Results 21 to 30 of about 1,745,006 (315)
Substance P aggravates ligature-induced periodontitis in mice
Frontiers in Immunology, 2023 Periodontitis is one of the most common oral diseases in humans, affecting over 40% of adult Americans. Pain-sensing nerves, or nociceptors, sense local environmental changes and often contain neuropeptides. Recent studies have suggested that nociceptors
Yasir Dilshad Siddiqui +8 more
doaj +1 more source
NeuroImage: Clinical, 2018 Until recently, the predominant pathology of chronic pelvic pain conditions was thought to reside in the peripheral tissues. However, mounting evidence from neuroimaging studies suggests an important role of the central nervous system in the pathogenesis
Daniel E. Harper +7 more
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Quality of life and chronic pain four years after gastrointestinal surgery [PDF]
, 2006 PURPOSE: Little is known about the prevalence of chronic postsurgical pain after gastrointestinal surgery. This study was designed to assess the prevalence of chronic pain and quality of life in a cohort of patients who underwent surgery for benign and ...
Bruce, Julie, Krukowski, Zygmunt H.
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Pain Research and Management, 2011 In the United States, duloxetine has been approved for the treatment of major depressive disorder, diabetic peripheral neuropathic pain and fibromyalgia in the adult population.
Ludmyla Kachko +4 more
doaj +1 more source
Injustice perceptions about pain: parent–child discordance is associated with worse functional outcomes [PDF]
, 2018 Pain is experienced within and influenced by social environments. For children with chronic pain, the child–parent relationship and parental beliefs about pain are particularly important and may influence pain outcomes. Pain-related injustice perceptions
Hirsh, Adam T. +5 more
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Transcriptome analysis of trigeminal ganglia following masseter muscle inflammation in rats
Molecular Pain, 2016 Background Chronic pain in masticatory muscles is a major medical problem. Although mechanisms underlying persistent pain in masticatory muscles are not fully understood, sensitization of nociceptive primary afferents following muscle inflammation or ...
Man-Kyo Chung DMD, PhD +3 more
doaj +1 more source
Early Relationships of a Low‐Energy Diet With Symptoms of Fibromyalgia
ACR Open Rheumatology, 2022 Objective Previous studies have demonstrated that weight loss has been shown to improve pain in weight‐bearing joints, and more recent studies suggest that weight loss may be accompanied by improvements in pain in non–weight‐bearing regions.
Aaron Stubbs +9 more
doaj +1 more source
A randomized placebo-controlled pilot study of the efficacy and safety of D-cycloserine in people with chronic back pain. [PDF]
, 2016 BACKGROUND: Few effective pharmacological treatment options exist for chronic back pain, the leading cause of disability in the US, and all are associated with significant adverse effects. OBJECTIVE: To determine the efficacy and safety of D-cycloserine,
Apkarian, A. Vania +5 more
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Chronic regional pain and chronic pain syndromes [PDF]
Spinal Cord, 2005 This paper seeks to consider the validity and utility of two related terms in spinal and other injuries: complex regional pain syndrome (CRPS) and chronic pain syndrome (CPS). It is argued that the words chronic regional pain syndrome convey neither understanding of the condition nor of its mechanism. They simply redefine the clinical problem, but fail
openaire +2 more sources
A nationwide study of chronic pain prevalence in the general Spanish population, identifying clinical subgroups through cluster analysis. [PDF]
, 2015 Objective. This study aims to assess the prevalence of chronic pain, its characteristics, and its impact on the general Spanish population. Also, to establish chronic pain patient subgroups according to the characteristics of pain and to identify ...
Dueñas Rodríguez, María Ángeles +6 more
core +2 more sources