Results 41 to 50 of about 1,762,634 (311)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Narrative Medicine: Improving Patient Care and Shifting Office Culture [PDF]
, 2017 Chronic pain and depression are both prevalent in the Unites States and often co-exist in the same population. According to the literature, there is no consensus between providers as to the best practice of treating chronic pain and concomitant ...
Qumsiyeh, Yazen, Shatten, Julia
core +2 more sources
British pain clinic practitioners' recognition and use of the bio-psychosocial pain management model for patients when physical interventions are ineffective or inappropriate : results of a qualitative study [PDF]
, 2010 Background To explore how chronic musculoskeletal pain is managed in multidisciplinary pain clinics for patients for whom physical interventions are inappropriate or ineffective.
Anisur, Anisur +4 more
core +3 more sources
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Time of Day Influences Psychophysical Measures in Women With Burning Mouth Syndrome
Frontiers in Neuroscience, 2021 Burning mouth syndrome (BMS) is a chronic orofacial pain condition that mainly affects postmenopausal women. BMS type I patients report little to no spontaneous pain in the morning and increases in pain through the day, peaking in the afternoon ...
Janell S. Payano Sosa +12 more
doaj +1 more source
Prevalence of chronic pain in Libya before and after the uprising of 17 February 2011. [PDF]
, 2013 Two questionnaires were translated into Arabic and culturally adapted to measure chronic pain and neuropathic pain in the general population in Derna, Libya (1, 2), and then in a country-wide survey.
Tashani, OA
core +2 more sources
FEBS Open Bio, EarlyView.Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
Senses and Sciences, 2017 The patient is a 42 years old woman with entrapment syndrome of the “nerves of passage” – ilioinguinal (IING) and Iliohypogastric (IHPO) – after abdominal surgery.
Stefano Brauneis +3 more
doaj +1 more source
Towards a science and practice of resilience in the face of pain [PDF]
, 2017 The primary objective of this paper is to discuss how a resilience approach to (chronic) pain may advance our current understanding of (mal)adaptation to pain.
Alschuler +140 more
core +3 more sources
FEBS Open Bio, EarlyView.Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source