealed by PPI networks and toxicity profiling.
Adarsh Kumar Shukla +3 more
wiley +1 more source
Nine Years of Experience With Bonebridge: Long‐Term Clinical and Audiological Outcomes
ABSTRACT Introduction The active bone conduction hearing implant Bonebridge is a therapeutic option for hearing rehabilitation of patients with conductive and mixed hearing loss, as well as for those with unilateral sensorineural hearing loss. It has demonstrated satisfactory audiological gain, comparable to conventional hearing aids and percutaneous ...
Tallita dos Santos Souza Boaventura +3 more
wiley +1 more source
ABSTRACT Introduction Chronic rhinosinusitis (CRS) and Eustachian tube dysfunction (ETD) frequently coexist, yet objective data quantifying their relationship remain scarce. Because both conditions can reflect shared mucosal inflammation, we investigated whether adults with objectively verified ETD harbor a larger paranasal sinus inflammatory burden on
Dachan Kim +2 more
wiley +1 more source
Corynebacterium amycolatum: An Emerging Pathogen in Chronic Otitis Media. [PDF]
Ibarra-Armenta G +5 more
europepmc +1 more source
ABSTRACT Background Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder, and despite advances in next‐generation sequencing, a substantial proportion of clinically suspected pediatric cases remain without a molecular diagnosis.
Tilbe Hakçıl Öz +4 more
wiley +1 more source
A Call for Screening: Hearing Loss and Chronic Otitis Media in Immigrants to Sweden. [PDF]
Kraft S +3 more
europepmc +1 more source
We report a case of severe asthma with chronic rhinosinusitis with nasal polyps and eosinophilic otitis media that was successfully controlled by switching biologic therapy from dupilumab to mepolizumab. Careful monitoring of disease activity and consideration of biologic switching may help achieve optimal control with currently available biologics ...
Tomoko Tajiri +5 more
wiley +1 more source

